A skull restoration body for inducing bone regeneration and a preparation method thereof

Abstract

The invention relates to the technical field of medical devices, in particular to a skull restoration body for inducing bone tissue regeneration and a preparation method thereof. The skull restorationbody has biological activity and comprises an inner inducing layer, a supporting layer and an outer inducing layer sequentially from the inside to the outside. The support layer is made of polyaryletherketone material which is equivalent to human bone strength, hardness and weight, and plays a supporting role. The inner inducing layer and the outer inducing layer are made of bioactive material, respectively arranged on the inner surface and the outer surface of the supporting layer, have good bioactivity and osteoinductivity, and can induce bone tissue regeneration. The support layer is provided with a plurality of mesh holes, and each mesh hole is filled with a bioactive material, which can promote the exchange of nutrients inside and outside the skull repair body, and is conducive to the growth of tissue. The preparation method of the skull prosthesis builds a digital model according to the skull data of the patient, so that the skull prosthesis and the skull defect part have high matching degree, and the operation difficulty is reduced.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a skull prosthesis for inducing bone tissue regeneration and a preparation method thereof. Background technique [0002] When a patient undergoes craniotomy due to traumatic brain injury or intracranial disease, etc., it usually causes a skull defect. The skull defect makes the brain tissue lose its protective barrier and is easy to be injured. When the defect is large, it is accompanied by dizziness, headache, depression, and irritability. , anxiety and other symptoms, and affect the appearance, causing greater psychological harm to patients. With the help of cranial repair surgery and cranial prosthetics, the skull defect area can be repaired, so as to achieve the purpose of protecting brain tissue, reducing complications, and restoring the patient's appearance. [0003] At present, the materials used to make cranial prostheses mainly include natural biological materia...

AI Technical Summary

Problems solved by technology

Metal materials include tantalum, titanium alloy or stainless steel, etc. The repair is a permanent implant, and long-term foreign body stimulation may cause complications and easily lead to abnormal growth of new bone

Non-metallic materials include plexiglass, bone cement and their composite materials, etc. Bone cement stimulates brain tissue, and is easy to deform and loosen after surgery. Plexiglass has low strength, fragility, aging and poor tissue compatibility.

Chinese patent CN102490350A discloses a plan to use PEEK as a skull repair material. PEEK has good biocompatibility and excellent mechanical properties, but it is a biologically inert material, which is not conducive to the adhesion and growth of cell tissues and affects wounds. heal

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