Rheumatism cold compress paste and preparation method thereof

Abstract

The invention discloses a rheumatism cold compress paste which comprises a backing layer, a gel drug layer and an anti-bonding layer, wherein the gel drug layer contains the following raw materials: sodium polyacrylate, carbomer, glycerol, dihydroxyaluminum aminoacetate, tartaric acid, purified water, medical borneol, camphor, diclofenac sodium, menthol, atropa belladonna liquid extract, ginger oil, propylene glycol, glycerol, medical azone, diphenhydramine, oleum menthae and capsaicin. The invention also discloses a preparation method for the rheumatism cold compress paste. The method comprises the following steps: firstly, preparing a gel drug, and then coating the backing layer with the gel drug by machine so as to form the gel drug layer, coating the gel drug layer with the anti-bonding layer, cutting, puncturing and slicing, thereby acquiring the bruise cold compress paste. No organic solvent is added into the rheumatism cold compress paste disclosed by the invention; the rheumatism cold compress paste can be directly used for coating and does not need to be heated; the technology is simple and no chemical residue exists; the rheumatism cold compress paste is free from irritability and stimulation, is high in drug loading capacity and moisture retention, has high compatibility with skin, is anti-ageing, has excellent weather fastness and lasting viscidity and can be repeatedly uncovered and pasted; the production cost is lower.

Description

technical field [0001] The invention relates to a biological plaster and a preparation method thereof, in particular to a rheumatic cold compress and a preparation method thereof. Background technique [0002] Rheumatism is a group of diseases mainly invading joints, bones, muscles, blood vessels and related soft or connective tissues, most of which are autoimmune diseases. The onset is mostly hidden and slow, the course of the disease is long, and most of them have genetic predisposition. Diagnosis and treatment are difficult; different autoantibodies can be detected in the blood, which may be related to different HLA subtypes; there is a good short-term response to non-steroidal anti-inflammatory drugs (NSAIDs), glucocorticoids and immunosuppressants or long-term remission. [0003] Fengshi plaster is a kind of medical plaster with auxiliary therapeutic effect on pain caused by wind-cold-damp arthralgia, joint pain, hand and foot spasm, rheumatoid arthritis, gout, etc. I...

AI Technical Summary

Problems solved by technology

[0004] Most of the traditional rheumatic plasters only have analgesic effect and no cold compress effect. The production method is as follows: melt the hot melt adhesive as a base, add an organic solvent and mix it with various raw materials to make a coating and then apply it by heating. There are chemical solvent residues in it. The production process is cumbersome and there are flammable safety hazards. The product is irritating to the skin when it is used, and it cannot be pasted again after being peeled off; more specifically, it has the following defects:

[0006] 2. The stickiness of the hot sol of the traditional rheumatism patch is difficult to last, which leads to the sticking time of the patch is not durable, and it can only be pasted once, and cannot be peeled off repeatedly;

[0007] 3. The preparation process of traditional rheumatism paste is complicated, and there are hidden dangers of flammability and explosion;

[0008] 4. The traditional rheumatism plaster is dissolved with a large amount of organic solvent, which is irritating to the skin

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