Compound selenium Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof

Abstract

The invention discloses a compound selenium Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. The Chinese medicinal composition comprises the following extract components of Chinese herb medicines in part by weight: 10 to 85 parts of natto extract, 0.5 to 6 parts of polysaccharide selenate, 15 to 90 parts of kudzuvine root, 20 to 95 parts of grape seed extract, 20 to 90 parts of green tea extract, 25 to 110 parts of sea buckthorn extract, 25 to 95 parts of fructus crataegi extract, 10 to 90 parts of notoginseng root extract, 10 to 95 parts of ginkgo biloba extract and 25 to 100 parts of garlic extract. The Chinese medicinal composition is prepared from the various components according to the principle of promoting blood circulation and removing blood stasis, resolving phlegm, dissolving emboli and decreasing blood-lipid, removing toxin, purifying blood, repairing vessels, and promoting qi circulation and removing obstruction in the collaterals, so that the clinical effect is obvious, and the effective rate is high; and moreover, the Chinese medicinal composition is prepared from pure natural herbal medicines, does not have toxic or side effects, does not cause adverse reaction and is safe. The preparation method for the compound selenium Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases is simple in process; the properties of the composition are stable and reliable; the production efficiency is high; and the production cost is low.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a compound selenium-enriched traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. Background technique [0002] The so-called cardiovascular and cerebrovascular diseases are collectively referred to as diseases of the heart and cerebrovascular diseases. At present, cardiovascular and cerebrovascular diseases have become the diseases with high morbidity, high disability rate, high mortality rate, high recurrence rate, high medical expenses, and many complications (often called "five highs and one high") in China. Cardiovascular and cerebrovascular diseases mainly refer to 11 diseases such as coronary heart disease, myocardial infarction, cerebral thrombosis, and high blood pressure. Caused by increased blood pressure and microcirculation disorders; blood lipids accumulat...

AI Technical Summary

Problems solved by technology

[0004] 1. In the process of treating acute cardiovascular and cerebrovascular diseases such as myocardial infarction, cerebral infarction, and cerebral hemorrhage, Western medicine mostly uses surgical treatment, that is, stents, bypass, craniotomy, etc. This is the fastest and most dangerous method, but often occurs Vascular restenosis, re-occlusion, and re-injury; and most patients with cardiovascular and cerebrovascular diseases are middle-aged and elderly people, with low body immunity and slow recovery after procedures, which can easily cause post-operative complications, and the average mortality rate within five years has increased significantly. the price is also expensive

The second method commonly used in western medicine is aspirin and warfarin. However, western medicine has a lot of side effects, and many patients need to take medicine for life, which brings great harm to organs such as intestines, stomach, liver, kidney, etc., leading to the decline of body functions, which in turn leads to a series of diseases

The third method is to use lipid-lowering drugs to control the risk factors of cardiovascular and cerebrovascular diseases—hyperlipidemia. Commonly used lipid-lowering drugs mainly include statins, fibrates, nicotinic acid and bile acid sting mixture. Cholesterol and high lipoprotein have obvious curative effects, but long-term use will cause many side effects, such as abdominal distension, diarrhea, headache, insomnia, gastrointestinal reactions, elevated serum transaminases, and elevated blood sugar, etc. The drug price is also expensive

Fourth, the use of biological kinases has developed another therapeutic approach for western medicine, but the hormone-enzyme thrombolytic drugs represented by urokinase have large side effects, short half-life in the body, are not easy to absorb, and are expensive

Although traditional Chinese medicine prescriptions can play a certain role in reducing fat, blood pressure, and cholesterol during the treatment process, and can also improve the patient's immunity and disease resistance to a certain extent, but due to traditional Chinese medicine theory and traditional Chinese medicine The limitations of prescriptions are often imprisoned by these methods and cannot escape from the existing TCM theories and TCM prescriptions. The main effect is still to dilate blood vessels.

And because the real cause of cardiovascular and cerebrovascular diseases is the deterioration of the blood environment, the reduction of blood quality, the garbage in the blood accumulates on the blood vessel wall, resulting in atherosclerosis, thinning, embrittlement, and loss of elasticity of the blood vessel wall. Etc. Therefore, the curative effect of existing traditional Chinese medicine prescription is not ideal, and concrete performance is in: 1. All use the whole raw material of traditional Chinese medicine to be used as medicine, do not combine modern Chinese medicine pharmacology, make full use of the active ingredient in the Chinese medicine extract, effect is not satisfactory ; 2 The compatibility of prescriptions is not reasonable

3. Drugs that have not broken through the shackles of the predecessors, drugs that have not been used by the predecessors, and drugs that have been proved to be beneficial by modern research are not included

[0006] Although western medicine and traditional Chinese medicine in the modern medical circle have made many efforts in various aspects such as prevention and clinical treatment, and have made remarkable achievements, they have not fundamentally changed the current situation that cardiovascular and cerebrovascular diseases endanger human health.

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