Gel coating suite capable of preventing infection and leakage after eye surgery

Abstract

The invention provides a gel coating suite capable of preventing adverse events such as wound infection, and the like after an eye surgery, comprising: a fluid component in a buffer solution which includes lysine, polylysine or polyethyleneglycol multi-branch isomer and has a pH value between 3 and 12 in a first container; and a solid component of a group formed by polytrimethylene carbonate, polylactic acid, polyethyleneglycol, polyethyleneglycol multi-branch isomer, glutin, polyurethane, gelatin, polyphosphate ester, polyglycolic acid, as well as copolymer and blend thereof in a second container. When the fluid component and the solid component are mixed, the gel is formed and directly coated to the parts for preventing the infection and the leakage after the eye surgery.

Description

technical field [0001] The invention relates to the field of medical instruments, in particular to a surgical kit for hemostasis and anti-seepage. technical background [0002] Ophthalmic surgery and trauma will form bloody wounds, during which a large amount of fluid will be lost, and preventive measures need to be taken in time. The use of biocompatible absorbable hemostatic materials on wounded surfaces is a common means of preventing infection, and there is an urgent need for hemostasis in surgery, trauma, first aid, and home self-rescue. It can be seen that providing a safe, effective, The importance of easy-to-use and low-cost hemostatic materials to human health. Hemorrhage is one of the common complications of cataract, glaucoma and vitreous surgery. Postoperative anterior chamber hemorrhage mostly occurs within 1 week after surgery, mostly from incision or iris blood vessel bleeding. Vitreous hemorrhage is often due to diabetes, retinal breaks, or secondary to low...

AI Technical Summary

Problems solved by technology

First of all, from the aspect of application, this hemostatic material is mainly limited to the hemostasis of skin or soft tissue wounds, and the hemostasis of tissues and organs in the deep part of the body cavity, especially the hemostasis under endoscopy (such as minimally invasive endoscopy, colonoscopy and laparoscopy). During operation) there is still lack of effective means; the second, from the preparation method, epichlorohydrin is a colorless oily liquid, toxic and anesthetic, so producing this product is unfavorable to the environment, and the production cost is also higher; the third, from In terms of hemostatic effect, because its water absorption is not strong enough, the water absorption rate is low, and the speed of water absorption is slow, the hemostatic effect is not ideal, especially for active bleeding. The viscosity of the gel is poor, so the clot formed after interacting with blood has poor adhesion to the tissue, and cannot effectively block the damaged tissue and blood vessels, thus affecting the effect of hemostasis; fifth, during active bleeding, The hemostatic powder is difficult to adhere to the bleeding site and is easily washed away by the blood flow. If the auxiliary material is pressed on the hemostatic powder, the auxiliary material is easily adhered by the blood clot, causing re-bleeding when the auxiliary material is uncovered

Therefore, it is not effective for active bleeding hemostasis

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