The invention relates to a cyhalofop-butyl-containing weeding composition, which is mainly characterized by comprising 1 to 60 percent of active ingredient A, namely cyhalofop-butyl, 1 to 60 percent of active ingredient B, auxiliary agents and other excipients, wherein the active ingredient B is anilofos, oxaziclomefone or clomazone. The composition can be prepared into wettable powder, water dispersible granules, a suspending agent, suspension emulsion, microemulsion and aqueous emulsion. The weeding composition is used for preventing and controlling annual gramineous weeds in a paddy field.