Skin firming and lifting compositions and methods of use

A composition and skin technology, applied in skin care preparations, drug combinations, skin diseases, etc., can solve skin inflammation and allergies, prevent bacterial growth, skin aging, etc.

Active Publication Date: 2010-07-14
ACCESS BUSINESS GRP INT LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This barrier prevents the growth of bacteria that can cause skin irritation and irritation, which leads to increased inflammation and contributes to the aging of the skin

Method used

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  • Skin firming and lifting compositions and methods of use
  • Skin firming and lifting compositions and methods of use
  • Skin firming and lifting compositions and methods of use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1: Analysis of extracellular matrix synthesis in vitro.

[0051] Human Hs27 fibroblasts and HEK001 keratinocytes were purchased from ATCC (Manassas, VA). The co-cultures (Co-cultures) were cultured in 24-well plates at a ratio of 1:4 respectively. After the incubation period, the medium was changed and the cells were exposed to test samples (0.1% or 1% v / v) and incubated overnight. The test sample contains: DOT-9002-14A; Satsuma citrus extract; seaweed (Pullulan and / or Nannochloropsisoculata) (eg - TIGHT); Blacktop Algae extract (eg Scopariane); Chlorella extract (eg Dermochlorella); Pea extract; Bamboo extract;

[0052] After overnight incubation with the test samples, supernatants were collected from the cell cultures and analyzed for the presence of α-elastin, procollagen and hyaluronic acid. Elastin was obtained using Fastin from Biocolor, Inc. (Newtownabbey, Northern Ireland) TMElastin Kit to analyze. See Liao J., Vesely I. 2004. "Relationship betwee...

Embodiment 2

[0054] Example 2: Evaluation of skin lifting benefits.

[0055] A three week controlled clinical study was conducted to evaluate the performance and efficacy of the composition of the present invention comprising lifting serum. Specifically, the lifting serum formulations tested in this three week study contained the following ingredients (all percentages reported below are based on the total weight of the composition):

[0056] Medium: water

[0057] Emulsifier: a composition comprising hydrogenated lecithin, sodium methyl stearoyl aurate, glycerin, squalane, hydroxypropylmethylcellulose stearyl ether, and vegetable sorbitan stearate ester

[0058] Skin Conditioners: Caffeine; Dipotassium Glycyrrhizinate; Panthenol; Ethoxydiglycol; Proline; Contains C12-15 Alkyl Benzoate, Dipropylene Glycol Dibenzoate, PPG-15 Stearyl Composition of ether benzoate; caprylic / caprylic triglyceride; di-C12-15 alkyl fumarate; cetyl alcohol; combination comprising polyacrylate 13, polyisobutylen...

Embodiment 3

[0092] Example 3: Irritation, Acnegenicity and Comedogenicity of Skin Firming Products

[0093] A six-week clinical use study was conducted to determine the irritative, comedogenic and comedogenic potential of the skin firming product. Fifty-four female test subjects had self-perceived acne-prone facial skin combined with dry skin, and they completed the study with regular twice-daily use of moisturizer on the face.

[0094] At the baseline visit, subjects were administered in-clinic exaggerated amounts of the test material to the ocular region (approximately 0.5 g). During this study, formulations comprising the compositions of the present invention were applied twice daily to the face and neck of the test subjects for the duration of the study. Clinical evaluations were performed at Baseline, Second Administration of Baseline Visit, Week 3 and Week 6. The inventive formulations measured in this study are disclosed in Example 2.

[0095] As indicated below, at each visit t...

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PUM

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Abstract

Disclosed is a composition comprising a combination of: Polygonum fagopyrum seed extract, Chlorella vulgaris extract, palmitoyl wheat protein hydrolysate, algae extract, and tripeptide. The composition may further comprise one or more of the following: Citrus unshiu peel extract, Sphacelaria scoparia extract, Bambusa vulgaris extract, Pisum sativum (pea) extract, Evodia rutaecarpa fruit extract, and dipalmitoylhydroxy proline. Such compositions are useful in methods for aiding in improving skin firmness, lifting the skin, preventing or decreasing skin sagging, and preventing or decreasing visible signs of aging resulting from internal and external causes such as environmental stresses.

Description

Background technique [0001] A major goal of cosmetic science is to improve the appearance and health of the skin. While visible signs of aging cannot be completely avoided, they can be visibly reduced. Undesirable skin features include wrinkles, fine lines, age spots, uneven skin tone and loss of firmness or sagging of the skin, which are signs of aging skin. Thus, much of the science of cosmetics is aimed at treating underlying conditions that cause or enhance the signs of skin aging. [0002] The underlying conditions that cause signs of skin aging can be characterized as intrinsic and extrinsic. The intrinsic causes of skin aging are inevitable and genetically determined; skin naturally becomes thinner and drier as we age, and important skin proteins, including collagen, maintain skin firmness and maintain skin elasticity The elastin in the skin degenerates, decreases, and cannot be quickly replaced by new skin. External causes of skin aging include exposure to sunlight...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q5/00
CPCA61K36/899A61K36/02A61P17/00A61K8/64A61K2800/59A61K2800/80A61Q19/08A61K8/9789
Inventor A·C·齐默曼D·A·奥图尔
Owner ACCESS BUSINESS GRP INT LLC
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