Application of tartary buckwheat flavone in preparation of medicines or health-care products for inhibiting bacteria or preventing and treating gastritis

Abstract

The invention belongs to the technical field of medicines and foods, and particularly relates to application of tartary buckwheat flavone in preparation of medicines or health-care products for inhibiting bacteria or preventing and treating gastritis. The technical problem to be solved by the invention is to provide application of tartary buckwheat flavone in preparation of medicines or health-care products for inhibiting bacteria or preventing and treating gastritis. Test results show that the tartary buckwheat flavone not only can inhibit the growth of helicobacter pylori, but also can inhibit the expression of helicobacter pylori virulence genes; in addition, the tartary buckwheat flavone can also be used for treating and preventing expression of inflammatory factors caused by infection of gastric mucosa epithelial cells by helicobacter pylori; and main components of the tartary buckwheat flavone, namely rutin, nicotiflorin, quercetin and kaempferol, can also effectively inhibit helicobacter pylori and inflammation caused by infection of the helicobacter pylori. The application of the tartary buckwheat flavone in preparing medicines or health-care products for inhibiting bacteria or preventing and treating gastritis provides a new choice for life cultivation, health preservation and clinical medication.

Description

Technical field [0001] The present invention belongs to the technical field of food and medicine, particularly to the use of flavonoids in the manufacture of buckwheat bacteriostatic or prevention of gastritis medicament or health-care product. Background technique [0002] Buckwheat (Fagopyrum tataricum (L.) Gaertn) is a country in the Yunnan-Guizhou Plateau and the Loess Plateau widely grown crop, is Polygonaceae (Polygonaceae) Buckwheat belongs to (Fagopyrum Mill) that can both eat drink dicots also pharmaceutically acceptable careen grains. Buckwheat contains many nutrients and pharmacologically active ingredients, in addition to outside as a food crop, buckwheat flavonoids have been shown to have antioxidant, free radical clearance, lower blood sugar, blood lipids, blood pressure, cholesterol, and prevention of atherosclerosis and other effects . Buckwheat flavonoids is the main active ingredient, flavonoids study also shows that it has a role to prevent and treat a variety ...

AI Technical Summary

Problems solved by technology

Due to the widespread use of antibiotics, the drug resistance of H.pylori is increasing, and the action of antibiotics leads to gastrointestinal flora imbalance and dysfunction. The treatment process is often accompanied by a variety of adverse reactions, and the curative effect often fails to achieve the expected effect

[0004] Many studies have found that, compared with pure western medicine treatment, integrated traditional Chinese and western medicine has better curative effect and higher clinical application value in the treatment of inflammation caused by H. pylori; some studies even found that simple traditional Chinese medicine can also eradicate H. pylori. In addition, most of the related research on tartary buckwheat flavonoids is the application of lowering blood fat and blood sugar, and the research and development of health wine preparation technology. At present, no tartary buckwheat flavonoids have been found in the traditional Chinese medicine composition used to treat H. pylori. There is no report on inhibiting H.pylori and its inflammation caused by H.pylori infection by combining tartary buckwheat flavonoid extracts rutin, nicotinic acid, quercetin, kaempferol, etc.

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