A kind of preparation method of ibuprofen aerated cotton candy
A technology of inflating marshmallow and granulated sugar, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve problems such as low oral bioavailability, poor patient compliance, and bad taste , to cover the taste of the drug well, enhance the sweetness, and protect the gastric mucosa
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specific Embodiment approach 1
[0023] Specific embodiment one: the preparation method of a kind of ibuprofen aerated marshmallow of the present embodiment is to carry out according to the following steps:
[0024] One, sieving: take the ibuprofen crude drug, pass through a 200-mesh sieve; corn starch, pass through a 80-mesh sieve, and take the part under the sieve for later use;
[0025] 2. Weighing: Weigh 100-150 parts of ibuprofen raw material drug powder, 100-150 parts of starch, 600-900 parts of granulated sugar, 400-600 parts of glucose, 100 parts ~300 parts of gelatin powder, 1~3 parts of sodium alginate, 1~3 parts of stevioside, 1~3 parts of lemon essence, 6~8 parts of citric acid, 10~15 parts of table salt, 100~ 400 parts of water, 1 to 3 parts of sorbitol and 0.05 to 0.08 parts of tartrazine;
[0026] 3. Sol: Add the gelatin powder and sodium alginate weighed in step 2 into water at 65°C to 75°C and stir for 10 to 30 minutes to obtain a gelatin mixed solution; put the gelatin mixed solution in a v...
specific Embodiment approach 2
[0038]Specific embodiment 2: The difference between this embodiment and specific embodiment 1 is that in step 2, 100-120 parts of ibuprofen crude drug powder, 100-120 parts of cornstarch, 600-900 parts of Sugar, 500-600 parts of glucose, 100-200 parts of gelatin powder, 1-2 parts of sodium alginate, 1-2 parts of stevioside, 1-2 parts of lemon essence, 6-7 parts of citric acid , 10-12 parts of table salt, 200-300 parts of water, 1-2 parts of sorbitol and 0.05-0.07 parts of tartrazine. Others are the same as in the first embodiment.
specific Embodiment approach 3
[0039] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is: described in step two, weigh 100~110 parts of ibuprofen crude drug powder, 100~110 parts of cornstarch, 700~900 parts sugar, 550-600 parts of glucose, 110-200 parts of gelatin powder, 1-2 parts of sodium alginate, 1-2 parts of stevioside, 1-2 parts of lemon essence, 6.5-7.5 parts of lemon acid, 10-11 parts of salt, 150-300 parts of water, 1-2 parts of sorbitol, and 0.05-0.07 parts of tartrazine. Others are the same as in the first or second embodiment.
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