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Glucan-glucomannan composition

A technology of glucomannan and glucan, used in food science, drug combination, plant raw materials, etc.

Inactive Publication Date: 2018-12-07
袁暾
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As for the construction of complex systems, function-oriented adjustments, the introduction of new functional substances and the improvement of application forms to further promote its application in food, medicine, cosmetics, medical devices, daily chemicals and industries, etc., There are no related reports, and solving these problems requires a lot of creative work

Method used

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  • Glucan-glucomannan composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The selenium-enriched glutathione-loaded glucan-glucomannan composite colloid contains 0.3% β-glucan and 0.5% glucomannan by mass. β-glucan with a molecular weight range of 10,000-100,000 Daltons was prepared as a solution with a mass percentage of 0.6%, fully stirred and heated to 37°C for 30 minutes; the molecular weight range of 10,000-100,000 Daltons based on polymer The glucomannan prepared from selenium-enriched konjac prepared a solution with a mass percentage of 1.0%, fully stirred and heated to 48°C; the prepared β-glucan solution was slowly added to the above-mentioned thermal insulation at a final ratio of 1:1. In the glucomannan solution, add reduced glutathione to make the final concentration 5 mg / mL, stir well, and keep for 30 minutes; slowly cool down to room temperature to obtain selenium-enriched glutathione dextran-glucomannan Sugar complex colloids are used for skin beauty.

Embodiment 2

[0018] The selenium-enriched glucan-glucomannan composite gel contains 3.6% β-glucan and 4.8% glucomannan by mass. 2,000,000 Daltons of bacterial-derived β-glucan (pre-sterilized) was prepared into a solution with a mass percentage of 7.2%, an appropriate amount of pre-sterilized selenium-enriched yeast powder was added to the solution, and the temperature was fully stirred and heated to 50 ° C. hour; take sterile glucomannan with a molecular weight range of 600,000-1,200,000 daltons based on the polymer to prepare a solution with a mass percentage of 9.6%, stir well, adjust the pH value to 10.5 with 0.5mol / L NaOH solution, fully Stir and heat up to 82°C; slowly add the prepared β-glucan solution to the above-mentioned glucomannan solution in a 1:1 final ratio, stir well, and adjust the pH of the system to 6.8-7.2 with PBS buffer , and the temperature is slowly lowered to room temperature at a rate of less than 1° C. per minute after being incubated for 2 hours to obtain a sel...

Embodiment 3

[0020] The dextran-glucomannan composite membrane, the preparation method includes: taking β-glucan with a molecular weight range of 10,000-2,000,000 Daltons to prepare a solution with a mass percentage of 1.0%, fully stirring and heating up to 45 ℃, incubated for 1 hour; take glucomannan with a molecular weight range of 10,000-1,200,000 Daltons based on the polymer to prepare a solution with a mass percentage of 2.0%, fully stir and heat up to 65 ℃; The prepared β-glucan solution is slowly added to the above-mentioned glucomannan solution that has been kept warm, fully stirred, and after 1 hour of incubation, the mixed system is used for casting and film forming to obtain a dextran-glucomannan composite film. For edible food inner packaging applications.

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Abstract

The invention relates to a glucan-glucomannan composition for medical instruments, biological medicines, beauty and cosmetics and food health. The glucan-glucomannan can provide synergy for not only system formation, but also effect. The glucan-glucomannan composition has the main beneficial effects that various drawbacks in independent application of glucan and glucomannan are improved, the technical problems such as composite-system construction, function-oriented adjustment, introduction of new functional substances and application-form improvement and the like are solved, the whole property and the use convenience of the glucan-glucomannan system are improved, and on the basis of functional synergy, the application expansion and market development are greatly promoted and possible application in the aspects of foods, medicines, cosmetics, medical instruments, daily chemicals and industry is pushed; especially, good properties of the composite system used for final purposes in various forms are ensured, more improvement of the biological application properties by means of carrying functional molecules and the like are guaranteed.

Description

technical field [0001] The present invention relates to a glucan-glucomannan compound used for medical equipment, biomedicine, cosmetic makeup and food health care; wherein the glucan-glucomannan is not only constituted in the compound system, but also has the function of Through simple adjustment and post-processing, this complex platform can be derived into a variety of different forms, carrying different functional substances to meet a wider range of practical needs. Background technique [0002] Because of its many unique biological activities, β-1,3-D-glucan has been widely valued since its discovery, and its research in biomedicine has continued to deepen. Existing studies have shown that, as an important multifunctional natural polysaccharide, glucan has unique functions in anti-tumor, cholesterol-lowering, anti-infection, endurance enhancement, radiation exposure protection, wound repair, surgical care and septic shock treatment. The value of its-based health food, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/04A61K8/64A61K8/23A61Q19/00A61Q19/08A61K31/716A61K33/04A61K38/06A61K36/287A61K9/06A61K9/70A61P17/02A61P39/06A61P39/02A61L15/28A61L15/40A61L15/42A23L33/125
CPCA23L33/125A61K8/042A61K8/23A61K8/64A61K8/73A61K9/06A61K9/7023A61K31/716A61K33/04A61K36/287A61K38/06A61K2800/5922A61L15/28A61L15/40A61L15/425A61L2300/232A61L2300/30A61P17/02A61P39/02A61P39/06A61Q19/00A61Q19/08A61K2300/00C08L5/02
Inventor 袁暾
Owner 袁暾
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