The invention discloses a computer numerical control machining center based on a quick and automatic tool changing system. The computer numerical control machining center comprises a machine tool body, an automatic tool changing system, a servo driving device and a control system, wherein the automatic tool changing system comprises an automatic tool changing control device, an electric lifting platform, a horizontal rotating base, a disc-type tool magazine, and an installation-height-adjustable manipulator which is used for changing tools; a rotating shaft is arranged below the middle of the installation-height-adjustable manipulator; an installation height adjusting mechanism which is used for adjusting the installation height of the installation-height-adjustable manipulator is arranged on the rotating shaft; the automatic tool changing control device comprises an automatic tool changing controller, a rotation angle detection unit I, a lifting height detection unit, a rotation angle detection unit II, a tool model input unit, an installation height detection unit and a data storage unit. The computer numerical control machining center is reasonable in design, simple and convenient to operate, high in intelligence degree, good in using effect, and shorter in tool changing time. The installation height of the manipulator is adjustable, a control mode is simple, and adjustment of the installation height can be conveniently realized.