A method for controlling transmit power of a node in wireless network, such as, e.g., an ad-hoc wireless network operating in accordance with a carrier sense multiple access (CSMA) protocol and where asymmetrical radio links may exist. During a request to send (RTS) and clear to send (CTS) exchange between a first node and a second node, both a request to send (RTS) packet and a probing request to send (PrRTS) packet are transmitted from the first node to the second node. The transmit power and data rate of the PrRTS packet may be different from the transmit power and data rate of the RTS packet. In response, the second node returns a CTS packet that includes a signal to noise ratio (SNR) for both the RTS packet and the PrRTS packet. A correction factor for data transmit power is then computed based in part on both the SNR for the RTS and the SNR for the PrRTS, and a data packet is thereafter transmitted at a power level that has been modified in accordance with the correction factor. The correction factor may further aid the estimation of the signal-to-noise-and-interference ratio (S / (N+I)) at a receiving node, which enables a sending node either to overcome the interference by adjusting the transmit power or avoid the interference by not accessing the channel until it hears the node again.