Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medicament for treating ulcerative colitis

A technology for ulcerative colitis and medicine, applied in traditional Chinese medicine or a mixture of traditional Chinese and Western medicines for the treatment of ulcerative colitis, and the field of medicines for the treatment of colitis, can solve the problems of large side effects, many side effects and great influence of intravenous medicine, and avoid the First-pass effect, increasing blood concentration, better curative effect

Inactive Publication Date: 2010-05-19
周景梅
View PDF0 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine mainly includes several types of drugs such as sulfonamides, antibiotics, hormones, and immunosuppressants in the treatment of ulcerative colitis proctitis. High toxicity and many side effects, such as oral administration of sulfonamides often cause symptoms such as nausea and vomiting, headache, general discomfort, or cause leukopenia, joint pain, rash, proteinuria, etc. Oral administration of antibiotics can easily cause gastrointestinal irritation symptoms, intravenous administration Large side effects; immunosuppressants have a greater impact on the hematopoietic function of the bone marrow, and the bone marrow should be regularly rechecked during the course of medication

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1: a selection: 3.5 grams of artificial bezoar, 1.8 grams of borneol, 21 grams of pearls, 21 grams of ivory shavings, 91 grams of Qingdai, 14 grams of Biqian (charcoal); grind into powder, sieve, mix, and form mixed powder A; b Take 1% of the mixed powder A, add 40,000 units of gentamicin and 30 ml of metronidazole solution to dissolve it into a liquid medicine. Artificial bezoar, borneol, pearls, ivory chips, Qingdai, Biqian (charcoal) are pulverized into fine powder, passed through a 100-mesh sieve, mixed evenly, and sterilized (ultraviolet disinfection, the same as in each embodiment), to obtain mixed powder A; The mixed powder A, gentamicin, and metronidazole solution are placed separately; when in use, the mixed powder A is temporarily added to the gentamicin and metronidazole solution to make a liquid medicine for retention enema.

Embodiment 2

[0037]Embodiment 2: a selection: 4.5 grams of artificial bezoar, 2.2 grams of borneol, 25 grams of pearls, 25 grams of ivory shavings, 97 grams of Qingdai, and 18 grams of Biqian; grind the powder, sieve, and mix to form mixed powder A; b take and mix 1% of powder A, add 80,000 units of gentamicin and 50 ml of metronidazole solution to dissolve into a liquid medicine. Grind artificial bezoar, borneol, pearl, ivory chips, Qingdai, Biqian (charcoal) into fine powder, pass through a 100-mesh sieve, sterilize, and mix well to obtain mixed powder A; mix mixed powder A, gentamicin, The metronidazole solution is placed separately; when in use, the mixed powder A is temporarily added to gentamicin and metronidazole solution to make a liquid medicine for retention enema.

Embodiment 3

[0038] Embodiment 3: a selection: 3 grams of Calculus Calculus, 1.5 grams of Borneolum, 19 grams of pearls, 19 grams of ivory shavings, 88 grams of Qingdai, 13 grams of Biqian (charcoal); grind the powder, sieve, mix, and form a mixed powder A; b Take 10 grams of Coptis chinensis, 10 grams of Astragalus membranaceus, and 10 grams of Cortex Phellodendri, crush them, add 120ml of water and fry for 30 to 40 minutes, take 40ml of medicinal juice, take 1% of mixed powder A, dissolve in the medicinal juice to form a medicinal liquid, and use Keep the enema.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a medicament for treating ulcerative colitis and relates to the medicament for treating colitis. The medicament is prepared by selecting the following raw materials by mass: 3 to 5g of synthetic bovine bezoar, 1.5 to 2.5g of borneol, 19 to 27g of pearl, 19 to 27g of ivory flakes, 88 to 100g of natural indigo and 13 to 19g of wall spider, grinding the raw materials are into powder, passing the power through a screen, and mixing the power to form mixed powder A; mixing 40,000 to 80,000 units of gentamicin and 30 to 50 ml of metronidazole solution to form gentamicin-metronidazole solution, and dissolving 1 percent of the mixed powder A into the gentamicin-metronidazole solution. The medicament has the advantages that: the medicament treats the ulcerative colitis and proctitis by a clysis method. The medicament can directly reach affected parts, can improve local blood concentration in intestines, avoids first-pass effect of liver, prevents or reduces damage of medicament to the liver and damage of digestive juice of stomach and intestines, and digestive enzyme to the medicament, and gives full play to availability of the medicament. The medicament also has the advantages of addressing of symptoms and root causes, rapid medicinal effect, safety, reliability and good curative effect. 156 clinical tests show that the effective rate of the medicament reaches 100 percent.

Description

Technical field: [0001] The present invention relates to a medicine, further to a medicine for treating colitis, especially a traditional Chinese medicine or a mixture of Chinese and western medicines for treating ulcerative colitis. Background technique: [0002] Ulcerative colitis, also known as chronic nonspecific ulcerative colitis, is mostly located in the rectum and sigmoid colon, and can also spread to the descending colon or even the entire colon. The whole clinical symptoms are diarrhea, pus and blood in the stool, abdominal pain and tenesmus. Modern medicine believes that the abnormality of autoimmune cells leads to the destruction of mucous membranes, or the disturbance of cerebral cortex and autonomic nerve dysfunction due to mental factors, resulting in intestinal hypermotility, spasm and contraction of intestinal vascular smooth muscle, tissue ischemia, and capillary permeability Increase, thereby forming inflammation, erosion and ulcer of intestinal mucosa. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/19A61K36/70A61K36/315A61K36/756A61K9/48A61K9/14A61K9/02A61K9/08A61K9/10A61P1/04A61K31/4164A61K31/7036A61K31/045A61K31/4375A61K35/32A61K35/413A61K35/56A61K35/64
Inventor 周景梅赵新运刘建方李青春
Owner 周景梅
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products