Traditional Chinese medicine combination for treating acute granulocyte AML-M4 leukemia

Abstract

The invention discloses a traditional Chinese medicine combination for treating acute granulocyte AML-M4 leukemia, comprising the following compositions: 15-25g of root of rehmannia, 8-16g of tree peony bark, 4-8g of fired powder liquorice with honey, 18-32g of Ophiorrhiza pumila, 14-20g of rhizoma imperatae, 18-28g of ligustrum lucidum, 14-28g of herba cistanche, 4-8g of aweto, 12-24g of brown lily, 10-20g of radix patriniae heterophylla and 11-21g of smilax glabra. The medicament treats concrete AML-M4 acute granulocytic leukemia with pertinence, selectively inhibits and kills immature cells, induces apoptosis of leukemia cells, has stronger pertinence and higher curative effect and has the effects of promoting differentiation and maturation of the leukemia cells, regulating qi and blood, strengthening the immunologic function, promoting recovery of marrow normal hematopoietic function, reducing reversion, preventing production of drug resistance, reducing the toxic and side effects of chemotherapy and improving the physique.

Description

technical field [0001] The invention relates to a medicine for treating leukemia, in particular to a traditional Chinese medicine composition for treating acute granulocytic AML-M4 leukemia. Background technique [0002] Leukemia is A malignant clonal disease of hematopoietic stem cells, characterized by the diffuse proliferation of abnormal white blood cells (leukemic cells) in the bone marrow to replace normal bone marrow tissue and invade the surrounding blood, resulting in quantitative and qualitative changes in the white blood cells in the peripheral blood. The number of white blood cells in the blood is often significantly increased, but sometimes it can be normal or even decreased. Leukemic cells can extensively infiltrate various tissues and organs throughout the body, such as the liver, spleen, and lymph nodes, and often cause anemia and hemorrhage. [0003] According to the statistics of the Ministry of Health, in 2009, the annual incidence rate of leukemia in m...

AI Technical Summary

Problems solved by technology

However, this method has great side effects, such as killing and inhibiting normal hematopoietic stem cells, leading to anemia and bleeding, suppressing normal immune function, reducing body immunity, and easily merging with various infections, damaging the gastrointestinal mucosa, leading to anorexia, nausea, and vomiting. Affects heart, liver and kidney functions. No matter how high the dose is, it is impossible to completely kill the white blood cells in the body, and the residual leukemia cells are the root cause of disease recurrence.

This not only brings great pain to the patients themselves, but also causes heavy mental burden and economic losses to their families and society.