Veterinary five-flavored evergreen particle preparation method

Abstract

The invention relates to a veterinary five-flavored evergreen particle preparation method which includes the steps: 1 mixing sweet wormwood herbs with Chinese thorowax roots, and performing reflux extraction with water to obtain volatile oil, extracting solution A and sweet wormwood herb and Chinese thorowax root residues; 2 adding glycerol into the volatile oil, uniformly mixing the glycerol andthe volatile oil to obtain volatile oil and glycerol mixing solution; adding water into beta-cyclodextrin, heating and dissolving the beta-cyclodextrin to prepare beta-cyclodextrin water solution; slowly adding the volatile oil and glycerol mixing solution into the beta-cyclodextrin water solution, and adding alcohol after stirring, refrigeration, suction filtration and drying to prepare volatileoil inclusion particles; 3 adding lightyellow sophora roots, antifeverile dichroa roots and lalang grass rhizome into the sweet wormwood herb and Chinese thorowax root residues, performing extractionwith water twice, combining secondary extracting solution B and the extracting solution A, performing spray drying after concentration, sieving products and adding auxiliary material pellets to obtainmedicinal material particles; 4 uniformly mixing the volatile oil inclusion particles with the medicinal material particles. The products prepared by the method are small in volatile oil smell, highin content and stable in quality.

Description

technical field [0001] The invention belongs to the field of preparation of veterinary medicines, and in particular relates to a preparation method of veterinary Wuwei Changqing granules. Background technique [0002] Chicken coccidiosis is a disease caused by a variety of coccidia of the genus Eimeria parasitic in the intestinal tract of chickens. Cause huge economic losses, affect food safety at the same time, damage human health. Long-term large-dose use of antibiotics and chemical synthetic drugs to prevent and treat the disease is prone to produce toxic side effects and drug resistance, and also cause public safety problems such as drug residues; The alkaloids in it have the effect of inhibiting and killing coccidia, Bupleuri can clear away heat and detoxify, have antibacterial and anti-inflammatory effects, and the rhizome of Rhizoma Imperatae has hemostatic effect. The five flavors of medicine are compatible, and the Wuwei Changqing granule made of it has a good cura...

AI Technical Summary

Problems solved by technology

Because the volatile oil is easy to volatilize, oxidize and have poor stability, the traditional Chinese medicine granule preparation process, the volatile oil is easy to lose, resulting in difficult control of product quality, lower clinical effect, and obvious smell of volatile oil, which affects feed intake