The invention provides a fungicide composition and application thereof. Active components of the fungicide composition include meptyldinocap and one or at least two of azoxystrobin, trifloxystrobin, fluoxastrobin, dimoxystrobin, picoxystrobin, metominostrobin, orysastrobin, enestroburin, pyraoxystrobin and SYP-1620, wherein the weight ratio of the two components is (1 to 50)-(50 to 1). The invention further provides the application of the fungicide composition in the prevention and control of plant diseases caused by fungi. The fungicide composition has the beneficial effects that compared with the sterilizing effect of a single component, the sterilizing effect is remarkably improved, an excellent synergistic effect is achieved, the consumption of a medicament is reduced, the pesticide cost of farmers is lowered, and meanwhile, the environmental influence is alleviated; meanwhile, the bactericidal spectrum is expanded, and the generation and development of resistance of the single component can be effectively delayed.