Cefadroxil oral disintegrant tablet, and its prepn. method

Abstract

An oral disintegrating tablet of dracefal contains dracefal and the medicinal excipient (water-soluble filler, disintegrant, lubricant, wetting agent, or adhesive). Its preparing process is also disclosed. Its advantages are high disintegrating speed, quickly taking its effect, less residue and low by-effect.

Description

technical field [0001] The invention relates to a cefadroxil orally disintegrating tablet and a preparation method thereof. technical background [0002] Cefadroxil is a broad-spectrum antibiotic with high antibacterial activity against Staphylococcus aureus, various streptococci and anaerobic cocci. It also has a strong antibacterial effect on certain Enterobacteriaceae. Its bactericidal mechanism is similar to other β-lactam antibiotics, and it is achieved by inhibiting the formation of bacterial cell walls. The drug has the advantages of broad antibacterial spectrum, strong bactericidal effect, long half-life and the like. It is clinically used for respiratory tract, urinary tract, skin, and soft tissue infections caused by sensitive bacteria. Its adverse reactions are few and mild, mainly gastrointestinal reactions. [0003] The structural formula of cefadroxil is as follows: [0004] [0005] The dosage forms of cefadroxil currently in clinical use include table...

AI Technical Summary

Problems solved by technology

[0005] The dosage forms of cefadroxil currently in clinical use include tablets, capsules, and granules. These oral dosage forms need to be taken with water, and it will be difficult for patients who have difficulty swallowing or inconvenient water intake; although granules are specially designed for children. However, since most children cannot drink it by themselves, and it is inconvenient to take granules in schools or kindergartens, these dosage forms cannot fully meet the medication needs of all patients

Images