A visible light-catalyzed dehalogenation method of halogenated aromatic hydrocarbons without photoredox catalyst

Abstract

The invention discloses a visible light catalysis method for dehalogenation of aryl halide without the need of a photooxidation reduction catalyst, and belongs to the technical field of visible lightcatalysis organic synthesis. The method comprises the following steps that firstly, the aryl halide is weighed and placed in a reaction vessel, and a solvent is added; secondly, the reaction vessel isfilled with nitrogen for oxygen removal for 0-50 minutes, and alkali is added during the oxygen removal period; thirdly, the reaction vessel is sealed and placed over a light emitting diode with thewavelength of 400-500 nm and the power of 0.5-30 W for irradiation, and reacting is conducted for 3-48 hours at room temperature under the condition of stirring and then finished. By means of the method, the photooxidation reduction catalyst which is high in price or complex in synthesis is not needed, reacting can be achieved under the condition of the room temperature or under a mild condition,a reaction substrate is high in adaptability, and the reaction yield is high.

Description

technical field [0001] The invention belongs to the technical field of visible light catalyzed organic synthesis, and in particular relates to a visible light catalyzed dehalogenation method for halogenated aromatic hydrocarbons without a photoredox catalyst. Background technique [0002] It is a major mission for chemists to develop feasible visible light photocatalysis methods and explore the scientific principles. An ideal visible-light photocatalytic method needs to meet the following conditions: high reaction efficiency, wide substrate adaptability, and good functional group selectivity. In addition, from the perspective of industrial scale production, the developed method should also meet the characteristics of easy operation and low production cost; at the same time, it is necessary to avoid the use of photoredox catalysts that are expensive or have complicated chemical synthesis steps. [0003] In recent years, scientists have developed a series of visible light cat...

AI Technical Summary

Problems solved by technology

However, the introduction of visible light also brings new problems. In the reported visible light-catalyzed reactions (including dehalogenation and carbon-carbon coupling) using halogenated aromatic hydrocarbons as reaction substrates, noble metal complexes must be used. or photosensitizers as photoredox catalysts

These photoredox catalysts often have problems such as expensive price or complex synthesis. More importantly, the introduction of photoredox catalysts will increase the difficulty of subsequent separation and purification operations, thereby affecting the actual yield of the reaction.

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