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Spray

A technology of spray and permeation aid, which is applied in the field of cosmetics and skin care products, can solve problems such as poor skin care effect, accelerated cell metabolism and peeling, and increased allergy rate, so as to improve skin permeability, improve skin barrier function, The effect of increasing the moisture content of the skin

Inactive Publication Date: 2018-11-27
SUZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if ceramide is used alone, there are two problems: on the one hand, free natural ceramide is a messenger of apoptosis, and excessive use will accelerate cell metabolism and detachment.
[0014] Although the Chinese patent application number 200980138471.6 provides a stable ceramide dispersion, which can effectively improve the skin penetration of ceramide, but adding more surfactants affects its safety and stability
The Chinese patent with the application number 20101014497.8 selects the combination of diguanosine tetraphosphate, nicotinamide and hyaluronic acid to improve skin moisture content, increase elasticity and whitening, but the delivery effect of the main ingredients is not as good as the method of simple liquid application Poor, not conducive to skin absorption
In addition, Chinese patents CN201510620456, CN201510620460, and CN201610358625 respectively disclose an anti-wrinkle and whitening toner, an anti-allergic moisturizing toner, and a beauty toner. These compositions all contain hyaluronic acid, nicotinamide and ceramide, but the preparation The process uses high temperature to dissolve, and the three components of hyaluronic acid, niacinamide and ceramide are sensitive to high temperature, resulting in a decrease in effective content. In addition, the skin care effect is not good if the method of pure liquid application is used, and the increase of related substances may cause lead to an increase in allergies

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] This example provides a spray F1 used as skin care water, which includes the following components: 50 mg of hyaluronic acid, 300 mg of nicotinamide, 500 mg of ceramide, and 10 mL of pure water. Its preparation method is as follows:

[0039] Weigh the prescribed amounts of hyaluronic acid, niacinamide and ceramide respectively, add pure water, stir at high speed to fully dissolve the raw materials, and let stand to obtain the mixed solution. Fill the mixture into a container with an ultrasonic spray device to obtain a spray. When in use, with the help of ultrasonic vibration, the mixed liquid is sprayed out in the form of mist, and the sprayed droplets are nano-scale droplets.

[0040] In order to serve as a control, the mixed solution is filled in a common bottle, and used as a common skin care water, and is directly applied to the skin surface when used.

Embodiment 2

[0042] This embodiment provides a spray F2, including the following components: 50 mg of hyaluronic acid, 300 mg of nicotinamide, 500 mg of ceramide, and 10 mL of glycerin aqueous solution, wherein the mass fraction of glycerin in the glycerin aqueous solution is 10%. Its preparation method is as follows:

[0043] Respectively weigh the hyaluronic acid, nicotinamide and ceramide of the prescribed amount, add glycerin aqueous solution, stir at high speed to fully dissolve the raw materials, and let stand to obtain the mixed solution. Fill the mixture into a container with an ultrasonic spray device to obtain a spray. When in use, with the help of ultrasonic vibration, the mixed liquid is sprayed out in the form of mist, and the sprayed droplets are nano-scale droplets.

[0044] In order to serve as a control, the mixed solution is filled in a common bottle, and used as a common skin care water, and is directly applied to the skin surface when used.

Embodiment 3

[0046] This embodiment provides a spray F3, which includes the following components: 50 mg of hyaluronic acid, 300 mg of nicotinamide, and 10 mL of pure water. Its preparation method is as follows:

[0047] Weigh the prescribed amount of hyaluronic acid and nicotinamide respectively, add pure water, stir at high speed to fully dissolve the raw materials, and let stand to obtain the mixed solution. Fill the mixture into a container with an ultrasonic spray device to obtain a spray. When in use, with the help of ultrasonic vibration, the mixed liquid is sprayed out in the form of mist, and the sprayed droplets are nano-scale droplets.

[0048] In order to serve as a control, the mixed solution is filled in a common bottle, and used as a common skin care water, and is directly applied to the skin surface when used.

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Abstract

The invention relates to a spray. The spray comprises at least two of hyaluronic acid, niacinamide and ceramide and further comprises aqueous-phase solvents. The hyaluronic acid accounts for 0.01-2% of the total weight of the spray, the niacinamide accounts for 0.5-8% of the total weight of the spray, and the ceramide accounts for 0.1-10% of the total weight of the spray. The spray has the advantages that the spray is a skin whitening, water replenishing and anti-aging cosmetic composition, at least two of the hyaluronic acid, the niacinamide and the ceramide can be permeated into deep layersof skin in nanometer-size or micrometer-size fog-drop forms, accordingly, skin aging procedures can be improved, the water content of the skin can be increased, and the elasticity of the skin can be kept.

Description

technical field [0001] The invention relates to the fields of skin care products and cosmetics, in particular to a spray. Background technique [0002] With the increase of physiological age and long-term exposure to external stimuli, the skin barrier is damaged, the loss of water cannot be controlled, the skin will age, and even cause a variety of skin diseases. The pursuit of modern life quality has made consumers pay more attention to skin care, hoping that skin care products can achieve whitening, moisturizing and anti-aging effects. [0003] Professor Peter M.Elias of the University of California in the United States pioneered the "brick wall structure" theory of the skin barrier. "Brick wall" represents keratinocytes, and "mortar" refers to lipids (including ceramides, fatty acids, and cholesterol) in the gap between keratinocytes. , "brick wall" and "mortar" make the epidermis form a firm structure, restrict the flow of water inside and outside the cells and between ...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/68A61K8/67A61K8/04A61Q19/02A61Q19/00A61Q19/08
CPCA61K8/046A61K8/675A61K8/68A61K8/735A61K2800/412A61K2800/413A61Q19/00A61Q19/02A61Q19/08
Inventor 曹青日黄豪雁骆媛
Owner SUZHOU UNIV
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