Active silver ion colloid antibacterial agent and preparation method thereof

Abstract

The invention relates to an active silver ion colloid antibacterial agent applicable to infection control and wound heal promotion for human body surfaces, also relates to a preparation method of theactive silver ion colloid antibacterial agent, and belongs to the technical field of medicines for medical surgery. A finished liquid agent formed by the active silver ion colloid antibacterial agentcontains active silver ion powder, sodium alginate, dibasic acid, a penetrant, tartaric acid and purified water. The active silver ion colloid antibacterial agent and the preparation method thereof have the following advantages: firstly, a stabilizer with a permeation effect is adopted in a formula, can permeate through deep tissue of a wound, kill bacteria and endotoxins in deep parts and loosen,resolve and discharge necrotic tissue, pus and blood clots out of the body and contributes to shortening the wound heal time; secondly, the active silver ion colloid antibacterial agent does not cause obvious drug membranes or produce drug resistance by long-term use and can effectively shorten the treatment period; thirdly, the active silver ion colloid antibacterial agent causes no side effectson a patient and has no foreign smells or sensitization; and fourthly, the method comprises few process steps, has no harsh conditions and can adapt to mass production requirements.

Description

technical field [0001] The invention relates to an active silver ion colloidal antibacterial agent, which is suitable for controlling infection of human body surface wounds and promoting wound healing, and also relates to a preparation method of the active silver ion colloidal antibacterial agent, which belongs to the technical field of medical surgical medication. Background technique [0002] At present, the medicines for wound infection caused by burns, scalds, and open wounds are mainly sulfadiazine silver cream (also known as ointment) or suspension, and its active ingredients are mainly sulfadiazine except sulfadiazine. It is silver nitrate, which is widely used clinically. However, there are still the following deficiencies in clinical application: First, because this drug is not permeable, it is difficult to effectively kill the bacteria in the deep part of the wound, and it is easy to form an obvious drug film on the surface, resulting in a longer healing time of th...

AI Technical Summary

Problems solved by technology

Among the above three patented technical solutions, the first two belong to the category of non-medical clinical disinfectant solution, which is used for disinfection and sterilization of utensils such as tableware and bathware in people's daily life, as well as cleaning and sterilization of skin (CN1262101A) , not suitable for infection control such as burns, scalds, open wounds and wounds on the human body surface

And the third document (CN1110557A) belongs to traumatic treatment and has curative effect in surgical medicine and has occupied the pivotal position always, inferior then is to cause patient's local or systemic anaphylaxis frequent, drug-resistant bacterial strain increases day by day, has irritating smell, is harmful to human body. Inhibition of epidermal cell growth, adverse effects on renal function

However, this patented technical solution also has deficiencies. First, the treatment effect on the deep part of the wound is not ideal, because it is as impermeable as sulfadiazine silver cream; secondly, the formula has many raw materials; the processing conditions introduced are harsh

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