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Method for topical protection against atmospheric pollutant molecules and/or free radicals produced by exposure to ultraviolet radiation

A technology for air pollutants and local protection, applied in pharmaceutical formulations, skin care preparations, medical preparations containing active ingredients, etc.

Pending Publication Date: 2021-03-16
比奥尼克莱公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0030] The problem addressed by the present invention is to develop a method and composition for protection against the harmful effects of exposure to atmospheric pollutant molecules and / or exposure to ultraviolet radiation, which do not have the above-mentioned disadvantages

Method used

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  • Method for topical protection against atmospheric pollutant molecules and/or free radicals produced by exposure to ultraviolet radiation
  • Method for topical protection against atmospheric pollutant molecules and/or free radicals produced by exposure to ultraviolet radiation
  • Method for topical protection against atmospheric pollutant molecules and/or free radicals produced by exposure to ultraviolet radiation

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Embodiment Construction

[0182] figure 1 The mechanism of action of the composition of the invention is shown.

[0183] 1) Synthesis of colloidal Col-1 and Col-2

[0184] Percentages are given by weight of the composition

[0185] 1.1) wherein Col-1 and Col-2=ZnO

[0186] A zinc oxide precursor such as anhydrous zinc acetate (2%) and sodium hydroxide (1.5%) was mixed with a solvent or a solvent mixture containing ethanol (85%) and diethylene glycol (8%) and sealed in an autoclave . The solvent can also be benzyl alcohol, phenol, oleyl alcohol, butanol, propanol, isopropanol, water, tetrahydrofuran, ethanol, methanol, acetonitrile, toluene, PGMEA, PGPE, PGME, 2-methyl-1-propanol or Triethylene glycol monomethyl ether.

[0187] The reaction medium is placed at 60° C. for about 30 minutes under mechanical stirring until the salt dissolves. Water (2%) was then added. Cloudiness was observed, which indicated the onset of particle formation. The reaction was maintained at 65°C for one and a ha...

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Abstract

Disclosed is a method for topical protection against atmospheric pollutant molecules and ultraviolet (UV) radiation, comprising the steps of: a) producing a polymer matrix which is both repellent andanti-adhesive to atmospheric pollutant molecules, by means of a first biocompatible polymer (PB1); b) under the effect of the UV radiation, photocatalytically degrading the pollutant molecules havingpenetrated the polymer matrix by means of first semiconductor colloids (Col-1) onto which a second biocompatible polymer (PB2) has been grafted, which results in the formation of free radicals; c) neutralizing said free radicals by means of at least 2 antioxidants, which are: a first antioxidant in the form of second semiconductor colloids (Col-2) onto which the first antioxidant (AntiOx-1) has been covalently grafted, said second grafted colloids (Col-2) auto-regenerating under the effect of the UV radiation, and a second antioxidant agent (AntiOx-2) that is not present in the form of colloids grafted with an antioxidant; and d) stabilizing the polymer matrix by means of the second antioxidant agent (AntiOx-2).

Description

technical field [0001] The present invention relates to a method of providing local protection against harmful effects induced by exposure to pollutant molecules present in the atmosphere and / or exposure to ultraviolet radiation. [0002] The field of application of the invention relates in particular to cosmetics, more particularly to the fields of anti-pollution protection and sun protection. Background technique [0003] The skin is a multifunctional organ, and it is also the organ that extends the human body over the largest area. It performs a variety of fundamental functions, including protection from the external environment (from shock, pollution, pathogens, or indeed ultraviolet radiation), heat regulation, hormone synthesis (vitamin D, and various hormones), or indeed immune function . [0004] The skin is an organ that is constantly renewed and subjected to the effects of time. As the skin ages, the turnover of its cells slows down. The oldest cells build up a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61Q17/00A61K8/73A61K8/81A61K8/27A61K8/34
CPCA61K8/27A61K8/347A61K8/73A61K8/8176A61Q17/00A61K8/29A61K8/585A61K8/368A61K2800/522A61Q17/04
Inventor 昂·阿塔兰让-诺埃尔·托雷尔
Owner 比奥尼克莱公司
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