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A polyetheretherketone/nanometer hydroxyapatite dental implant and its manufacturing method

A technology of nano-hydroxyapatite and polyether ether ketone, which is applied in prosthetics, medical science, coatings, etc., can solve problems such as the unreliable bonding interface between the neck of the surface structure design and the gingival tissue, and implantation failure. Avoid implant loosening, improve the success rate, and promote the effect of attachment growth

Inactive Publication Date: 2017-05-31
SICHUAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition to the high elastic modulus of the existing dental implants, the loosening of the implants provides a pathway for bacterial invasion, and the unreliable bonding interface between the neck and the gum tissue caused by improper surface structure design also provides a pathway for bacterial invasion, and bacteria multiply and accumulate. , which will eventually cause the implant to fail

Method used

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  • A polyetheretherketone/nanometer hydroxyapatite dental implant and its manufacturing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] In this example, the preparation method of polyetheretherketone / nano-hydroxyapatite dental implant is as follows:

[0034] (1) The polyetheretherketone powder and nano-hydroxyapatite powder are mixed according to the mass ratio of 1:10 by mechanical blending method to obtain the polyetheretherketone / nano-hydroxyapatite composite material, and the molding machine is used Process polyetheretherketone / nano-hydroxyapatite composite materials into dental implant-like blanks;

[0035] (2) Clean the green body obtained in step (1) ultrasonically for 5 minutes in ethanol and then vacuum-dry it. Soak the neck of the green body after cleaning and drying in a fibronectin solution with a concentration of 5 μg / mL for 0.5 h and take it out. The green body after soaking treatment has an energy density of 250mJ / cm 2 0.5h of ultraviolet light irradiation, after the end of the irradiation, the surface of the body was cleaned with deionized water and dried naturally to obtain a body with...

Embodiment 2

[0040] In this example, the preparation method of polyetheretherketone / nano-hydroxyapatite dental implant is as follows:

[0041] (1) The polyetheretherketone powder and nano-hydroxyapatite powder are mixed according to the mass ratio of 4:10 and fully mixed by mechanical blending method to obtain the polyetheretherketone / nano-hydroxyapatite composite material, which is molded by a compression molding machine Process polyetheretherketone / nano-hydroxyapatite composite materials into dental implant-like blanks;

[0042] (3) immerse the green body root that step (2) obtains and be that concentration is 13g / L in the decafluoronaphthalene solution etch 0.7 hour, make the root portion surface of described green body form micron-scale porous structure, then the etched The root of the green body is placed in nano-hydroxyapatite powder to adhere a layer of nano-hydroxyapatite particles, so that the surface of the root forms a micro-porous-nano-protruded multi-level microstructure;

[...

Embodiment 3

[0046] In this example, the preparation method of polyetheretherketone / nano-hydroxyapatite dental implant is as follows:

[0047] (1) The polyetheretherketone powder and nano-hydroxyapatite powder are mixed according to the mass ratio of 7:10 by mechanical blending method to obtain the polyetheretherketone / nano-hydroxyapatite composite material, and the molding machine is used Process polyetheretherketone / nano-hydroxyapatite composite materials into dental implant-like blanks;

[0048] (2) Ultrasonic cleaning the green body obtained in step (1) in ethanol for 10 minutes and then vacuum-drying, soaking the neck of the green body after cleaning and drying in a fibronectin solution with a concentration of 60 μg / mL for 1 hour, taking out the neck, and then soaking The green body after treatment has an energy density of 350mJ / cm 2 1h of ultraviolet light irradiation, after the irradiation, the body surface was cleaned with deionized water and dried naturally to obtain a body with ...

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Abstract

Disclosed is a polyether ether ketone / nano-hydroxyapatite dental implant consisting of a neck (1) and a root (2), the neck (1) of which is grafted with a fibronectin or a basic fibroblast growth factor, and the surface of the root (2) of which is a micron porous-nano bulge multistage microstructure. The method for manufacturing the dental implant comprises: preparing a workblank; grafting the fibronectin or basic fibroblast growth factor onto the surface of the neck (1) of the workblank; the root (2) of the workblank is immersed in a decafluoronaphthalene solution for etching, and then put into nano-hydroxyapatite powder to adhere a layer of nano-hydroxyapatite particles; and the workblank is immersed in the nano-hydroxyapatite slurry doped with Ag+ or Zn2+. The elastic modulus of the dental implant matches a human bone tissue, and the dental implant has a high biological activity and continuous antibacterial capacity, thereby improving the long-term success rate thereof.

Description

technical field [0001] The invention belongs to the field of dental implants, and relates to a composite material dental implant and a manufacturing method thereof. Background technique [0002] At present, the commonly used dental implant systems at home and abroad all use pure titanium or titanium alloy as the base material of the dental implant, and the surface of the implant root is also processed into micropores or coated with apatite coating, and its clinical short-term restoration effect is remarkable , the five-year success rate can reach 90%, but the long-term success rate is still low, and the failure rate of clinical implantation in 10 years is as high as 35%. An important factor causing unsatisfactory long-term effects is that the elastic modulus of titanium implant materials (>110GPa) is much higher than that of human jawbone, which causes long-term stress shielding and stress stimulation, resulting in the loss of bone tissue around the implant. Absorption a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/42A61L27/12A61L27/18A61L27/54A61L27/56A61L27/34
CPCA61L27/12A61L27/18A61L27/42A61L27/54
Inventor 张利涂英李玉宝
Owner SICHUAN UNIV
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