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41 results about "Viral disorder" patented technology

Viral disorders are a sub set of infectious disorders caused by viruses. Psychologists are interested in this group of diseases for several reasons: They may be prevented by appropriate behavior and psychologists have something to say about how to present warnings and educate people about their choices and to help them adopt safety precautions.

New purine derivatives

The present invention relates to compounds of formula 1 or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or unbranched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, CNS disorders, diabetes, stroke, alopecia or neurodegenerative disorders.
Owner:CANCER RES TECH LTD

New purine derivatives

InactiveUS20060183760A1BiocideNervous disorderArylHalogen
The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or un branched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, CNS disorders, diabetes, stroke, alopecia or neurodegenerative disorders.
Owner:CANCER RES TECH LTD

Purine derivatives

InactiveUS20090270427A1BiocideNervous disorderArylPurine
The present invention relates to compounds of formula 1or pharmaceutically acceptable salts thereof, whereinone of R1 and R2 is methyl, ethyl or isopropyl, and the other is H;R3 and R4 are each independently H, branched or unbranched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H;R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups;R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2.A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, CNS disorders, diabetes, stroke, alopecia or neurodegenerative disorders.
Owner:CANCER RES TECH LTD

Human cDNA clones comprising polynucleotides encoding polypeptides and methods of their use

InactiveUS20060084799A1Diagnostic and prophylactic and therapeutic effectModulating biological activityPeptide/protein ingredientsGenetic material ingredientsFull length cdnaPolynucleotide
The invention provides novel human full-length cDNA clones, novel polynucleotides, related polypeptides, related nucleic acid and polypeptide compositions, and related modulators, such as antibodies and small molecule modulators. The invention also provides methods to make and use these cDNA clones, polynucleotides, polypeptides, related compositions, and modulators. These methods include diagnostic, prophylactic and therapeutic applications. The compositions and methods of the invention are useful in treating proliferative disorders, e.g., cancers, and inflammatory, immune, bacterial, and viral disorders.
Owner:FIVE PRIME THERAPEUTICS

Use of extracts for the treatment of viral disorders

The present invention relates to plant extracts and compositions containing such plant extracts useful in the treatment of viral disorders, including but not limited to the treatment of viral lesions resulting from viruses such as Herpes Simplex virus.
Owner:JOHNSON & JOHNSON CONSUMER COPANIES

A kind of amino-oligosaccharide composition and application thereof

The invention provides an amino-oligosaccharin composition and its preparation method and application. Based on 100% of the total mass of the amino-oligosaccharin composition, it includes the following formula components in mass percentage: hydroxyene adenine 0.0001~ 0.005%, amino oligosaccharin 0.1-1%, organic acid 1-25%, phytonutrient compound 2-15%, solvent 5-30%, surfactant 3-8%, filler 21-89%. The synergistic effect of the amino-oligosaccharin-containing composition of the present invention has a good control effect on plant virus diseases, and has broad-spectrum anti-plant virus properties. Compared with a single agent of amino-oligosaccharin, the control effect on plant virus diseases is improved. 30-100%. The amino oligosaccharin composition has no residue after acting on plants, and is environmentally friendly and safe. The preparation method has simple process, low cost, safety and environmental protection, and is suitable for industrialized production.
Owner:SHENZHEN NOPOSION AGROCHEM

Compositions and methods for treating immune and viral disorders and modulating protein-rna interaction

The present invention relates to methods of treating or decreasing the likelihood of developing a disorder associated with immune misregulation, such as, an autoimmune disorder, or viral or virus-associated disorder in a subject including administering to the subject a composition comprising an activator of a CCCH zinc finger-containing PARP, such as, PARP13 or PARP12. The present invention also relates to methods of treating a TRAIL-resistant disorder, such as, TRAIL-resistant cancer including administering to the subject a composition comprising an activator of a CCCH zinc finger-containing PARP, such as, PARP13 or PARP12. The present invention further relates to methods of modulating a CCCH zinc finger-containing PARP-RNA interaction including contacting a CCCH zinc finger-containing PARP protein or a CCCH zinc finger-containing PARP fusion protein with a CCCH zinc finger-containing PARP activator.
Owner:MASSACHUSETTS INST OF TECH

Purine derivatives

The present invention relates to compounds of formula 1or pharmaceutically acceptable salts thereof, whereinone of R1 and R2 is methyl, ethyl or isopropyl, and the other is H;R3 and R4 are each independently H, branched or unbranched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H;R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups;R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2.A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, stroke, alopecia, CNS disorders, neurodegenerative disorders, or diabetes.
Owner:CANCER RES TECH LTD

NGNA compositions and methods of use

The present invention relates to the field of viral disorders, and in particular to viral obesity. Compositions comprising nutraceutical agents are provided for treating viral obesity. Additionally, compositions comprising nutraceutical agents targeting adenoviruses are provided.
Owner:LIFE SCI NUTRITION AS

NGNA Compositions and Methods of Use

The present invention relates to the field of viral disorders, and in particular to viral obesity. Compositions comprising nutraceutical agents are provided for treating viral obesity. Additionally, compositions comprising nutraceutical agents targeting adenoviruses are provided.
Owner:HYPERTHERMICS HLDG +1

Nanostructures for modulating intercellular communication and uses thereof

Nanostructures, compositions and methods for treating vesicle-related or exosome-related conditions are provided. In some cases, the nanostructures and / or compositions may be used to treat cancers, neurological disorders, rheumatologic disorders, viral disorders or other diseases or conditions at least in part by regulating vesicle uptake. Methods of analyzing, imaging and modulating vesicles and cellular vesicles processes are also provided.
Owner:NORTHWESTERN UNIV

Compounds

The present invention relates to compounds of formula (I)wherein:R1 and R2 are each independently H, alkyl or haloalkyl;R3 and R4 are each independently H, alkyl, haloalkyl or aryl;R5 is alkyl or cycloalkyl or cycloalkyl-alkyl, each of which may be optionally substituted with one or more OH groups;R6 is selected from cyclopropylamino, cyclopropylmethylamino, cyclobutylamino, cyclobutylmethylamino andwhere one of X, Y and Z is N and the remainder are CR9;R7, R8 and each R9 are independently H, alkyl or haloalkyl, wherein at least one of R7,R8 and each R9 is other than H.A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula (I), and the use of said compounds in treating proliferative disorders, viral disorders, stroke, alopecia, CNS disorders, neurodegenerative disorders, or diabetes.
Owner:CYCLACEL +1

Trisubstituted purine derivatives

The present invention relates to compounds of formula (I)wherein:R1 and R2 are each independently H, alkyl or haloalkyl;R3 and R4 are each independently H, alkyl, haloalkyl or aryl;R5 is alkyl or cycloalkyl or cycloalkyl-alkyl, each of which may be optionally substituted with one or more OH groups;R6 is selected from cyclopropylamino, cyclopropylmethylamino, cyclobutylamino, cyclobutylmethylamino andwhere one of X, Y and Z is N and the remainder are CR9;R7, R8 and each R9 are independently H, alkyl or haloalkyl, wherein at least one of R7,R8 and each R9 is other than H.A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula (I), and the use of said compounds in treating proliferative disorders, viral disorders, stroke, alopecia, CNS disorders, neurodegenerative disorders, or diabetes.
Owner:CYCLACEL +1

Use of chalcones for the treatment of viral disorders

The present invention relates to chalcone derivatives and compositions containing such derivatives useful in the treatment of viral disorders, including but not limited to the treatment of viral lesions resulting from viruses such as Herpes Simplex virus.
Owner:JOHNSON & JOHNSON CONSUMER COPANIES

Substituted gemcitabine bicyclic amide analogs and treatment methods using same

In one aspect, the invention relates to substituted gemcitabine aryl amide analogs, derivatives thereof, and related compounds; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating viral disorders and disorders of uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Owner:Z 索

Methods and kits for determining a personalized treatment regimen for a subject suffering from a pathologic disorder

The invention relates to methods and kits for determining and optimizing a personalized treatment regimen for a subject suffering from a pathologic disorder based on calculating the value of M, that indicates the ability of said subject to eliminate said disorder. The invention specifically relates to optimization of interferon treatment of viral disorders.
Owner:YISSUM RES DEV CO OF THE HEBREWUNIVERSITY OF JERUSALEM LTD

A Chinese herbal medicine compound preparation for preventing and treating fish diseases

The invention relates to a traditional Chinese herbal medicine composite preparation for prevention and treatment of fish bacteria and virus diseases. The preparation comprises the following materials: 20-80 percent of copits ash and the balance of astragalus stalks and leaves (the part on the ground). The traditional Chinese herbal materials are mixed proportionally, then are crushed into 5-200 mesh and packaged. According to the addition ratio of 0.1-0.5 percent, the composite preparation is added into fish feed to feed fish for consecutive 3-10 days, as a result, fish bacteria and virus diseases can be effectively prevented; according to the addition ratio of 0.2-1 percent, the product is added into the fish feed to feed the fish for consecutive 1-3 days, and accordingly, the fish bacteria and virus diseases can be effectively treated.
Owner:重庆忠味堂有机食品有限公司

Methods and compositions for treating viral infections

ActiveUS20150072979A1Treating, attenuating or suppressing CMV infectionBiocideOrganic chemistryViral infectionViral replication
The present invention provides compositions and methods for treating, preventing, and inhibiting viral replication, viral infections and viral diseases and disorders, comprising the use of artemisinin derivatives having anti-viral activity.
Owner:THE HONG KONG UNIV OF SCI & TECH +1

Kiaa0779, Splice Variants Thereof, and Methods of Their Use

The invention provides novel polynucleotides, related polypeptides related nucleic acid and polypeptide compositions, and related modulators, such as antibodies and small molecule modulators. The invention also provides methods to make and use these polynucleotides, polypeptides, related compositions, and modulators. These methods include diagnostic, prophylactic, and therapeutic applications. The compositions and methods of the invention are useful in treating proliferative disorders, e.g., cancers, such as kidney and pancreatic cancer; and inflammatory, immune, and viral disorders.
Owner:FIVE PRIME THERAPEUTICS

Nanostructures for modulating intercellular communication and uses thereof

ActiveUS20170087094A1Organic active ingredientsAntibody ingredientsMedicineCellular Vesicle
Nanostructures, compositions and methods for treating vesicle-related or exosome-related conditions are provided. In some cases, the nanostructures and / or compositions may be used to treat cancers, neurological disorders, rheumatologic disorders, viral disorders or other diseases or conditions at least in part by regulating vesicle uptake. Methods of analyzing, imaging and modulating vesicles and cellular vesicles processes are also provided.
Owner:NORTHWESTERN UNIV
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