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Compound traditional Chinese medicine cataplasm for treating canine diarrhea and production process of cataplasm

A compound traditional Chinese medicine and production process technology, which is applied in the directions of drug combination, pharmaceutical formula, and medical preparations containing active ingredients, etc. Good prognosis and controllable effect of dosage and composition

Inactive Publication Date: 2019-10-15
ANHUI SCI & TECH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Antiviral treatment and antibacterial treatment mainly use injection or taking western medicine, and western medicine is highly toxic, and long-term use will cause drug residues in the body and even cause serious sequelae
The conditions to be considered in parasite treatment and fluid replacement therapy are more complicated, and detailed plans must be formulated according to individual conditions, which is time-consuming and labor-intensive

Method used

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  • Compound traditional Chinese medicine cataplasm for treating canine diarrhea and production process of cataplasm
  • Compound traditional Chinese medicine cataplasm for treating canine diarrhea and production process of cataplasm
  • Compound traditional Chinese medicine cataplasm for treating canine diarrhea and production process of cataplasm

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A kind of production of compound Chinese medicine cataplasm for treating dog diarrhea, the production technology of described compound Chinese medicine cataplasm comprises the following steps:

[0027] (1) Extraction of traditional Chinese medicine: Weigh 5g of pitted ebony, 25g of dried persimmon, 6g of myrobalan meat, 6g of coptis, 6g of turmeric, 15g of Humulus, 9g of pomegranate peel, 9g of bayberry root, and 6g of nutmeg, mix them with distilled water and boil on high heat After that, continue to decoct on low heat for 20 minutes, filter the medicinal liquid, add the medicinal residues to distilled water and boil again on high heat, then decoct on low heat for 20 minutes, filter while hot, and combine the two filtrates to obtain the compound Chinese medicinal liquid for later use;

[0028] (2) Preparation of Chinese medicinal extract: add the above-mentioned composite Chinese medicinal liquid to sodium benzoate while hot, place in an electric blast drying oven after...

Embodiment 2

[0033] According to the Chinese Pharmacopoeia Standards (2015 edition) quality standards, the appearance and shape evaluation, adhesion strength detection and weight difference evaluation of the cataplasm patch prepared in the above-mentioned Example 1 were carried out. To measure the adhesion strength, paste it on the phenolic material board with poultice, the adhesion area is 3cm×3cm, measure it with a tension meter, and record the data when the sample is pulled off the board. Stability test of poultice: place 4 samples in a constant temperature and humidity oven with a relative temperature of 37°C and a humidity of 75%, and measure the adhesion strength after taking out the samples.

[0034] The appearance evaluation results are as follows: the color of the cataplasm is dark brown, the appearance is a coin shape with a diameter of 3cm, the surface is shiny, the touch is slightly elastic and sticky, and it is applied on a square non-woven fabric with a side length of 7cm.

...

Embodiment 3

[0038] Detect the therapeutic effect and mechanism of the above-mentioned cataplasma, the detection method is as follows:

[0039] (1) Experimental animals: 12 adult healthy Chinese pastoral dogs, 6 males and 6 females. Immunization with pentavalent vaccine (produced by Wuxing Animal Health Pharmaceutical Factory in Jilin Province); deworming with ivermectin injection (Anhui Tianan Biotechnology Co., Ltd., approval number: Veterinary Medicine (2015) 120482645, license number: (2014) Veterinary Drug Production Certificate No. 12048). The test dogs were fed chicken oat dog food (produced by Xingtai Aopai Pet Food Co., Ltd.) for the whole period of time, once a day in the morning and evening, and drinking water was not restricted.

[0040] (2) Test method: 12 Chinese pastoral dogs were divided into control group and cataplasm administration group according to the principle of similar body weight, each group had three males and females, and all test dogs were fed with anhydrous s...

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Abstract

The invention provides a compound traditional Chinese medicine cataplasm for treating canine diarrhea and a production process of the cataplasm, and relates to the technical field of veterinary medicine preparation. The compound traditional Chinese medicine cataplasm is prepared jointly by a traditional Chinese medicine extractum and a cataplasm auxiliary material. The traditional Chinese medicineextractum consists of the following substances by weight: 15 parts of pitted smoked plum, 25 parts of dried persimmon, 6 parts of terminalia chebula, 6 parts of coptis chinensis, 6 parts of curcuma aromatica, 15 parts of humulus scandens, 9 parts of pomegranate peels, 9 parts of bayberry roots, and 6 parts of nutmeg. The cataplasm auxiliary material consists of the following substances by weight:3 parts of distilled water, 3 parts of gelatin, 4 parts of glycerin, 4 parts of sodium polyacrylate, 4 parts of arabic gum, 5 parts of polyethylene glycol 400, 0.3 part of azone, and 0.2 part of zincoxide. According to the present invention, the deficiencies of prior art are overcomed, the prepared medicine is osmotic delivered by abdominal adhesion of the cataplasm, the dosage of the cataplasmis controllable, the irritation to skin is small, the osmotic absorption effect is good, the blood medicine concentration is stable, the treatment prognosis is good, and the compound traditional Chinese medicine cataplasm is suitable for promotion and use.

Description

technical field [0001] The invention relates to the technical field of veterinary drug preparation, in particular to a compound traditional Chinese medicine cataplasm for treating dog diarrhea and a production process thereof. Background technique [0002] At present, the common methods for pet dogs to treat diarrhea are: ①Antiviral treatment: For pet dogs with viral diarrhea, antibiotics are given to treat secondary infections while antiviral drugs are used, and immunotherapy is given to improve the body's resistance. ② Antibacterial treatment: Antibacterial treatment is mainly used for bacterial diarrhea caused by bacteria, commonly used are penicillin, fosfomycin nuclear capsules, and gentamicin. ③Parasites: You need to take medicine to fight worms. According to the results of stool examination, you can determine which kind of parasite is the infection, and then use targeted medication. ④ Rehydration therapy: It can replenish the water and electrolytes of pet dogs in tim...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/70A61P1/12
CPCA61K9/7023A61K36/185A61K36/44A61K36/60A61K36/718A61K36/736A61K36/9066A61K47/42A61K2236/331A61K2236/39A61P1/12A61K2300/00
Inventor 李静丁晓东胡雨婷夏顺姚婧婷
Owner ANHUI SCI & TECH UNIV
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