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Thickened beverages for dysphagia

a beverage composition and thickening technology, applied in the direction of drug compositions, liquid transfer devices, therapy, etc., can solve the problems of swallowing discomfort, swallowing difficulty, inability to swallow,

Inactive Publication Date: 2011-06-09
SIMPLY THICK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

"The invention is a treatment for patients with dysphagia who also have other diseases or injuries. It involves using a thickener to make liquid foods easier for patients to swallow. The treatment also includes providing pre-thickened liquid foods with improved taste and appearance to encourage greater food consumption. The invention also includes a process for diagnosing and managing dysphagia using a consistent thickening system in both radiological compounds and the thickened liquid foods. The medical facility includes x-ray fluoroscopy facilities operated with radiological compounds and thickened liquid foods prepared in a consistent way. The invention also includes a process for producing homogeneously stable single phase thickened aqueous based beverages."

Problems solved by technology

Swallowing problems in humans include difficulty in swallowing, inability to swallow, and discomfort in swallowing.
People with dysphagia generally lack proper muscle control and coordination to properly seal the windpipe or they lack the ability to properly propel the entire bolus of food and / or beverage to the stomach.
If this condition goes unnoticed, sufferers are prone to foodstuff(s) and beverages going into the sufferer's lungs rather than being routed properly to their stomach.
When routing to the lungs occurs, the patient sufferer is at increased risk for growing unhealthy bacteria in the lungs which raises the prospect of aspiration pneumonia (with its accompanying attendant risks and hospitalization) and / or even fatal asphyxiation.
Powders have serious problems in that they do not disperse well, leave powder clumps, do not thicken many beverages, and will continue to thicken over time after mixing.
In addition, unfortunately, starch also has several serious inherent problems that limit its usefulness in the management of dysphagia and / or limits its suitability to be used by those with dysphagia and other diseases.
It adds calories to diets, and is thereby unsuitable for use with those who are on calorie restrictions, such as the morbidly obese.
Starch consumption elevates blood sugars and can not be easily used by diabetics.
Starch contains gluten that makes it unsuitable for those with celiac's disease.
Ketogenic diets, which control epileptic seizures by limiting digestible carbohydrate consumption also are inappropriate for starch thickeners.
Finally, the palatability of starch thickened beverages is poor, “Texture and Flavor Characteristics of Beverages Containing Commercial Thickening Agents for Dysphagia Diets”, V. Lotong, Journal of Food Science, Vol. 68, Nr.
Patients have long complained of the poor appearance and taste of beverages prepared with starch and are inclined to resist drinking beverages.
This can be especially problematic with patients of a young age or who have concomitant dementia or other impairment of cognitive communications.

Method used

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  • Thickened beverages for dysphagia
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  • Thickened beverages for dysphagia

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0089]A ready-to-consume pre-thickened type of thickened liquid food was prepared with xanthan gum and compared to a commercially available ready-to-consume pre-thickened non-xanthan gum beverage to demonstrate the improvements in calorie counts and carbohydrate content of the xanthan gum composition.

[0090]In that regard, a thickened water was prepared to honey consistency with xanthan gum. 7 g of Keltrol T from CP Kelco was added approximately 250 mL of hot tap water (about 115° Fahrenheit) while mixing with an electric hand mixer with a whisk attachment. The mixing was stopped after approximately 2 minutes and the mixture was added to enough hot tap water to bring the total weight to 1080 g. in a stand mixer with a whisk attachment. The beverage was mixed for approximately another 15 minutes to ensure complete dissolution. The mixture was packed in both a glass jar and in a plastic bag. Using standard dietary methods, it was found that an 8 oz serving of the beverage of this examp...

example 2

[0091]A xanthan gum thickener concentrate was prepared and its affect on water was compared to 2 commercially available starch products in 8 oz of water to show the reduction in calories and carbohydrate content. The concentrate was composed of 3.75% water, 0.5% citric acid, 0.1% sodium benzoate, and 0.1% potassium sorbate. The concentrate was heat processed for stability and stored in 10 g and 25 g foil packets. One 10 g packet was added per 4 oz of water for nectar consistency and one 25 g packet was added per 4 oz of water for honey consistency. For comparison, data were also collected from commercially available thickener powders known as ThickenUp from Novartis Nutrition, Minneapolis, Minn. and Thick-It from Precision Foods, St. Louis, Mo., USA.

Nectar ConsistencyHoney ConsistencyThickenerCarbohydrateCaloriesCarbohydrateCaloriesXanthan g 01 g 5ConcentrateThicken Up10.3 g4012 g45Thick-It10.5 g5317.5 g88

example 3

[0092]Example 3 demonstrates the utility of a thickener system used for both liquid diagnostic compositions and liquid foods. A thickener concentrate of 3.75% xanthan gum was prepared with a preservative system of 0.25% citric acid, 0.1% sodium benzoate, and 0.1% potassium sorbate. The solution was packaged in foil packets of approximately 25 g and heat pasteurized for shelf stability. Approximately 6 months later, one 25 g packet of the concentrate thickener was added to 12 oz of a liquid barium sulfate suspension suitable for a modified barium swallow, Liquid E-Z-Paque from E-Z-EM Canada, Inc. The concentrate was also added to commercially available apple juice at a rate of one 25 g packet per 4 oz. of juice. Both solutions were deemed to be of honey consistency. The data are presented in the table below.

100 rpm20 rpm5 rpmLiquid E-Z-Paque450 cP1465 cP4220 cPApple Juice415 cP1550 cP4860 cPcP = centipoise

[0093]The close agreement of viscosity at three different spindle speeds confir...

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Abstract

The present invention relates to thickened beverage compositions. More particularly the invention relates to beverage compositions thickened for the management of dysphagia. More particularly this invention relates to the production of thickened beverages by a dispensing machine that is also capable of dispensing non-thickened beverages.

Description

[0001]This application is a divisional of U.S. non-provisional application Ser. No. 10 / 542,506, filed Jul. 15, 2005, which is the United States national stage filing of PCT / US04 / 02795, filed Jan. 31, 2004 which claims the individual and collective benefit of U.S. provisional application Ser. No. 60 / 444,079 filed Jan. 31, 2003, U.S. provisional patent application Ser. No. 60 / 443,941 filed Jan. 31, 2003, U.S. provisional patent application Ser. No. 60 / 444,080 filed Jan. 31, 2003 and U.S. provisional patent application Ser. No. 60 / 444,082 filed Jan. 31, 2003 each and all of which are incorporated herein in their entirety by reference.FIELD OF THE INVENTION[0002]This invention relates to thickened beverage compositions. More particularly this invention relates to enhanced thickened beverage compositions comprising xanthan gum which may be effectively administered to living humans to overcome a human swallowing difficulty.BACKGROUND OF THE INVENTION[0003]Swallowing problems in humans inc...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K51/00A23K1/18B65D85/00B67D7/74A23L2/02A23L2/52A23L29/20A61KA61K9/08A61K47/36A61K49/00A61K49/04A61P1/00A61P1/06
CPCA23L1/054A23L1/30A23L2/02A23L2/52A23V2002/00A61K9/0095A61K49/0409A61K49/0404A61K31/736A23V2200/242A23V2250/5086A23L29/269A23L33/10A61P1/00A61P1/06Y02A50/30
Inventor HOLAHAN, JOHN L.
Owner SIMPLY THICK
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