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Lipoic acid soft capsule for treating diabetes and complications thereof as well as preparation method and application of lipoic acid soft capsule

A lipoic acid and diabetes technology, applied in the field of medicine, can solve the problems of difficulty in taking medicine, physical damage of patients, inconvenience of taking medicine in real time, etc., and achieve the effect of accelerating nerve conduction speed, taking convenience and reducing difficulty of taking medicine

Pending Publication Date: 2022-02-11
锦州福寿堂医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the current treatment for diabetes is generally controlled by surgical treatment or long-term drugs. The surgical treatment is not only costly, but also has certain risks and is easy to cause damage to the patient's body. Therefore, most patients choose to use drugs for treatment. Lipoic acid is generally used as the main raw material in drug treatment, but now the drug dosage forms of lipoic acid are mainly injections, tablets and hard capsules. Poor environmental conditions can easily lead to infection, while tablets and hard capsules are not conducive to taking by patients, and it is more difficult for patients who have difficulty swallowing

Method used

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  • Lipoic acid soft capsule for treating diabetes and complications thereof as well as preparation method and application of lipoic acid soft capsule
  • Lipoic acid soft capsule for treating diabetes and complications thereof as well as preparation method and application of lipoic acid soft capsule

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preparation example Construction

[0022] In addition, the embodiment of the present application also provides a preparation method of lipoic acid soft capsules for treating diabetes and its complications, comprising the following steps: mixing lipoic acid, fatty acid glycerides and vegetable oil, heating and stirring to obtain the mixture for later use, The auxiliary materials are heated and then lowered in temperature and then mixed to obtain a rubber material, which is vacuumized and then filtered to obtain a glue solution, and the glue solution is mixed with the mixture to obtain lipoic acid soft capsules for treating diabetes and its complications. In this method, the main ingredients are firstly mixed completely, and heated and stirred, so that lipoic acid and fatty acid glycerides are fully dissolved in the vegetable oil, thereby ensuring that lipoic acid and fatty acid glycerides can be fully combined under the action of the vegetable oil medium, so that the subsequent lipoic acid can It is better carrie...

Embodiment 1

[0029] This embodiment provides a lipoic acid soft capsule for the treatment of diabetes and its complications, comprising the following raw materials: α-lipoic acid 35g, fatty acid glycerides 20g, soybean oil 45g, beeswax 4.36g, glycerin 10.74g, sorbitol 1.64g, 0.82g of titanium dioxide, 0.82g of iron oxide, 30.94g of water and 28.21g of gelatin.

[0030] This embodiment also provides a preparation method of lipoic acid soft capsules for treating diabetes and its complications, comprising the following steps: mixing lipoic acid, fatty acid glycerides and vegetable oil, heating and stirring at 55°C and 40r / min, The mixture is obtained for later use, the auxiliary materials are heated to 90°C and then cooled to 25°C with a gradient of 10°C, and then mixed to obtain a rubber material, which is vacuumized and filtered through a 60-mesh screen to obtain a glue solution, which is mixed with The mixture is mixed evenly to obtain lipoic acid soft capsules for treating diabetes and it...

Embodiment 2

[0032] This embodiment provides a lipoic acid soft capsule for the treatment of diabetes and its complications, comprising the following raw materials, α-lipoic acid 50g, fatty acid glycerides 5g, soybean oil, sunflower oil, corn oil, peanut oil, pumpkin seeds Oil, rapeseed oil, cottonseed oil and rice bran oil total 45g, beeswax 6.3g, glycerin 11.2g, sorbitol 1.64g, titanium dioxide 0.82g, iron oxide 0.82g, water 30.94g and gelatin 28.21g.

[0033] This embodiment also provides a preparation method of lipoic acid soft capsules for treating diabetes and its complications, comprising the following steps: mixing lipoic acid, fatty acid glycerides and vegetable oil and then heating and stirring at 65°C and 50r / min, The obtained mixture is ready for use, the auxiliary materials are heated to 100°C and then cooled to 35°C with a gradient of 10°C, and then mixed to obtain the rubber material, which is vacuumized and filtered through a 100-mesh screen to obtain the glue solution, whic...

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Abstract

The invention provides a lipoic acid soft capsule for treating diabetes and complications thereof as well as a preparation method and application of the lipoic acid soft capsule, and relates to the technical field of medicines. The lipoic acid soft capsule for treating diabetes and complications thereof comprises main materials, the main materials comprise the following raw materials: 35-50wt% of lipoic acid, 5-20wt% of fatty glyceride and 30-45wt% of vegetable oil, and the lipoic acid comprises alpha-lipoic acid; the lipoic acid soft capsule not only can effectively and radically treat diabetes mellitus, but also has the advantages of quicker effect, convenience in taking and no taking burden on the body, and can also treat various complications and the like caused by diabetes mellitus. In addition, the invention also provides a preparation method of the composition for treating diabetes and complications thereof, according to the preparation method, the composition can be prepared through simple mixing, the operation difficulty is low, the technological process is simple, the difficulty of operators is reduced, and large-scale and large-scale production of the composition is facilitated.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a lipoic acid soft capsule for treating diabetes and its complications, a preparation method and application thereof. Background technique [0002] Diabetes mellitus (Latin: diabetes mellitus, abbreviated as DM, referred to as diabetes) is a metabolic disease, which is characterized by the patient's blood sugar higher than the standard value for a long time. High blood sugar can cause symptoms commonly known as "three excesses and one deficiency": eating more, drinking more, frequent urination and weight loss. With type 1 diabetes, symptoms appear over a period of a week to a month, and with type 2 diabetes later. Regardless of the type of diabetes, many complications can arise if left untreated. Common symptoms include blurred vision, headache, muscle weakness, slow wound healing and very itchy skin. Acute complications include diabetic ketoacidemia and hyperosmolar hypergly...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K31/385A61K47/42A61K47/44A61K47/14A61K47/02A61K47/10A61K47/26A61P3/10A61P9/00A61P9/14A61P13/12A61P25/02
CPCA61K9/4858A61K9/4825A61K9/4816A61K31/385A61P3/10A61P13/12A61P9/14A61P9/00A61P25/02
Inventor 于喜洋
Owner 锦州福寿堂医药科技有限公司
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