The invention provides an ECG (electrocardiograph) feature extraction method integrating Butterworth filtering and wavelet transformation, and belongs to the technical field of medical computers. A core concept is described as follows: performing de-noising processing on power frequency interference of an original ECG signal; meanwhile, removing baseline drift in a curve fitting manner; respectively positioning a wave Q, a wave R and a wave S with a differential threshold method and a wavelet transformation method after a relatively accurate ECG signal is acquired, comparing the waves Q, R andS with information marked by an expert, and respectively regulating threshold, scale and translation amount parameters to obtain an optimal positioning result. Based on the result, the wave Q, the wave R and the wave S are positioned respectively by adopting the differential threshold method or the wavelet transformation method. According to the extraction method provided by the invention, the more accurate de-noising processing can be performed on the original ECG signal; in addition, the waves Q, R and S can be positioned accurately, therefore, a foundation is laid for a digital analysis onan ECG.