Medical titanium alloy surface coating and preparation method thereof

Abstract

The invention discloses a medical titanium alloy surface coating and a preparation method thereof. The titanium alloy surface coating is Ti-27Nb-6Zr-5Mo alloy surface Ta or Ta-Cu-Zn composite coating.A Ti-27Nb-6Zr-5Mo alloy surface is polished; and a nano oxidation tube is prepared on the alloy surface with an anodizing method, then a layer including tantalum (Ta), copper (Cu) and Zinc (Zn) is sprayed to the surface of the nano tube with the plasma spraying technology, and the composite bio-coating is prepared. Medical titanium alloys are compared, the nano oxidation tube is attached to the alloy surface, Ta and TaCuZn are sprayed to the surface of the oxidation tube, the corrosion resistance, the biological activity and the antibacterial performance are improved, the bio-activity and thebonding strength of the coating and an alloy substrate can be improved through an intermediate nano oxidation layer, the corrosion resistance of the coating can be improved due to Ta on the surface,and the bacterial infection resistance of the medical titanium alloys can be improved through a trace of continuously-separated Cu and Zn ions in the coating. The novel coating material is beneficialto solving the problems that an existing bone implant material is poor in bio-activity, insufficient in corrosion resistance and antibacterial performance and the like.

Description

technical field [0001] The invention belongs to the technical field of surface modification of medical titanium alloy materials, in particular to a biomedical coating material and a preparation method for improving the biological activity, corrosion resistance and antibacterial properties of a titanium alloy substrate. Background technique [0002] Titanium and its alloys are widely used in industrial and biomedical fields, especially in dentistry and orthopedic medicine, due to their good mechanical and biological properties. Although the implanted titanium alloy, as the key material to bear the load, has the mechanical compatibility with the human bone, its surface properties still cannot fully adapt to the complex physiological environment of the human body. On the one hand, as a biologically inert material, titanium alloy implants have poor biological activity and cannot form strong chemical osseointegration with bone, but can only form mechanical bonds with tissues. Aft...

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Problems solved by technology

Due to the high surface energy and special structural properties of the nano-oxide layer structure on the surface of titanium alloy, it can effectively promote the growth of bone-like substances, but due to the 2 Nanotubes and cell membranes are negatively charged, and cell adhesion is limited, which further affects cell proliferation and differentiation, resulting in the nanotube modification technology on the surface of titanium implants being greatly limited in clinical applications. Therefore, in nanotube Prepare a coating with excellent biological activity and antibacterial properties on the surface to promote cell adsorption

However, during the long-term implantation process, due to the poor bonding of the active coating to the substrate, the coating on the surface of the titanium alloy will peel off, which will induce inflammation and bring secondary pain to the patient.

[0004] In addition, the corrosion resistance of titanium alloy is poor, and the antibacterial infection ability is insufficient, so there is a risk of postoperative infection

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