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Chinese medicine patch for treating cold and pain and method for producing the same

A production method and technology of traditional Chinese medicine paste, applied in the direction of medical formula, non-central analgesics, medical preparations containing active ingredients, etc., can solve the problems of patient safety, toxic and side effects, etc., and achieve short inclusion time and process conditions Easy to control and high product yield

Inactive Publication Date: 2010-03-31
TIANJIN ZHONGBAO PHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Generally, after a patient suffers from a cold, he is usually treated with medicaments, mostly oral medicines or injections, but both oral medicines and injections have toxic and side effects, and will produce a reaction through the first-pass effect of the liver and the release of the digestive tract, which will bring patients safe question

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1 (high dose)

[0013] The traditional Chinese medicine patch for treating colds and pains and the preparation method are as follows: notopterygium 10kg, fangfeng 10kg, and ginger 10kg.

[0014] Notopterygium, Fangfeng and ginger were taken in proportion, crushed and ground respectively, and after being homogenized by a micron homogenizer and a nano homogenizer, the particle size of each component was 100-200 μm.

[0015] After the quality inspection of the particle size, the ground raw materials were put into the colloid mill for CO 2 Supercritical extraction, adding β-cyclodextrin and appropriate amount of water, the weight ratio of raw material drug to β-cyclodextrin is 1:6. Grind the colloid mill evenly, keep the speed at 3000r / min, adjust the distance between the mills to 5 μm, continuously and slowly add an appropriate amount of ethanol-dissolved ingredients of the raw material drug, soak for 6 hours, refrigerate at 4°C for 24 hours, and vacuumize. Va...

Embodiment 2

[0019] Embodiment 2 (low dosage)

[0020] The traditional Chinese medicine patch for treating colds and pains and the preparation method are as follows: notopterygium 5kg, fangfeng 3kg, and ginger 3kg.

[0021] Notopterygium, Fangfeng and ginger were taken in proportion, crushed and ground respectively, and after being homogenized by a micron homogenizer and a nano homogenizer, the particle size of each component was 100-200 μm.

[0022] After the quality inspection of the particle size, the ground raw materials were put into the colloid mill for CO 2 Supercritical extraction, adding β-cyclodextrin and appropriate amount of water, the weight ratio of raw material drug to β-cyclodextrin is 1:6. Grind the colloid mill evenly, keep the speed at 3000r / min, adjust the distance between the mills to 5 μm, continuously and slowly add an appropriate amount of ethanol-dissolved ingredients of the raw material drug, soak for 6 hours, refrigerate at 4°C for 24 hours, and vacuumize. Vacu...

Embodiment 3

[0026] Embodiment 3 (medium dose)

[0027] The traditional Chinese medicine patch for treating colds and pains and the preparation method are as follows: Notopterygium 7.5kg, Fangfeng 6.5kg, and Ginger 6.5kg.

[0028] Notopterygium, Fangfeng and ginger were taken in proportion, crushed and ground respectively, and after being homogenized by a micron homogenizer and a nano homogenizer, the particle size of each component was 100-200 μm.

[0029] After the quality inspection of the particle size, the ground raw materials were put into the colloid mill for CO 2 Supercritical extraction, adding β-cyclodextrin and appropriate amount of water, the weight ratio of raw material drug to β-cyclodextrin is 1:6. Grind the colloid mill evenly, keep the speed at 3000r / min, adjust the distance between the mills to 5 μm, continuously and slowly add an appropriate amount of ethanol-dissolved ingredients of the raw material drug, soak for 6 hours, refrigerate at 4°C for 24 hours, and vacuumize...

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Abstract

The invention provides a Chinese medicine patch for treating cold and pain and a method for producing the same, and the invention contains the following components in proportion by weight: notopterygium root 5-10, windproof 3-10, ginger 3-10; the invention includes the steps of: proportionally mixing raw materials, grinding until particle diameter of each component is 100-200 mu m; using CO2 supercritical extraction, fractionating acquired distillates with a fractionating tower, mixing each component in the formula into nano medicinal pulp according to the formula proportionality through the nano dispersing apparatus, adding accelerating agent for percutaneous absorption and contact adhesive into the circular type low temperation drying coater, and after coating, executing shearing, quality test, packaging and then sending the product into warehouse. The invention uses a scientific method for processing and extracting medicinal materials, which are filled in the framework of the substrate, and the paster substrate has a good compatibility with skin, and is good for medicament molecule to pass; the medicament has the advantages of slow release, smooth and steady administration, small irritation without toxic and side effects, thereby resolving the problem that oral medication and injection have toxic and side effects for human body and preventing toxic and side effects of medicament taken orally.

Description

technical field [0001] The invention relates to a traditional Chinese medicine patch, in particular to a traditional Chinese medicine patch for treating colds and pains and a preparation method thereof. Background technique [0002] Flu is the most common frequently-occurring disease. Western medicine believes that colds are caused by viruses, and the main treatment methods are antiviral drugs, vaccines, and symptomatic antipyretic and analgesic drugs; it is generally believed that colds need a week to recover with or without treatment, and some people have even done statistics, and the results show that the effect of treatment The effect is equivalent to no treatment, or even worse than no treatment. Traditional Chinese medicine believes that a cold is caused by the invasion of exogenous pathogens and stagnation of internal dampness, and the treatment should start from the root cause. Generally, after a patient suffers from a cold, he is usually treated with medicaments, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/70A61K47/40A61K47/02A61P31/12A61P29/00
Inventor 梁秉文高惠明杨吉田
Owner TIANJIN ZHONGBAO PHARMACY
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