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Traumatic injury analgesic cataplasm preparation and preparation method thereof

A technology for bruises analgesic ointment and poultice, applied in the field of medicine, can solve the problems of high irritation, pain, sticking to hair, etc., and achieves the effects of good compatibility and large drug loading in the matrix

Inactive Publication Date: 2010-07-21
GUANGZHOU BAIYUNSHAN PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The original dosage form is a rubber ointment, and the preparation process is simple. After the Chinese medicinal materials are simply crushed into fine powder, mixed with rubber, rosin and other auxiliary materials, and coated on cotton cloth, it is highly irritating. Disadvantages such as pain

Method used

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  • Traumatic injury analgesic cataplasm preparation and preparation method thereof
  • Traumatic injury analgesic cataplasm preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] 【Prescription of medicinal materials】

[0044] 48g ground beetle, 48g raw grass aconite, 48g nux (fried), 48g rhubarb, 48g jiangxiang, 48g double-sided needle, 48g skullcap, 48g cork, 15g knotweed, 24g borneol, 60g camphor, 30g menthol, 30g peppermint oil , methyl salicylate 60g.

[0045] 【Matrix prescription】

[0046] Partially Neutralized Sodium Polyacrylate NP-700 175g Povidone K-90 70g

[0047] Carbomer 980 60g Glycerin 1000g

[0048] Aluminum glycylate 7.5g EDTA-2Na 1.7g

[0049] Micronized silica gel 50g tartaric acid 3g

[0050] Polysorbate-80 50g Purified water Appropriate amount

[0051] Adjusted to 3410g

[0052] Preparation:

[0053] (1) Fourteen medicinal materials in the prescription, take camphor, peppermint oil, borneol, menthol, methyl salicylate, etc., mix and dissolve into an oil, and the oil ① is set aside;

[0054] (2) Take the balsamic and ground beetle and grind them into fine powder, and the medicinal material powder ② for later use;

[00...

Embodiment 2

[0062] [medicine prescription] with embodiment 1

[0063] [substrate prescription] with embodiment 1

[0064] The preparation method is the same as in Example 1, and finally coating, cutting, about 425 pastes, each pastes 70cm 2 .

Embodiment 3

[0066] [medicine prescription] with embodiment 1

[0067] [substrate prescription] with embodiment 1

[0068] The preparation method is the same as in Example 1, and finally coating, cutting, about 230 pastes, each pastes 70cm 2 .

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Abstract

The invention relates to a traumatic injury analgesic cataplasm and a preparation method thereof, the traumatic injury analgesic cataplasm is produced by formula raw materials of traumatic injury analgesic paste according to the process of the cataplasm and comprises a hydrophilic gel matrix, a non-woven fabric back-up material and a traumatic injury analgesic paste drug, and the traumatic injury analgesic paste drug consists of ground beetle, crude kusnezoff monkshood, nux vomica (stir-fried), rhubarb, rosewood heart wood, shinyleaf pricklyash root, baical skullcap root, amur corktree bark, giant knotweed rhizome, borneol, camphor, menthol, peppermint oil and methyl salicylate. The soluble matrix of the cataplasm has good compatibility with water-soluble and fat-soluble drugs, and the drug loading of the matrix is great, thereby being very applicable to medication features of multiple components and large dose of traditional Chinese medicine; compared with an adhesive plaster agent, the cataplasm is easier to soften the horny layer of skin, is conductive to transdermal absorption of the drug and has better air permeability, adhesion to the skin and moisture retention, thereby having the advantages of comfortable use, small irritation to the skin, repeated tearing and pasting, no pollution of clothes, no residue, no pain when tearing after the use and the like.

Description

technical field [0001] The invention relates to a cataplasm preparation, in particular to an analgesic cataplasm preparation for traumatic injuries and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Dieda Analgesic Ointment is a variety produced by Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Baiyunshan Hejigong Pharmaceutical Factory. The dosage form of this product is rubber ointment. It was launched in January 1970. The effect of dampness is used for acute and chronic sprains, chronic lumbago and leg pain, rheumatic joint pain, etc., and its curative effect is well accepted by the majority of patients. The standard of Dieda Analgesic Ointment is included in the "Chinese Pharmacopoeia" 2005 edition, page 631 of the main text. The rubber ointment is made of medicinal material powder. , Two-faced needle, skullcap, cortex, knotweed, borneol, peppermint oil, camphor, methyl salicylate, menthol, etc. The original dos...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/70A61K47/32A61K47/34A61K47/38A61K47/42A61P29/00A61K31/045A61K31/125A61K31/618A61K35/64A61K47/10A61K47/26
Inventor 王建平黄杰伟
Owner GUANGZHOU BAIYUNSHAN PHARM CO LTD
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