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Hyperostosis cold compress paste and preparation method thereof

A technology for bone hyperplasia and mass fraction, which is used in bone diseases, pharmaceutical formulations, cooling appliances for treatment and treatment, etc. Inflammation and purulent spread, increased skin contact, reduced local blood flow

Inactive Publication Date: 2017-10-27
四川利佰生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Most of the traditional bone hyperplasia plasters only have analgesic effect and no cold compress effect. The production method is as follows: melt the hot melt adhesive as a matrix, add an organic solvent and mix it with various raw materials to make a coating for heating and coating. There are chemical solvents in it. Residue, the production process is cumbersome and there are flammable safety hazards, the product is irritating to the skin when it is used, and it cannot be pasted again after being peeled off; more specifically, it has the following defects:
[0006] 2. The stickiness of the hot sol of the traditional bone hyperplasia patch is difficult to last, which leads to the sticking time of the patch is not durable, and it can only be pasted once, and cannot be peeled off repeatedly;
[0007] 3. The preparation process of traditional bone hyperplasia stickers is complicated, and there are hidden dangers of inflammability and explosion;
[0008] 4. The traditional bone hyperplasia patch is dissolved with a large amount of organic solvent, which is irritating to the skin

Method used

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  • Hyperostosis cold compress paste and preparation method thereof
  • Hyperostosis cold compress paste and preparation method thereof
  • Hyperostosis cold compress paste and preparation method thereof

Examples

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Effect test

Embodiment 1

[0037] The gel drug layer 2 includes the following raw materials in parts by mass: 20-50 parts of sodium polyacrylate, 15-30 parts of carbomer, 150-270 parts of glycerin, 1-10 parts of aluminum glycolate, 1-10 parts of tartaric acid, purified 380-450 parts of water, 90-150 parts of medical borneol, 60-100 parts of camphor, 60-100 parts of diclofenac, 30-50 parts of menthol, 30-50 parts of belladonna liquid extract, 30-50 parts of clove oil, propylene glycol 21-35 parts, glycerin 21-35 parts, medical azone 21-35 parts, diphenhydramine 21-35 parts, peppermint oil 15-24 parts, capsaicin 1-1.6 parts.

[0038] The mass parts of the above-mentioned raw materials can be adjusted arbitrarily within the above-mentioned range in specific applications. The principle of adjustment is based on the different degrees of demand of patients for the corresponding medicinal effects of each raw material, as well as the different degrees of demand for viscosity and permeability. The difference in ...

Embodiment 2

[0046] The gel drug layer 2 includes the following raw materials in parts by mass: 20-50 parts of sodium polyacrylate, 15-30 parts of carbomer, 150-270 parts of glycerin, 1-10 parts of aluminum glycolate, 1-10 parts of tartaric acid, purified 380-450 parts of water, 90-150 parts of medical borneol, 60-100 parts of camphor, 60-100 parts of diclofenac, 30-50 parts of menthol, 30-50 parts of belladonna liquid extract, 30-50 parts of clove oil, propylene glycol 21-35 parts, 21-35 parts of glycerin, 21-35 parts of medical azone, 21-35 parts of diphenhydramine, 15-24 parts of peppermint oil, 1-1.6 parts of capsaicin, 50-100 parts of Millennium Health Powder 40-80 parts of Clematis powder, 10-30 parts of Golden Retriever Dog Ridge powder, 10-30 parts of Cnidinia powder.

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PUM

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Abstract

The invention discloses a hyperostosis cold compress paste which comprises a backing layer, a gel drug layer and an anti-bonding layer, wherein the gel drug layer contains the following raw materials: sodium polyacrylate, carbomer, glycerol, dihydroxyaluminum aminoacetate, tartaric acid, purified water, medical borneol, camphor, diclofenac sodium, menthol, atropa belladonna fluid extract, clove oil, propylene glycol, glycerol, medical azone, diphenhydramine, oleum menthae and capsaicin. The invention also discloses a preparation method for the hyperostosis cold compress paste. The method comprises the following steps: preparing a gel drug and then coating the backing layer with the gel drug by machine so as to form a gel drug layer; covering the gel drug layer with the anti-bonding layer; cutting, puncturing and slicing, thereby acquiring the hyperostosis cold compress paste. No organic solvent is added into the bruise cold compress paste disclosed by the invention; the cold compress paste can be directly coated and does not need to be heated; the technology is simple and no chemical residue exists; the cold compress paste is free from irritability and stimulation, is high in drug loading capacity and moisture retention, has high compatibility with skin, is anti-ageing, has excellent weather fastness and lasting viscidity and can be repeatedly uncovered and pasted.

Description

technical field [0001] The invention relates to a biological plaster and a preparation method thereof, in particular to a bone hyperplasia cold compress and a preparation method thereof. Background technique [0002] Osteoarthritis is also called proliferative osteoarthritis, osteoarthritis (OA), degenerative joint disease, senile arthritis, and hypertrophic arthritis. Degeneration, the formation of bone spurs on the edge of the joint, hypertrophy of the synovium, and other changes, resulting in bone destruction, causing secondary bone hyperplasia, leading to joint deformation, and a disease that causes joint pain and limited mobility when subjected to abnormal loads . [0003] Bone hyperplasia patch is a kind of medicinal patch that achieves the purpose of softening hard masses, dispelling blood stasis and reducing swelling, relaxing tendons and activating collaterals, dispelling cold and relieving pain through local application, acupoint application and ointment applicati...

Claims

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Application Information

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IPC IPC(8): A61K36/81A61K36/888A61K9/70A61K47/32A61K47/14A61K47/10A61P19/08A61F7/02A61K31/045A61K31/125A61K31/135A61K31/165A61K31/196A61K31/55
CPCA61F7/02A61F2007/0226A61F2007/0263A61K9/0004A61K9/7061A61K31/045A61K31/125A61K31/135A61K31/165A61K31/196A61K31/55A61K36/12A61K36/234A61K36/534A61K36/61A61K36/716A61K36/81A61K36/888A61K2236/333A61K2300/00
Inventor 杨廷章胡玉霞张钟文
Owner 四川利佰生物科技有限公司
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