34 results about "Memory consolidation" patented technology

Devices, systems and methods to modify memory and / or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. Described herein are systems, methods and devices to enhance a user's cognitive function in memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. The machine may record ambient sensory inputs during awake acquisition or reinforcement / relearning and replay all or an extracted form of the ambient sensory stimuli during a specified portion of the user's sleep. A stimulus may be delivered to a user to affect brain activity during sleep to modulate the phase of a user's sleep, quality of sleep, and / or quality or intensity of brain rhythms during a particular phase of sleep.

Devices, systems and methods to modify memory and / or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. For example, described herein are systems, methods and devices to enhance a user's cognitive function in such areas as memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. In some variations the machine records ambient sensory inputs during awake acquisition or reinforcement / relearning and replays all or an extracted form of the ambient sensory stimuli a specified portion of the user's sleep.

Devices, systems and methods to modify memory and / or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. For example, described herein are systems, methods and devices to enhance a user's cognitive function in such areas as memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. In some variations the machine records ambient sensory inputs during awake acquisition or reinforcement / relearning and replays all or an extracted form of the ambient sensory stimuli a specified portion of the user's sleep.

Devices, systems and methods to modify memory and / or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. For example, described herein are systems, methods and devices to enhance a user's cognitive function in such areas as memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. In some variations the machine records ambient sensory inputs during awake acquisition or reinforcement / relearning and replays all or an extracted form of the ambient sensory stimuli a specified portion of the user's sleep.

Impairments in memory consolidation are treated with an amphetamine compound. In one embodiment, the method includes administering an l-amphetamine compound. In another embodiment, the method includes administering an l-methamphetamine compound. The method can include determining memory consolidation before, during and / or after administering the amphetamine compound.

The invention relates to a graphics processing unit based matrix transpose optimization method. The method includes: converting an R-line S-column input matrix into a one-dimensional array, allocating storage spaces and copying data; setting a two-dimensional index space; computing global identifiers, workgroup identifiers and local identifies of work items; partitioning the matrix, and corresponding matrix partitions to workgroups; applying for local memories in the workgroups, copying the data into the local memories and synchronously waiting for completion of data copying; computing column and line indexes of the transposed data in a global memory; computing locations of output data in the global memory and local memories; assigning the data of the local memories to the one-dimensional array in the global memory to realize conflict-free memory consolidation access; and copying the one-dimensional array to the memories to form an S-line R-column superposed matrix. By the method, parallel computation of consolidation access and matrix transpose is realized, and execution efficiency of programs is improved.

The invention provides a learning scene processing method and device, and the method comprises the steps: displaying a learning scene interface which comprises a plurality of virtual objects, and enabling the position relationship and size of the virtual objects in the learning scene interface to simulate the layout of a real scene; receiving a selection operation on the learning scene interface,determining a virtual object selected by the selection operation in the learning scene interface, and determining the virtual object as a target object; and obtaining learning resources of the targetobject, and displaying a learning interface corresponding to the learning resources. Due to the fact that the learning scene simulates the layout of a real scene, the combination of learning and the scene is achieved, the association between learning and the scene is enhanced, learning gamification and memory consolidation can be achieved at the same time, learning interest is stimulated, and thelearning effect is improved. Especially for learning of English words of children, real scenes, gamification learning and teaching through lively activities, the learning effect of the English words can be improved for the children.

A medicament for promoting memory consolidation, which comprises, as an active ingredient, a non-natural retinoid, preferably a retinoid having a basic skeleton comprising an aromatic ring bound with an aromatic carboxylic acid or tropolone by means of a bridging group, more preferably 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthaleny)carbamoyl]benzoic acid or 4- [(3,5-bis-trimethylsilylphenyl)-carboxamido]benzoic acid.

The invention discloses a method for training a risk decision behavior of a rat. The method comprises the following steps of training device preparation, experimental animal preparation, scene adaptation training, preference detection and correction training, assignment training, memory consolidation training and risk decision training. The training method and step design are more reasonable and scientific, the training time can be remarkably shortened, the training efficiency can be improved, the training success rate can be higher, real and reliable experimental data can be obtained, and the method is conductive to efficient monitoring conducted by researchers on animal behaviors.

Devices, systems and methods to modify memory and / or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. For example, described herein are systems, methods and devices to enhance a user's cognitive function in such areas as memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. In some variations the machine records ambient sensory inputs during awake acquisition or reinforcement / relearning and replays all or an extracted form of the ambient sensory stimuli a specified portion of the user's sleep.

The invention discloses a method and a terminal for assisting users in new word consolidation before and after reading. The method for assisting users in new word consolidation before and after reading includes that the terminal receives input signals for starting text reading or stopping text reading, acquires new word storage information from a new word storage database of a local memory, determines whether starting a new word consolidation function according to the new word storage information, starts the new word consolidation function and provides a new word learning interface when needing to start the new word consolidation function, wherein the new word storage information comprises new words to be consolidated; the terminal acquires corresponding new word learning data from a new word learning database and displays on a new word learning interface. A user can select to learn and consolidate the new words inquired when reading before and after reading so as to assist the user in deepening the memory and improve the word recognition and learning efficiency of the user.

Described is a system to accelerate memory consolidation using a steerable transcranial intervention. During operation, the system generates a unique transcranial and steerable stimulation tag to associate with memory of a task or event. Once the tag is generated, the system activates a plurality of electrodes (e.g., as few as four) to apply the unique transcranial stimulation tag during the occurrence of the event or task to be consolidated.

The present invention makes available methods and reagents for enhancing and / or restoring long-term memory function and performance.

Described is a system for decoding and validating memory consolidation. During operation, the system receives electroencephalographic (EEG) data while a subject is performing a specific task. Nuisance signals are then removed from the EEG data, resulting in a nuisance free signal. Skill feature vectors are generated from the nuisance free signal using time-invariant feature extraction. A skill classifier can then be trained for the specific task based on the skill feature vectors to generate a subject specific model regarding a memory replay for the specific task. Finally, electrodes in a neural cap are activated based on the memory replay.

Methods of identifying gene targets associated with learning and memory and with memory consolidation, as well as to specific nucleic acid molecules that have been discovered to be associated with memory consolidation are provided. Accordingly, the invention also relates to methods of modulating learning and memory function, methods of diagnosing learning and memory disorders, and methods of identifying compounds that modulate learning and memory function via manipulations of the nucleic acid molecules and their products.

Impairments in memory consolidation are treated with an amphetamine compound. In one embodiment, the method includes administering an l-amphetamine compound. In another embodiment, the method includes administering an l-methamphetamine compound. The method can include determining memory consolidation before, during and / or after administering the amphetamine compound.

Described is a system to accelerate memory consolidation using a steerable transcranial intervention. During operation, the system generates a unique transcranial and steerable stimulation tag to associate with memory of a task or event. Once the tag is generated, the system activates a plurality of electrodes (e.g., as few as four) to apply the unique transcranial stimulation tag during the occurrence of the event or task to be consolidated.

The invention discloses a pharmaceutical composition for enhancing cognition, preventing and / or treating cognition disorders, including 50-100 mg / kg ferulic acid or a pharmaceutically acceptable salt or derivative thereof, and a pharmaceutically acceptable carrier or excipient. The pharmaceutical composition is useful in the treatment of disorders of learning acquisition, memory consolidation, and retrieval.

The invention discloses treatment effect of a compound medicine on alzheimer's disease. The compound medicine is composed of galanthamine and meclofenoxate in a combination and matching dosage proportion of (0.5-4):(17.5-70), preferable 2:35. Under the matching condition, galanthamine and meclofenoxate are combined to achieve obvious improving effect for memory acquisition disorder, memory consolidation disorder and memory representation disorder. Meanwhile, the compound medicine can achieve effects of preventing and treating the alzheimer's disease by delaying brain ageing, reducing amyloid deposition in brain, protecting cholinergic neuron and the like. Moreover, learning memory can be improved and the alzheimer's disease can be prevented and treated by combined use of galanthamine and meclofenoxate.

The invention discloses a pink noise generator for brain memory consolidation stimulation equipment. The pink noise generator is composed of a main control module, a power module, a storage module, anaudio module, a display module, a rotary coding switch module and an output module; the power module, the audio module, the display module and the rotary coding switch module are in unilateral connection with the main control module; the storage module is in bidirectional connection with the main control module; and the audio module is in unilateral connection with the output module. The pink noise generator of the invention can generate pink noise that best matches pink noise parameters. The generator has a simple structure, stable performance and powerful functions, and is especially suitable for brain memory consolidation stimulation equipment.

Described is a closed-loop intervention control system for memory consolidation in a subject. During operation, the system simulates memory changes of a first memory in a subject during waking encoding of the memory, and then while the subject is sleeping and coupled to an intervention system. Based on the simulated memory changes, the system predicts behavioral performance for the first memory, the behavioral performance being a probability that the first memory can be recalled on cue. The system can be used to control operation (e.g., turn on or off) of the intervention system with respect to the first memory based on the behavioral performance of the first memory determined by the simulation.

The invention discloses a method for constructing incremental LSTM by utilizing training process compression and memory consolidation. According to the method, an important input moment in the training process is selected by utilizing the activity of the LSTM gate unit, the training process is compressed to form historical memory, the compressed memory is effectively fused with training on new data, and the network memory is consolidated by utilizing historical information so as to meet the incremental processing requirement on the sequence data. According to the method, the problems of high storage overhead and low training efficiency of an existing LSTM system can be avoided, the training efficiency of the LSTM for dynamically increased sequence data is improved, forgetting of historicalinformation is avoided, and the effectiveness and practicability of the LSTM are guaranteed.

The invention discloses a soft capsule with a function of auxiliary improvement of memory. The soft capsule is prepared from a capsule shell and a content filled in the capsule shell, wherein the content is prepared from the following raw materials in parts by weight: 170-270 parts of micro-alga oil and 170-270 parts of fish oil. The invention also discloses a preparation method of the soft capsule with a function of auxiliary improvement of memory. The soft capsule disclosed by the invention is capable of effectively providing DHA for organisms, effectively promoting memory acquisition, memory consolidation and memory reproduction, enhancing the memory quotient of a user taking the soft capsule, and achieving the purpose of auxiliary improvement of memory. The soft capsule prepared by themethod disclosed by the invention has the characteristic of good stability.

The present invention relates to a composition that comprises the peptide QBP1 for use in the inhibition of memory consolidation, after a trauma, more preferably in Post-Traumatic Stress Disorder or related diseases.

The present invention relates to closed-loop intervention control systems and methods for memory consolidation in subjects. A closed-loop intervention control system for memory consolidation in subjects is described. During operation, the system simulates a memory change of the subject's first memory during awake encoding of the first memory and then while the subject is asleep and coupled to the intervention system. Based on the simulated memory changes, the system predicts a behavior of the first memory, the behavior being a probability that the first memory can be recalled by a cue. The system may be configured to control operation (eg, turn on or off) of an intervention system for the first memory based on the behavioral performance of the first memory determined by the simulation.

Described is a closed-loop control system for memory consolidation in a subject. During operation, the system encodes information regarding environmental items as memories in both a long-term memory store and a short-term memory store. The system generates an activation level representation of a memory of interest related to at least one of the environmental items. An association strength representation for the memories is also generated. Memory consolidation is simulated when the subject is in NREM sleep or quiet waking by strengthening the association strength representation related to the memory of interest. The system predicts behavioral performance for the memory of interest as a probability that the memory of interest can be recalled on cue. When the behavioral performance is below a threshold, an intervention system can be activated.

The invention relates to a traditional Chinese medicine preparation for enhancing and consolidating memory. It is made of traditional Chinese medicine raw materials, and the weight ratio of the medicine is as follows: ginseng: 2-8, cypress kernel: 4-10, Shichangpu: 4-8, gorgon : 8-16, Ginkgo biloba: 4-10, Pueraria: 4-12, Paeoniae Alba: 6-10, Ganoderma lucidum: 5-10, Poria: 6-18, Polygala: 4-8, Chinese yam: 10-20. The beneficial effect of the invention is that the clinical test has obvious effect on enhancing and consolidating memory, has no toxic and side effects, has sufficient raw materials, and is simple to make.