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Compound gossypol acetate administer orally formulation

An oral preparation of gossypol acetate and the technology of gossypol acetate are applied in the field of medicine, can solve the problems of high price, large side effects, unsatisfactory effect and the like, and achieve the effects of being convenient to take, easy to carry, and improving bioavailability

Inactive Publication Date: 2008-08-27
刘德强
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0010] It can be seen from the above that the application of hormone products in the treatment of diseases such as uterine fibroids and endometriosis has large side effects, and it is difficult for patients to adhere to the treatment, and the cycle is long, the price is expensive, and the effect is not ideal.

Method used

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  • Compound gossypol acetate administer orally formulation

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Embodiment Construction

[0033] 1, the preparation method of compound gossypol acetate capsule

[0034] Prescription gossypol acetate 20g potassium chloride 250g vitamin B 1 10g

[0035] Vitamin B 6 10g. Starch 54.4g Dextrin 37.8g

[0036] A total of 1000 capsules were made, and each capsule contained 20mg of gossypol acetate

[0037] According to the prescription, the compound drugs such as gossypol acetate and the like are uniformly mixed, granulated, dried and granulated, and after passing the inspection, they are divided into empty capsules to obtain the product.

[0038] 2. The preparation method of compound gossypol acetate enteric-coated capsules

[0039] Prescription gossypol acetate 20g potassium chloride 250g vitamin B 1 10g

[0040] Vitamin B 6 10g. Starch 54.4g Dextrin 37.8g

[0041] A total of 1000 capsules were made, and each capsule contained 20mg of gossypol acetate

[0042] According to the prescription, the compound medicines such as gossypol acetate and the li...

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Abstract

The invention relates to a compound oral preparation containing gossypol acetate and other drugs. The compound oral preparation mainly contains gossypol acetate, potassium chloride, vitamin B1 and vitamin B6; and is available in the form of capsule, enteric-coated capsule, sustained-release capsule, soft capsule, oral liquid, tablet, dispersible tablet, enteric-coated tablet, sustained-release tablet or powder. The preparation has no bitter taste, high bioavailability and function for treating gynecological diseases such as essential uterine bleeding, hysteromyoma, menorrhagia and endometriosis.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to a compound oral dosage form containing gossypol acetate and other medicines for treating gynecological diseases, which is made into capsules, enteric-coated capsules or soft capsules or sustained-release capsules or oral liquids or dispersible tablets or enteric-coated tablets. Background technique [0002] The chemical name of gossypol acetate is: [0003] Acetic acid-2,2'bis[8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene] [0004] The structural formula is: [0005] [0006] Molecular formula: C 32 h 34 o 10 [0007] Molecular weight: 578.59 [0008] This compound is one of the main components of cottonseed, and it has been recorded in Chinese medicine literature that it has the effects of warming the kidney, tonifying deficiency, and stopping bleeding. A large number of domestic and foreign experts have confirmed that gossypol is an effective and safe dr...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K9/48A61K9/52A61K9/14A61K9/08A61K9/10A61K9/20A61K9/22A61K47/40A61K47/36A61K47/42A61K47/38A61K47/34A61K31/11A61K31/4415A61K31/51
Inventor 刘德强李英刘倩
Owner 刘德强
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