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Zinc-titanium composite surface osteogenesis promoting implant and preparation method thereof

A composite surface and implant technology, applied in prosthesis, coating, medical science, etc., can solve the problem of increasing the surface roughness or osteocompatibility of implants, no improvement in bone loss in osteoporosis, and difficult processes. problems such as chemicalization, to achieve the effect of less exposed foreign body sensation, promote differentiation and value-added, and improve stability

Pending Publication Date: 2021-07-23
湖南华锐科技集团股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, both physical and chemical methods only increase the roughness or osteocompatibility of the implant surface, and do not improve the bone loss problem of osteoporosis itself.
Although biochemical methods have a certain bone-promoting effect, the process of grafting biomacromolecules is not easy to industrialize, and the product has a short shelf life.

Method used

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  • Zinc-titanium composite surface osteogenesis promoting implant and preparation method thereof
  • Zinc-titanium composite surface osteogenesis promoting implant and preparation method thereof

Examples

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preparation example Construction

[0030] In an embodiment of the present invention, a zinc-titanium composite surface promotes bone implant and its preparation method comprises the following steps:

[0031] The surface of pure titanium or titanium alloy rods with a diameter of 9-20mm is polished, sandblasted and acid-etched sequentially to obtain pretreated pure titanium or titanium alloy rods; the zinc alloy rods with a diameter of 11-40mm are perforated, And polish and polish the inner wall after perforation to form a zinc alloy pipe with an outer diameter of 11-40mm and a wall thickness of 1-10mm; after preheating the zinc alloy pipe with an outer diameter of 11-40mm and a wall thickness of 1-10mm, After the pipe is heated, the diameter becomes larger and inserted into the pretreated pure titanium or titanium alloy rod. After the temperature drops to room temperature, the zinc alloy pipe shrinks when it is cold, and forms a tight fixation with the pure titanium or titanium alloy rod to form zinc-titanium Ro...

Embodiment 1

[0034] The surface of a pure titanium rod with a diameter of 9 mm is sequentially subjected to grinding, sandblasting, and acid etching to obtain a pretreated pure titanium rod. A zinc alloy rod with a diameter of 11 mm is perforated, and the inner wall after the perforation is polished to form a zinc alloy pipe with an outer diameter of 11 mm and a wall thickness of 1 mm. After preheating the zinc alloy pipe with an outer diameter of 11mm and a wall thickness of 1mm, put it into the pretreated pure titanium rod while the diameter of the zinc alloy pipe becomes larger after being heated. After the temperature drops to room temperature, the zinc alloy pipe shrinks when it is cold. , and form a tight fixation with pure titanium rods to form zinc-titanium rods. The assembled zinc-titanium rods undergo 2 passes of hot swaging and 2 passes of cold swaging to form composite zinc-titanium rods with a diameter of 4mm. The composite zinc-titanium bar is mechanically turned into an emb...

Embodiment 2

[0036] The surface of a titanium alloy rod with a diameter of 20 mm is sequentially subjected to grinding, sandblasting, and acid etching to obtain a pretreated titanium alloy rod. A zinc alloy rod with a diameter of 40mm is perforated, and the inner wall after the perforation is polished to form a zinc alloy pipe with an outer diameter of 40mm and a wall thickness of 10mm. After preheating the zinc alloy pipe with an outer diameter of 40mm and a wall thickness of 10mm, put it into the pretreated titanium alloy rod while the diameter of the zinc alloy pipe becomes larger after being heated. After the temperature drops to room temperature, the zinc alloy pipe shrinks when it is cold. , and form a tight fixation with titanium alloy rods to form zinc-titanium rods. The assembled zinc-titanium rods undergo 4 passes of hot swaging and 8 passes of cold swaging to form composite zinc-titanium rods with a diameter of 10 mm. The composite zinc-titanium bar is mechanically turned into ...

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Abstract

The invention relates to the technical field of orthopedic implant materials, and particularly provides a zinc-titanium composite surface osteogenesis promoting implant and a preparation method thereof. The preparation method comprises the following steps: carrying out polishing, sand blasting and acid corrosion treatment on a pure titanium or titanium alloy bar to obtain a pretreated pure titanium or titanium alloy bar; after a zinc alloy bar is perforated, polishing the inner wall of the zinc alloy bar to obtain a zinc alloy pipe; preheating the zinc alloy pipe, putting the pure titanium or titanium alloy bar into the preheated zinc alloy pipe, and obtaining a zinc-titanium bar; and performing multi-pass rotary swaging treatment on the zinc-titanium bar to obtain a zinc-titanium composite bar, and turning the zinc-titanium composite bar to obtain the zinc-titanium composite surface osteogenesis promoting implant with embedded threads and fixing holes. The bone implant provided by the invention is high in overall structural stability and small in exposed foreign body sensation, and can be widely applied to orthopedic implant materials.

Description

technical field [0001] The invention relates to the technical field of orthopedic implant materials, and specifically provides a zinc-titanium composite surface-promoting bone implant and a preparation method thereof. Background technique [0002] Osteoporosis is a systemic disease that can lead to gradual decrease in bone mass, decrease in bone density and destruction of bone microstructure throughout the body, which in turn leads to increased bone fragility and high susceptibility to fracture in patients. The pathological factors leading to osteoporosis can be summarized as the destruction of bone balance established by osteoclasts and osteoblasts, and the bone depression formed by osteoclast resorption cannot be filled by new bone formed by osteoblasts, that is, new bone mass Decreased overall bone mass occurs when less bone mass is resorbed. For the osteoporosis of the bone tissue around the teeth, the fixation force of the teeth will be reduced, and it is easy to fall ...

Claims

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Application Information

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IPC IPC(8): A61L27/06A61L27/30A61L27/50C22F1/16C22F1/18
CPCA61L27/06A61L27/306A61L27/50C22F1/165C22F1/183A61L2430/12
Inventor 宋坤苏文刘江
Owner 湖南华锐科技集团股份有限公司
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