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Cell preparation laboratory design scheme

A laboratory design, cell technology, applied in the direction of small buildings, etc., can solve the problems that cannot meet the micro-cell experiment workflow and environmental requirements, and the layout is disorderly, etc., to achieve the effect of small footprint, clear sewage flow, and reasonable logistics

Active Publication Date: 2018-04-27
北京远教教育科技中心 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the improvement of science and technology in our country, cell preparation technology has also been improved, and cell preparation is used in a wide range of fields; such as drug research and development, such as new drug screening, vaccines, genetic engineering drugs, cell engineering drug research and development, monoclonal antibody preparation, etc. ; basic research, such as drug action mechanism, gene function, disease occurrence mechanism, etc.; biopharmaceuticals, such as vaccine production: such as viral vaccines (hepatitis virus vaccines, AIDS vaccines, etc.), polypeptide vaccines, tumor vaccines), etc.; genetic engineering drug production : such as EPO, etc.; production of antibody drugs and gene therapy drugs; production of cell engineering drugs: some biologically active polypeptides and biologically active substances in biological cells; use cell method to determine the activity of biologically active substances in vitro; and predict their drug in vivo However, the cell preparation laboratory requires high requirements. The cell preparation laboratory consists of a main laboratory, an auxiliary room, and an isolation device. The main laboratory is also called the environment of the core area. Requirements: cleanliness level, number of air changes, minimum pressure difference relative to the atmosphere, minimum pressure difference Pa of adjacent rooms connected to the outdoor direction, temperature and humidity, noise, average illuminance, tightness of enclosure structure, national standard (GB50346- 2011) have clear standard requirements; these rooms and isolation devices need a reasonable layout in order to improve work efficiency; the layout of the prior art is chaotic, and the relative positions between each functional room and the isolation device are randomly arranged, which cannot meet the requirements of microcell experiments. Workflow and Environmental Requirements

Method used

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Examples

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Embodiment 1

[0021] see figure 1 As shown, the present invention provides a design scheme of a cell preparation laboratory, including a preparation room 1, a logistics room 5, a treatment room 2, a human flow room 4 and a monitoring room 6 are sequentially arranged around the preparation room 1; the monitoring room A first preparation area 7 is provided between 6 and the preparation room 1; a second preparation area 3 is provided between the human flow chamber 4 and the preparation room 1; please refer to figure 2 As shown, the side adjacent to the processing chamber 2 inside the preparation chamber 1 is provided with an adjacent culture chamber 12 and a culture medium preparation room 14, the culture chamber 12 is adjacent to the logistics chamber 5, and the The culture medium preparation room 14 is adjacent to the second preparation area 3; an aseptic operation room 15 and a fourth buffer room 16 are arranged on the side adjacent to the first preparation area 7 inside the preparation ro...

Embodiment 2

[0025] see figure 2 and image 3 As shown, as a technical optimization solution of the present invention, the inside of the flow room 4 is sequentially provided with a first buffer room 41 leading to the first preparation area 7, a changing room 42, an ultraviolet sterilizing room 43 and a first Airlock chamber 44; The inside of described human flow chamber 4 is also provided with the second buffer room 45 leading to the second preparation area 3, the flushing room 47 and the second airlock chamber 48 in sequence; The second buffer room 45 and The first buffer room 41, the dressing room 42 are adjacent to the ultraviolet sterilizing room 43, the other side of the second buffer room 45 is provided with a drying room 46, and the washing room 47 is connected to the second buffer room 45 and the drying room. The dry room 46 is adjacent, the second airlock chamber 48 is adjacent to the first airlock chamber 44 and the second preparation area 3 , and the connected rooms are provid...

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Abstract

The invention discloses a cell preparation laboratory design scheme. According to the design scheme, the laboratory comprises a preparation chamber, and a logistics chamber, a treatment chamber, a human flow chamber and a monitoring chamber are arranged sequentially around the preparation chamber; a first preparation area is arranged between the monitoring chamber and the preparation chamber; a second preparation area is arranged between the human flow chamber and the preparation chamber; a cultivation chamber and a culture medium preparation room are arranged on the side, adjacent to the treatment chamber, of the inside of the preparation chamber, the cultivation chamber is adjacent to the culture medium preparation chamber, the cultivation chamber is adjacent to the logistics chamber, and the culture medium preparation chamber is adjacent to the second preparation area; the side, adjacent to the first preparation area, of the inside of the preparation chamber is provided with a sterile operation chamber and a fourth buffering chamber, the sterile operation chamber is adjacent to the logistics chamber and the cultivation chamber, and the fourth buffering chamber is adjacent to thesterile operation chamber and the second preparation area; a washing chamber and a disinfection chamber are arranged between the fourth buffering chamber and the cultivation chamber and the culture medium preparation chamber, the washing chamber is adjacent to the disinfection chamber, the washing chamber is adjacent to the sterile operation chamber, and the disinfection chamber is adjacent to the second preparation area.

Description

technical field [0001] The invention belongs to the field of architectural design; in particular, it relates to a design scheme of a cell preparation laboratory. Background technique [0002] With the improvement of science and technology in our country, cell preparation technology has also been improved, and cell preparation is used in a wide range of fields; such as drug research and development, such as new drug screening, vaccines, genetic engineering drugs, cell engineering drug research and development, monoclonal antibody preparation, etc. ; basic research, such as drug action mechanism, gene function, disease occurrence mechanism, etc.; biopharmaceuticals, such as vaccine production: such as viral vaccines (hepatitis virus vaccines, AIDS vaccines, etc.), polypeptide vaccines, tumor vaccines), etc.; genetic engineering drug production : such as EPO, etc.; production of antibody drugs and gene therapy drugs; production of cell engineering drugs: some biologically activ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): E04H1/12
CPCE04H1/12
Inventor 曹毓琳刘俊江时兆田白志惠
Owner 北京远教教育科技中心
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