A luggage brake device includes a wheel and a control unit. The wheel includes positioning teeth, an engaging member, engaging teeth, a link axle, a link plate, a control wire. The control unit is disposed on a luggage body. The control unit includes a knob, a press button, a gear, a release block and a driving block connected with the control wire. Through the knob, the press button and the driving block of the control unit, the control wire is activated to link the engaging member with the engaging teeth to engage with the positioning teeth of the wheel so that the wheel is positioned. The present invention can be operated conveniently.