72 results about "Transcranial Electrical Stimulations" patented technology

Disclosed are devices and methods for detecting, preventing, and / or treating neurological disorders. These devices and methods utilize electrical stimulation, and comprise a unique concentric ring electrode component. The disclosed methods involve the positioning of multiple electrodes on the scalp of a mammal; monitoring the mammal's brain electrical patterns to identify the onset of a neurological event; identifying the location of the brain electrical patterns indicative of neurological event; and applying transcutaneous or transcranial electrical stimulation to the location of the neurological event to beneficially modify brain electrical patterns. The disclosed methods may be useful in the detection, prevention, and / or treatment of a variety of indications, such as epilepsy, Parkinson's Disease, Huntington's disease, Alzheimer's disease, depression, bipolar disorder, phobia, schizophrenia, multiple personality disorder, migraine or headache, concussion, attention deficit hyperactivity disorder, eating disorder, substance abuse, and anxiety. The disclosed methods may also be used in combination with other peripheral stimulation techniques.

Disclosed are devices and methods for detecting, preventing, and / or treating neurological disorders. These devices and methods utilize electrical stimulation, and comprise a unique concentric ring electrode component. The disclosed methods involve the positioning of multiple electrodes on the scalp of a mammal; monitoring the mammal's brain electrical patterns to identify the onset of a neurological event; identifying the location of the brain electrical patterns indicative of neurological event; and applying transcutaneous or transcranial electrical stimulation to the location of the neurological event to beneficially modify brain electrical patterns. The disclosed methods may be useful in the detection, prevention, and / or treatment of a variety of indications, such as epilepsy, Parkinson's Disease, Huntington's disease, Alzheimer's disease, depression, bipolar disorder, phobia, schizophrenia, multiple personality disorder, migraine or headache, concussion, attention deficit hyperactivity disorder, eating disorder, substance abuse, and anxiety. The disclosed methods may also be used in combination with other peripheral stimulation techniques.

A method of eliciting analgesia in a human subject by Transcranial Electrical Stimulation (TCES, herein “TES”) is provided. Electrodes secured to the skin of the subject's head at particular sites provide an electrical current that includes a direct current combined with rectangular AC current pulses delivered at a particular frequency of between 10 and 100 Hz. In an embodiment the total current transmitted, a sum of the DC component and a Mean Absolute Deviation (MAD) of the current pulses, has a value between 0.2 and 20 mA. The method is used to produce analgesia during perioperative period, surgery and the post-operative procedure. It can also be used for treating acute chronic pain and a wide variety of other conditions.

Systems, apparatuses, and methods for providing non-transcranial electrical stimuli to a biological subject may employ a support structure, at least one waveform generator, and at least a first electrode and a second electrode. The system can be sized and dimensioned to be worn on a head of the biological subject and operable to deliver non-transcranial electrical stimuli to at least one of the temporomandibular joints of the biological subject.

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for developing transcranial electrical stimulation protocols are disclosed. In one aspect, a method includes forming a first array of electrodes and optimizing a plurality of electrode parameters within the first array of electrodes to achieve a desired physiological response; identifying one or more electrodes within the optimized first array that have relatively low current compared to the remaining electrodes in the first array; removing the identified low current electrodes from the first array to form a second array of electrodes, wherein the number of electrodes in the second array is less than the number of electrodes in the first array and optimizing a plurality of electrode parameters with the second array of electrodes to achieve a desired physiological response.

A transcranial electrical stimulation device 1 having a wearing equipment 2 detachably worn onto a patient's head and at least a pair of electrodes 4 attached to the wearing equipment 2, the device for electrically stimulating a motor area of a patient's cerebral cortex by outputting current from the electrode 4 connected to a current generator. An engagement part 6 capable of engaging the wearing equipment 2 to a scalp with a thread-like body 8 is provided to the wearing equipment 2, and the electrode 4 is attached to the wearing equipment 2 protrudably to the head side of the electrode 4, and tip of the electrode 4 is capable of subcutaneously piercing through the head. It is unnecessary to bore a patient's skull outer layer with a drill, and a mounting of the electrode can be performed in a short time. The electrodes can be accurately positioned at predetermined positions of a patient's head, and the motor area of a cerebral cortex can be effectively stimulated.

A head-wearing wireless control transcranial electrical stimulation device includes a head-wearing part and a remote control part. An integrated circuit board is arranged within a cavity of a first end of the head-wearing part. The integrated circuit board controls a microcontroller. The microcontroller is connected with and controls a plurality of electrodes for contacting a human body through circuit modules. The microcontroller receives a control instruction from the remote control part through a Bluetooth communication terminal, and then controls the plurality of the electrodes to exert an alternating current or a direct current having preset density and frequency to a cerebral cortex. The microcontroller receives an electrode feedback signal, and sends the electrode feedback signal after being pre-processed to a display module of the remote control part to be displayed through the Bluetooth communication terminal.

A dual purpose sleep wearable headgear for both monitoring and stimulating the brain of a sleeping person is disclosed that provides a simple to use and safe platform for wearing consumer-type dual use brain stimulation and monitoring devices during sleep. The headgear enables a user to sleep comfortably while wearing the electronics and related electrodes needed for both EEG monitoring and transcranial electrical stimulation. The headgear can accept and support a miniaturized dual use monitoring / stimulation device on the forehead or the top of the head, where the bulk of the monitoring / stimulation device will not interfere with the user's sleeping position. The headgear disclosed takes the guesswork out of electrode placement, because the electrodes are prepositioned or are easily adjustable according to a predetermined pattern of electrode placement, and are appropriately sized so as to allow comfortable transcranial stimulation without producing skin irritation, and without awakening the user.

The invention provides a system and method for improving the sleep quality, and relates to the technical field of sleep monitoring. The method includes the following steps that a photoplethysmograph is used for acquiring a heart rate signal of a user and sending the heart rate signal to a control-system host machine; an actigraph is used for acquiring body motion information of the user and sending the body motion information to the control-system host machine; the control-system host machine obtains the sleep state of the user through analysis according to the heart rate signal and the body motion information and dynamically adjusts the stimulation mode and time of an transcranial electrical stimulation instrument according to the sleep state so as to improve the sleep quality of the user. According to the system and the method, the structure of sleep monitoring equipment is simplified, operation is simple, the cost is low, integrated assessment of the sleep quality and simulation improvement are achieved, and the sleep quality of the user can be effectively improved.

The invention provides a multi-parameter adjustable transcranial current stimulation system. The system comprises seven mutually connected parts: namely a main circuit, a conductive electrode, a micro-control unit, an AD module, a WIFI module, a display screen, and a mobile terminal application program. The main circuit comprises a power supply part, a voltage-regulating circuit and a frequency-modulating circuit, wherein the power supply part, the voltage-regulating circuit and the frequency-modulating circuit are connected with one another. According to the technical scheme of the invention, the stimulation system can realize the selection among three current stimulation modes, namely the tDCS mode, the tACS mode and the tRNS mode. In the tDCS current stimulation mode, the current amplitude can be adjusted within the range of 1mA-10mA. In the tACS current stimulation mode, the current amplitude can be adjusted within the range of 1mA-10Ma and the current frequency can be adjusted within the range of 1KHz-2KHz. In the tRNS current stimulation mode, the selection among different noise types, including low frequency, medium frequency, high frequency, white noise and the like, is realized. Meanwhile, users can monitor stimulation parameters and search the stimulation history according to needs by a mobile terminal.

Transcranial electrostimulation apparatus and method includes a first generator of bipolar pulses of a first predetermined frequency. A source of modulating control signals, producing an output at a second frequency less than the first predetermined frequency, is used to cause the output pulses from the first generator of pulses to vary in amplitude in a predetermined asymmetrical pattern at the frequency of the modulating control signals, with the asymmetrical pattern of signals applied to output electrodes designed to be attached to the scalp of a patient.

The invention belongs to the technical field of medical equipment, in particular to a non-invasive closed-loop transcranial electrostimulation device. The device of the invention comprises an electrode cap, a preamplifier, a host computer and an upper computer. The electrode cap is worn on the user's head and comprises a plurality of disc electrodes for collecting EEG signals and applying electrical stimulation. The preamplifier is connected with the electrode cap through a cable and comprises a plurality of selector switches and a plurality of amplifiers, which are used for switching the function of collecting and stimulating each electrode and preamplifying the EEG signal. The host computer is connected with the preamplifier through the cable, which is used for the acquisition, real-timeoperation, transmission of EEG signals and the generation of transcranial electrical stimulation signals. The host computer is wirelessly connected with the host computer, and is used for receiving the multi-channel EEG signals recorded by the host computer and displaying and recording the signals; or the signal real-time analysis algorithm and closed-loop control strategy are downloaded to the host. The invention can be used in the field of scientific experiment and rehabilitation treatment, and can utilize multi-channel EEG signal as feedback to carry out closed-loop electrical stimulation.

The invention relates to the brain-computer interface technology and medical treatment and rehabilitation instruments, and provides a neuromodulation method for improving the motor imagery ability in the brain-computer interface. By means of the method, the control efficiency of the MI-BCI can be effectively improved, the correctness of the MI-BCI can be improved, and considerable social benefits and economic benefits can be gained. According to the technical scheme of the transcranial electric stimulation device and method for improving the motor imagery ability in the brain-computer interface, before the MI-BCI is used, transcranial electric stimulation with a certain frequency is applied to the primary motor cortex of the human brain to adjust the ERD and ERS amplitude and distribution during motor imagery. The transcranial electric stimulation device and method are mainly applied to the occasions of designing and manufacturing of medical treatment and rehabilitation instruments adopting the brain-computer interface.

A headband for retaining electrodes in position on a patient's head is disclosed, having an adjustable frame, straps for holding electrodes against the head, each strap fastened to the headband by an adjustable support, and the supports having weights removably coupled thereto such that gravity pulls the headband down against the electrodes. The headband may be used for transcranial electrical stimulation treatment or other treatment by electrodes. Further disclosed is a method of retaining electrodes on a patient's head, having the steps of positioning a headband having straps on the head, tightening the headband and straps, inserting electrodes between the straps of the headband and the head, mounting weights to bias the headband downwardly, and loosening the straps for greater comfort. The headband and straps may have markings to facilitate placement according to an electrode marking system.

The invention provides a dyskinesia cortex plasticity management method based on transcranial electrical stimulation brain-muscle coupling. The method comprises the following steps: firstly, a functional brain area multi-lead EEG signal is analyzed; a brain function network modeling method is adopted to calculate brain function network indexes of connectivity and small-world characteristics, the brain function network characteristics before and after tDCS stimulation are compared, and functional connection and nerve remodeling rules of a functional anterior region, a functional region and a functional perception region of a stimulated hemisphere in the exercise activity period are revealed; then, brain-brain, brain-muscle and muscle-muscle coupling characteristic indexes are extracted by adopting a multi-level neuromuscular coupling analysis method based on causal measurement of a dynamic regression model, and the rehabilitation effect of upper limb movement functions is described fromdifferent side surfaces; and finally, the correlation between the brain-muscle electric coupling characteristics and the influence rule of the tDCS on the nerve plasticity is studied, a basis is provided for further improvement of the stimulation mode and parameters of the tDCS, and effective guidance and management of motor function cortex nerve remodeling are achieved.

The invention provides a transcranial electrical stimulation therapeutic instrument based on adjustable parameter, the instrument comprises a micro-control unit (4), a user operating unit, a simulating electrode (3) and a current control circuit (6); the user operating unit transmits an operating signal of a user to the micro-control unit (4) to perform digital-to-analogue conversion processing, the micro-control unit (4) transmits a voltage signal corresponding to simulating waveform to the current control circuit (9), and the current control circuit (9) changes the simulating waveform and current intensity of the simulating electrode (3). According to the invention, the instrument is small in size and has good portability; the instrument has a good user operating button system and has advantages of quick response and good stability, the instrument also comprises a liquid crystal display which can display parametric variation in real time, so that the user has good human-computer interaction experience, the output of positive and negative waveforms can be realized, and the instrument can be made to be suitable for different users. In addition, the instrument also comprises a multi-level security detection system, so that the instrument can protect the users to the greatest extent.

The invention discloses a multi-channel transcranial electrical stimulation device and a method adopted by the multi-channel transcranial electrical stimulation device. The multi-channel transcranialelectrical stimulation device comprises an upper computer module, an ARM control module, an FPGA waveform generating module and an analogue circuit module, wherein the ARM control module is mainly responsible for control data sent by the upper computer module, and transmits the control data to an RAM storage unit of the FPGA waveform generating module through a flexible static memory controller; the FPGA waveform generating module comprises a plurality of channels which are independent from each other, each channel is provided with a waveform generating module, each channel can independently generate waveform, and the control data obtained by the RAM storage unit can control the generation of the waveform of each channel; the parameters of each single channel can be adjusted under the multi-channel transcranial electrical stimulation, the current feedback is increased, and the stimulation current is stable.

The present invention relates to an electrotherapy stimulation device having at least three fully programmable multipurpose electrodes in fixed positions and the use of such device for achieving various cognitive effects such as those involved in creative problem solving. The electrodes of the present invention are multipurpose electrodes designed so each electrode can selectively serve multiple functions such as, but not limited to, as anode, cathode or ground of a stimulation circuit.

A dual purpose sleep wearable headgear for both monitoring and stimulating the brain of a sleeping person is disclosed that provides a simple to use and safe platform for wearing consumer-type dual use brain stimulation and monitoring devices during sleep. The headgear enables a user to sleep comfortably while wearing the electronics and related electrodes needed for both EEG monitoring and transcranial electrical stimulation. The headgear can accept and support a miniaturized dual use monitoring / stimulation device on the forehead or the top of the head, where the bulk of the monitoring / stimulation device will not interfere with the user's sleeping position. The headgear disclosed takes the guesswork out of electrode placement, because the electrodes are prepositioned or are easily adjustable according to a predetermined pattern of electrode placement, and are appropriately sized so as to allow comfortable transcranial stimulation without producing skin irritation, and without awakening the user.

The invention discloses an electrical stimulation device integrating transcranial electrical stimulation and vagus nerve stimulation. The electrical stimulation device is composed of a transcranial electrical stimulation module and a vagus nerve electrical stimulation module. The transcranial electrical stimulation module is composed of an ARM control unit, an FPGA waveform generation unit and ananalog circuit. The ARM control unit sends control command waveform parameter information to the FPGA through the FSMC; the FPGA waveform generation unit generates a four-channel digital waveform signal. Firstly, the four-channel digital waveform signal is converted into a four-channel analog signal waveform through a digital-to-analog conversion circuit, then the four-channel analog signal waveform is amplified through a primary amplification circuit, interference signals except waveform signals are filtered out through a filter circuit, and then the waveform is amplified to the waveform amplitude required by the control unit through a secondary amplification circuit to be output. The electrical stimulation device is quite high in safety, the current value, waveform parameters and the like need to be adjusted in real time, the human body safety is guaranteed to be not damaged, and meanwhile, the module can output constant-current stimulation and can output different kinds of waveformsin a transcranial alternating-current stimulation mode.

The present invention relates to a transcranial electrical stimulation (TES) system in that several sets of manipulated, pre-stored raw data are executed. TES signals are generated and output to user in terms of sessions. The output waveform in each singular session is a composite type and is designed mainly by means of Fourier Transform basis together with numerical analysis and mathematical curves fitting techniques. Hence, the electrical signals' frequencies, amplitudes and phase angles are varying during the time of application within just ONE singular session by one device. The kinds of variations in parameters such as frequencies, amplitudes and phase angles are tailor-made to the needs of improvement required in several brain disorders caused or related neurological disorders symptoms. With the help of the wearing design, the brain can be stimulated in dedicated positions such that the TES signals are continuously monitored by the unit.

The invention discloses an electric stimulator through skull and its method, including the first generator which generates bipolar impulses of the first preset frequency, the modulation control signal source which generates the second output frequency lower than the first preset frequency and enables the output impulses of the first impulse generator to change amplitudes over the preset asymmetry graphs of the modulation control signals' frequency, and the designed output polar in order to make the signals' asymmetry graph apply to the attached patient' scalp.

Systems, apparatuses, and methods for providing non-transcranial electrical stimuli to a biological subject may employ a support structure, at least one waveform generator, and at least a first electrode and a second electrode. The system can be sized and dimensioned to be worn on a head of the biological subject and operable to deliver non-transcranial electrical stimuli to at least one of the temporomandibular joints of the biological subject.

The invention relates to a programmable flexible transcranial electrical stimulation and electroencephalogram acquisition integrated system. The programmable flexible transcranial electrical stimulation and electroencephalogram acquisition integrated system comprises a 64-channel bidirectional electrode array, an acquisition and stimulation unit and a man-machine interaction terminal, wherein 64 bidirectional electrodes of the 64-channel bidirectional electrode array are respectively distributed in different areas of scalp and used for acquiring electrophysiological signals from the scalp or applying electrical stimulation to the scalp; the acquisition and stimulation unit is connected with the 64-channel bidirectional electrode array to control the acquisition and stimulation state of each bidirectional electrode; on the one hand, the acquisition and stimulation unit acquires electroencephalogram signals on the scalp through the bidirectional electrodes in the acquisition state; on the other hand, the acquisition and stimulation unit outputs stimulation current to the scalp through the bidirectional electrodes in the stimulation state; and the man-machine interaction terminal is used for acquiring stimulation states and stimulation parameters through the set electrodes and storing and displaying electroencephalogram signal data.

A transcranial electrical stimulation device 1 having a wearing equipment 2 detachably worn onto a patient's head and at least a pair of electrodes 4 attached to the wearing equipment 2, the device for electrically stimulating a motor area of a patient's cerebral cortex by outputting current from the electrode 4 connected to a current generator. An engagement part 6 capable of engaging the wearing equipment 2 to a scalp with a thread-like body 8 is provided to the wearing equipment 2, and the electrode 4 is attached to the wearing equipment 2 protrudably to the head side of the electrode 4, and tip of the electrode 4 is capable of subcutaneously piercing through the head. It is unnecessary to bore a patient's skull outer layer with a drill, and a mounting of the electrode can be performed in a short time. The electrodes can be accurately positioned at predetermined positions of a patient's head, and the motor area of a cerebral cortex can be effectively stimulated.

The invention relates to a transcranial electrical stimulation control method, a control device, a transcranial electrical stimulation device and a system. The transcranial electrical stimulation control method comprises the steps of acquiring a real-time electroencephalogram signal of a user acquired by an input electrode; determining a current sleep stage of the user according to the real-time electroencephalogram signal, wherein the sleep stage comprises an N1 stage, an N2 stage, an N3 stage, an N4 stage and an REM stage; judging whether the current sleep quality of the user is good or not according to the real-time electroencephalogram signal under the condition that the current sleep stage of the user is determined to be the N2 stage, the N3 stage or the N4 stage; and controlling an output electrode to output an electrical stimulation signal matched with the current sleep stage and the sleep period of the user under the condition that the current sleep quality of the user is determined to be poor. According to the invention, a problem brought about by the fact that only fixed slow-wave electrical stimulation can be applied to the user in the prior art is solved.

The invention discloses a transcranial electrical stimulating assembly, device and system and an application, and relates to the technical field of experiment equipment. The transcranial electrical stimulating assembly, device and system are used for performing animal skull electrical stimulation. The skull electrical stimulating assembly comprises a headband, a glass sheet, a wire and a conducting adhesive tape, wherein an imaging hole is formed in the headband; the glass sheet is used for being in contact with the cortex of the animal; the wire is used for surrounding the periphery of the glass sheet and is in contact with the skull of the animal; and the conducting adhesive tape is adhered to and covers the wire and the skull. Through the adoption of the transcranial electrical stimulating assembly, device and system and the application disclosed by the invention, long-term transcranial electrical stimulation of animals can be realized; and the transcranial electrical stimulating assembly can be used for researching the changes of cellular morphology and functions in the long-term electricity stimulating process of the animals under a sober state, and the plasticity mechanism generated by electrical stimulating can be further researched.

The invention relates to a system and method for improving auditory steady-state response brain-computer interface performance. The system comprising a brain-Computer interface system and transcranialelectrical stimulation system; the brain-computer interface system comprises a computer, an auditory stimulator and an EEG signal acquisition module, Computers and Auditory Stimulators, EEG signal acquisition module is connected, the subjects received the stimulation sound from the auditory stimulator through the air-conductive headphones attached to both ears, EEG signal acquisition module is connected with that cerebral cortex of the subjects through EEG cap electrode. The auditory stimulator generates three different frequencies of stimulation, which are applied to the subjects through theair-conduction earphones. The transcranial electrical stimulation system applies specific electrical current to the target area of the subjects. The EEG signal acquisition module collects EEG signalsthrough the EEG cap electrode and transmits them to the computer for processing. The invention combines the transcranial electrical stimulation system into the brain-computer interface system, and improves the auditory steady-state response signal-to-noise ratio of the auditory steady-state response in the brain-computer interface, which brings convenience to practical applications.

The invention provides a high-accuracy transcranial electrostimulation device. The transcranial electrostimulation device comprises a stimulation control unit, a channel preexamination unit and an output electrode target-shaped focusing unit; the stimulation control unit comprises a first man-machine interaction terminal, a first microprocessor, a first constant-current power supply and a current output terminal which are electrically connected sequentially; an output current detection module and a contact quality detection module are further connected between the first microprocessor and the current output terminal; the channel preexamination unit comprises a second man-machine interaction terminal, a second microprocessor, a second constant-current power supply, a channel switching module and a load interface which are electrically connected sequentially; a channel quality detection module is further connected between the channel switching module and the second microprocessor; the first microprocessor is electrically connected with the second microprocessor, and the current output terminal is electrically connected with the channel switching module; and the load interface is further electrically connected to the output electrode target-shaped focusing unit. The transcranial electrostimulation device has the advantages of achieving pre-scanning, guaranteeing contact quality and improving spatial focusing of transcranial electrostimulation.