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Saussurea involucrata drop pill and its preparation method

A technology of snow lotus and dripping pills, applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as being unfavorable for improving the ability of patients to seek medical treatment, harming the health of staff, and adversely affecting the overall health level, etc. The effect of bioavailability, convenient storage, convenient production

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] Now with several groups of specific examples, the preparation method of Saussurea oleifera dripping pills of the present invention will be further described.

[0041] Group 1: Tests with a single matrix

[0042] 1. According to the section [Preparation method of a kind of medicinal extract], the extract dry powder containing the active ingredient of Snow Lotus of Tianshan Mountains is prepared for later use;

[0043] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0044] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0045] 4. Then prepare according to the [preparation method], that is, various snow lotus dripping pills with different specifications can be prepared.

[0046] [test results]

[0047] Experiment 1: In ...

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Abstract

The invention relates to a medicinal oral preparation, i.e., a saussurea involucrata drop pill for treating rheumatic arthritis, chronic infectious arthritis and dysmenorrheal, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administration, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

Description

technical field [0001] The present invention relates to a medicine that has the functions of warming kidney and supporting yang, expelling wind and dampness, promoting blood circulation and dredging menstruation, and is used for treating rheumatoid arthritis, rheumatoid arthritis and dysmenorrhea caused by deficiency of kidney yang, cold-damp stasis and other diseases. The pharmaceutical composition particularly relates to an oral drop pill preparation of a pharmaceutical composition reformed from a dosage form based on Saussurea chinensis oral liquid. Background technique [0002] Snow lotus oral liquid prepared according to the formula and extraction process given in the national drug standard WS-10155 (ZD-0155)-2002 is a kind of medicine that has the functions of warming the kidney and supporting yang, expelling wind and dampness, promoting blood circulation and dredging menstruation. It is a traditional Chinese medicine preparation for the treatment of rheumatoid arthrit...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P15/00A61P29/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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