Dispersible tablet of maca, preparation method and application thereof
A technology for dispersible tablets and maca, applied in the field of health care, can solve the problems of poor drug compliance, limited application of maca, disintegration speed, solubility and bioavailability of chewable tablets or capsules, etc. Dissolution time, rapid dissolution, and improved dispersion uniformity
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Embodiment 1
[0026] Example 1 Preparation of Maca Dispersible Tablets of the Invention
[0027] Mix 580g of maca powder, 80g of cross-linked polyvinylpyrrolidone, 0.45g of sodium lauryl sulfate, 40g of maltodextrin, 280g of microcrystalline cellulose, and 10g of aspartame. A soft material made of 80% ethanol is passed through a 14-mesh sieve for granulation, dried at 60°C for 2 hours, passed through a 20-mesh sieve for granulation, and then 10 g of magnesium stearate is added. Mix and press to prepare maca dispersible tablets of the present invention.
Embodiment 2
[0028] Example 2 Preparation of Maca Dispersible Tablets of the Invention
[0029] Mix 680g of maca powder, 150g of low-substituted hydroxypropyl cellulose, 0.45g of sodium lauryl sulfate, 10g of mannitol, 140g of microcrystalline cellulose, and 10g of stevia, and add 5% polyvinylpyrrolidone to 80% The soft material is made from the ethanol solution of 5%, passed through a 14-mesh sieve for granulation, dried at 60°C for 2h, passed through a 20-mesh sieve for granulation, and then added 10g of talc. Mix and press to prepare maca dispersible tablets of the present invention.
Embodiment 3
[0030] Example 3 Preparation of Maca Dispersible Tablets of the Invention
[0031] Mix 550g of maca powder, 200g of sodium carboxymethylcellulose, 11.25g of poloxamer, 89g of lactose, 500g of microcrystalline cellulose, and 25g of sucrose, mix well, and add 70% ethanol with a wet volume percentage to make soft Granulate through a 14 mesh screen, dry at 60°C for 2 hours, pass through a 20 mesh screen, and then add 10g magnesium stearate. Mix and press to prepare maca dispersible tablets of the present invention.
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