Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Kit for treating chemical injury of eyes based on injection of mesenchymal stem cells under conjunctiva

A quality stem cell and kit technology, applied in the field of biomedicine, can solve the problems of low drug concentration, infection, and short residence time, and achieve the effect of long residence time, less trauma and good effect.

Pending Publication Date: 2020-12-04
ZHONGSHAN OPHTHALMIC CENT SUN YAT SEN UNIV
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, eye drops stay on the ocular surface for a short time, and the drug concentration is low; amniotic membrane transplantation has the risk of reoperation after dissolution and infection

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 A kit for treating ocular chemical injury based on subconjunctival injection of mesenchymal stem cells

[0027] A kit for treating ocular chemical injury based on subconjunctival injection of mesenchymal stem cells, comprising the following components:

[0028] (1) Mesenchymal stem cell suspension: human bone marrow mesenchymal stem cell suspension, the concentration is 5×10 6 / ml;

[0029] (2) Anesthetic reagent: tetracaine hydrochloride eye drops;

[0030] (4) Ocular surface disinfection reagent: 0.5% povidone-iodine solution;

[0031] (3) Sterilized syringe: 1.0ml sterile syringe.

Embodiment 2

[0032] Example 2 A kit for treating ocular chemical injury based on subconjunctival injection of mesenchymal stem cells

[0033] A kit for treating ocular chemical injury based on subconjunctival injection of mesenchymal stem cells, comprising the following components:

[0034] (1) Mesenchymal stem cell suspension: human bone marrow mesenchymal stem cell suspension, the concentration is 1×10 6 / ml;

[0035] (2) Anesthetic reagent: tetracaine hydrochloride eye drops;

[0036] (4) Ocular surface disinfection reagent: 0.4% povidone-iodine solution;

[0037] (3) Sterilized syringe: 1.0ml sterile syringe.

Embodiment 3

[0038] Example 3 A kit for treating ocular chemical injury based on subconjunctival injection of mesenchymal stem cells

[0039] A kit for treating ocular chemical injury based on subconjunctival injection of mesenchymal stem cells, comprising the following components:

[0040] (1) Mesenchymal stem cell suspension: human bone marrow mesenchymal stem cell suspension, the concentration is 10×10 6 / ml;

[0041] (2) Anesthetic reagent: tetracaine hydrochloride eye drops;

[0042] (4) Ocular surface disinfection reagent: 0.6% povidone-iodine solution;

[0043] (3) Sterilized syringe: 1.0ml sterile syringe.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a kit for treating chemical injury of eyes based on injection of mesenchymal stem cells under conjunctiva. The kit for treating chemical injury of eyes based on injection of mesenchymal stem cells under conjunctiva comprises mesenchymal stem cells, an ocular surface anesthesia reagent, an ocular surface disinfection reagent and the like. By utilizing the kit disclosed by the invention, the chemical injury of eyes is treated based on injection of mesenchymal stem cells under conjunctiva, the active ingredients of the drug stay on the ocular surface for a long time and are high in concentration, the injury is small, an operation is not needed, and the kit has extremely low infection risk, is convenient to use and good in effect and has excellent application prospectsin the aspect of treatment of chemical injury of eyes.

Description

technical field [0001] The invention belongs to the technical field of biomedicine. More specifically, it relates to a kit for treating ocular chemical injury based on subconjunctival injection of mesenchymal stem cells. Background technique [0002] Eye chemical injury, that is, eye chemical injury, is mainly caused by strong acid (sulfuric acid, nitric acid, hydrochloric acid, etc.), strong alkali (lime, dilute ammonia solution, sodium hydroxide, etc.), dust or gas contacting the eye. . The most common is acid-base injury, the tissue reaction of the eye after acid-base chemical burn, which can be divided into mild, medium and severe burns in three different degrees. Occurs mostly in chemical plants, construction sites and laboratories. The severity of eye chemical injury is related to the type, concentration, dose, mode of action, injured site, contact time, contact area, temperature and pressure of chemical substances, and whether the treatment is reasonable and timely...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K35/28A61K31/245A61K31/79A61K9/00A61P27/02
CPCA61K35/28A61K31/245A61K31/79A61K9/0019A61K9/0051A61P27/02
Inventor 梁丹
Owner ZHONGSHAN OPHTHALMIC CENT SUN YAT SEN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com