Method of preparing stabilized sulforaphene

Abstract

The invention provides a method of preparing stabilized sulforaphene and belongs to the technical field of separation and purification of natural products. The method includes the steps of with defatted carmine radish seed powder as a raw material, preparing sulforaphene; preparing anhydrous auxiliary material powder; preparing a sulforaphene dispersion substance; and preparing the stabilized sulforaphene, which can reach 12-14 months in shelf life without degradation. In the method, influences on the sulforaphene due to external factors, such as illumination, temperature and aerobic environment, etc., are comprehensively considered, and measurements of dark condition, low temperature, negative pressure and deoxygenation and nitrogen filling are employed for eliminating the adverse factors causing degradation of the sulforaphene as far as possible, thereby significantly improving stability of the sulforaphene. All of the production devices are industrial devices, so that the method has simple production conditions and convenient operations, and is suitable for large-scale production. The production process has no generation of waste gas, waste water and solid wastes and is a typical green production process, so that the method is easy to promote and apply. The produced stabilized sulforaphene can be widely applied to the fields such as medicine research and development, food and health care products, etc.

Description

1. Technical field [0001] The invention belongs to the technical field of separation and purification of natural products, and in particular relates to a method for preparing stabilized radishone. 2. Background technology [0002] Radixin is also known as radishin, radishin, etc., and its molecular formula is C 6 h 9 NOS 2 , the system name is (E) 4-isothiocyanato-1-(methylsulfinyl)-1-butene, which is a syrupy yellow liquid at room temperature, soluble in water, methanol, ethanol, chloroform , ether and other solvents. Relevant studies have shown that rapathin has strong biological activities in anti-oxidation, anti-virus, lowering blood pressure, anti-platelet aggregation, promoting digestion, preventing cardiovascular diseases, etc. With obvious blocking effect, it is a natural active substance with market potential and economic value. However, due to the influence of temperature, light, solvent and other factors, radhamin degrades rapidly during production, transport...

AI Technical Summary

Problems solved by technology

The main disadvantages of this method are: ① adding radhamin to the prepared membrane material aqueous solution, and radhamin is extremely unstable in the aqueous solution and begins to degrade within a few minutes; ② the inlet air temperature reaches 180°C when spray drying At this temperature, the degradation rate of radishin is faster; ③Compared with the radishin without microencapsulation, although the prepared microcapsule-embedded radish can effectively isolate oxygen, because the radishin in ① and ② Has obviously degraded, therefore, this method is difficult to prepare high-purity radishone product

The disadvantages of this method are: ① Dehydration treatment of polyethylene glycol and vegetable oil is not carried out, and radishin will be degraded even if it contacts with a small amount of water, resulting in a decrease in its stability; , while radishin will change and accelerate its decomposition under light, which also leads to a decrease in its stability; ③The result obtained in this patent is: in 360 days, the degradation rate of radishin at -80°C to 120°C was significantly reduced to that of the control group 20.3%~35.8% of

That is to say, through the preservation method published in this patent, radishin is still degrading, even at an extreme temperature of -80°C, which shows that it does not have sufficient stability, and the degradation products of radishin will have harmful effects on the human body. Produce a variety of toxic and side effects, therefore, the radishin preserved by this method can not be used in medicine or food industry