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A kind of preparation method of Angelica dahurica decoction pieces

A technology of Angelica dahurica and decoction pieces, which is applied in the field of preparation of Angelica dahurica decoction pieces, can solve the problems of high bioavailability, low toxicity and side effects, and achieve the effects of accelerated dissolution, easy absorption, and enhanced drug efficacy

Inactive Publication Date: 2011-11-30
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no report of directly preparing the fresh product of Angelica dahurica into decoction pieces with good absorption in vivo, high bioavailability, and low toxic and side effects by ultrafine pulverization

Method used

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  • A kind of preparation method of Angelica dahurica decoction pieces
  • A kind of preparation method of Angelica dahurica decoction pieces
  • A kind of preparation method of Angelica dahurica decoction pieces

Examples

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Effect test

Embodiment 1

[0022] Embodiment 1 The preparation of Angelica dahurica superfine powder of the present invention

[0023] Preparation method: take fresh Angelica dahurica, wash, slice or dice directly, after drying, crush into coarse powder, dry at 60°C for 14 hours, and pulverize at 12°C-16°C with Bailey ultrafine grinder (BFM-100B) 20 minutes and serve. Grinding particle size: 300 mesh, 350 mesh, 400 mesh, 500 mesh, the yield is 95-98%.

[0024] The above-mentioned drying method for sliced ​​or diced fresh products of Angelica dahurica can adopt any one of the following methods:

[0025] (1) sun exposure method

[0026] Clean the fresh Angelica dahurica and cut it into transverse slices with a thickness of 5-6 mm with a special slicer. Spread the fresh slices on a bamboo mat, place them in the sun outdoors, and place them in a ventilated and dry place indoors on cloudy and rainy days. Turn it over frequently during the drying process to dry as soon as possible and prevent mildew.

[0...

Embodiment 2

[0038] Embodiment 2 Preparation of Angelica dahurica superfine powder of the present invention

[0039] Preparation method: Take the fresh product of Angelica dahurica, wash it, directly slice or dice it, after drying, crush it into a coarse powder, dry it again to the weight, and pulverize it at 12℃~16℃ for 20 minutes. Minutes and it's ready. Grinding particle size: 300 mesh, 350 mesh, 400 mesh, 500 mesh.

Embodiment 3

[0040] Example 3 Research on Fluidity of Radix Angelicae Radix Superfine Powder of the Present Invention

[0041] The fluidity of micropowder is related to factors such as the force between particles (such as van der Waals force, electrostatic force, etc.), particle size, particle size distribution, particle shape, and surface friction. Some powders are loose and free flowing; others are cohesive. Generally, the particle size of the micropowder is less than 10 μm, which can produce adhesiveness. When the particles smaller than 10 μm are removed or the particles smaller than 10 μm are adsorbed on the larger particles, the fluidity can be improved; The fluidity is not good, it can be dried to improve the fluidity.

[0042] 1. Angle of repose

[0043] The angle of repose is one of the main methods to represent the interaction force between particles. The measurement method generally makes the powder flow down through a funnel and form a cone pile. Let the height of the cone b...

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Abstract

The invention provides a method for preparing angelica dahurica decoction pieces. The method comprises the following steps: (1) grinding a medicinal material such as angelica dahurica into coarse powder; and (2) drying the coarse powder prepared by the step (1), grinding at 12 to 16 DEG C for 20 minutes in a Bailey supermicro pulverizer BFM-100B till a particle size of 300 to 500 meshes. The invention also provides angelica dahurica decoction pieces prepared by the method. The angelica dahurica decoction pieces prepared by the method have the advantages that: after the supermicro medicinal material is ground on a cell level, the surface area is greatly increased, and active ingredients dissolve out quickly; meanwhile, the active ingredients can well contact gastrointestinal mucosa, so theabsorption is easier, the bioactive is retained and medicinal effect is enhanced; and the angelica dahurica super micro powder obtained by the method can ensure good absorption in vivo when the particle size is between 300 and 500 meshes, so the energy consumed in the supermicro grinding process of the angelica dahurica is reduced greatly.

Description

technical field [0001] The invention relates to a method for preparing decoction pieces of Angelica dahurica, in particular to a method for superfinely pulverizing the fresh product of Angelica dahurica. Background technique [0002] Angelica dahurica (Fisch.ex Hoffm.) Benth.et Hook.f. or Hangbaizhi Angelica dahurica (Fisch.ex Hoffm.) Benth.et Hook.f.var.formosana (Boiss.) Shan The dried root of et Yuan has the effects of dispelling wind and dehumidification, opening the orifice to relieve pain, reducing swelling and discharging pus. Modern pharmacological studies have shown that Angelica dahurica has antipyretic and analgesic, anti-inflammatory, anti-pathogenic microorganisms, anti-photosensitivity, cardiovascular regulation, smooth muscle regulation, sedative and hypnotic effects. In addition to being used for medicine, Angelica dahurica is widely used in food, health care products, spices, skin care and cosmetics, daily chemical industry, etc. It is in great demand in do...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/232A61P9/00A61P25/20A61P29/00A61P31/00A61P37/08A61P43/00
Inventor 马逾英蒋桂华张利米小琴郭沛琳杨枝中
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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