The invention discloses an intelligent engineering operation and maintenance supervision method. The method comprises an infrastructure layer, an information resource layer, an application support layer, an application layer and a user layer. The infrastructure layer is used for providing a network, hardware and server environment, securing platform operation. The information resource layer provides basic information data and service data, and uploads the data to an application support layer. The application support layer aggregates dispersed and heterogeneous applications and information resources. Through unified access entry, basic services are provided for an application layer. The application layer provides a software operation entrance for the user layer, the user layer provides a system visual operation interface for a user, and the application layer comprises a project management system, a construction management system, an inspection management system, an operation and maintenance management system, a knowledge base management system, an asset management system, a statistical report system, a process management system, a system management system and a WeChat applet. The engineering project is integrally supervised, so that the operation and maintenance management cost is reduced, and the working efficiency is improved.