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71 results about "Monitoring glucose" patented technology
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Integrated receiver for continuous analyte sensor
InactiveUS20080287765A1Simpler and few componentReduce errorsEndoradiosondesCatheterGlucose sensorsData stream
A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.
Owner:DEXCOM INC
Integrated receiver for continuous analyte sensor
InactiveUS20080287764A1Simpler and few componentReduce errorsPharmaceutical delivery mechanismEndoradiosondesGlucose sensorsData stream
A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.
Owner:DEXCOM INC
Integrated receiver for continuous analyte sensor
ActiveUS20080287766A1Simpler and few componentReduce errorsEndoradiosondesCatheterGlucose sensorsData stream
A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.
Owner:DEXCOM INC
Sensor head for use with implantable devices
InactiveUS7471972B2Minimizing negative potential extremesImprove solubilityMicrobiological testing/measurementMaterial analysis by electric/magnetic meansElectrochemical responseAnalyte
The present invention provides a sensor head for use in an implantable device that measures the concentration of an analyte in a biological fluid which includes: a non-conductive body; a working electrode, a reference electrode and a counter electrode, wherein the electrodes pass through the non-conductive body forming an electrochemically reactive surface at one location on the body and forming an electronic connection at another location on the body, further wherein the electrochemically reactive surface of the counter electrode is greater than the surface area of the working electrode; and a multi-region membrane affixed to the nonconductive body and covering the working electrode, reference electrode and counter electrode. In addition, the present invention provides an implantable device including at least one of the sensor heads of the invention and methods of monitoring glucose levels in a host utilizing the implantable device of the invention.
Owner:DEXCOM INC
Method and apparatus for monitoring glucose levels in a biological tissue
ActiveUS7254429B2Convenient amountLow lightDiagnostic recording/measuringSensorsContinuous scanningConcentrations glucose
In accordance with the invention, a low coherence interferometer is used to non-invasively monitor the concentration of glucose in blood by shining a light over a surface area of human or animal tissue, continuously scanning the light over a two dimensional area of the surface, collecting the reflected light from within the tissue and constructively interfering this reflected light with light reflected along a reference path to scan the tissue in depth. Since the reflection spectrum is sensitive to glucose concentration at particular wavelengths, measurement and analysis of the reflected light provides a measure of the level of glucose in the blood. The measurement of glucose is taken from multiple depths within blood-profused tissue, and sensitivity is preferably enhanced by the use of multiple wavelengths. Noise or speckle associated with this technique is minimized by continuously scanning the illuminated tissue in area and depth.
Owner:MASIMO CORP
Membrane for use with implantable devices
The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the implantable device wherein the first domain supports tissue attachment and interferes with barrier cell layer formation and a second domain proximal to the implantable device wherein the second domain is resistant to cellular attachment and is impermeable to cells. In addition, the present invention provides sensors including the biointerface membrane, implantable devices including these sensors or biointerface membranes, and methods of monitoring glucose levels in a host utilizing the analyte detection implantable device of the invention. Other implantable devices which include the biointerface membrane of the present invention, such as devices for cell transplantation, drug delivery devices, and electrical signal delivery or measuring devices are also provided.
Owner:DEXCOM
Membrane for use with implantable devices
ActiveUS20100087724A1Bioreactor/fermenter combinationsBiological substance pretreatmentsAnalyteBiointerface
The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the implantable device wherein the first domain supports tissue attachment and interferes with barrier cell layer formation and a second domain proximal to the implantable device wherein the second domain is resistant to cellular attachment and is impermeable to cells. In addition, the present invention provides sensors including the biointerface membrane, implantable devices including these sensors or biointerface membranes, and methods of monitoring glucose levels in a host utilizing the analyte detection implantable device of the invention. Other implantable devices which include the biointerface membrane of the present invention, such as devices for cell transplantation, drug delivery devices, and electrical signal delivery or measuring devices are also provided.
Owner:DEXCOM INC
Transcutaneous analyte sensor
The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. In some embodiments, a device is provided for monitoring glucose concentration in a host, including a continuous glucose sensor and an integrated receiver including a single point glucose monitor. In some embodiments, a computer system is provided that determines a rate of change of continuous analyte sensor data.
Owner:DEXCOM INC
Analyte sensor
ActiveUS20070027370A1Increase liquid volumeLarge flowMicrobiological testing/measurementCatheterAnalyteBiointerface
Biointerface membranes are provided which can be utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device incorporating such membranes are provided.
Owner:DEXCOM
Method of monitoring glucose level
The method of monitoring or measuring the concentration of glucose level in human and animal blood uses a non-invasive technique and includes measurements of the speed of sound through the blood, the conductivity of the blood, and the heat capacity of the blood, or by non-invasive measurement of any other parameters that can be used to calculate the glucose level. Thereafter, the glucose level for each of the three measurements is calculated and the final glucose value is determined by a weighted average of the three calculated glucose values.
Owner:JMS DIVERSIFIELD HLDG
Analyte sensor
The present invention relates generally to biointerface membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel biointerface membranes, to devices and implantable devices including these membranes, methods for forming the biointerface membranes on or around the implantable devices, and to methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device.
Owner:DEXCOM
Methods of monitoring glucose levels in a subject and uses thereof
Methods of frequently monitoring glucose amounts and / or concentrations in a subject who is at risk for hypoglycemia, hyperglycemia, and / or glucose level fluctuations that put the subject at risk are provided. Also provided are methods of monitoring the effects of one or more pharmaceutical compositions on the levels of glucose in a subject.
Owner:ANIMAS TECH +1
Coherence-gated optical glucose monitor
ActiveUS20050075547A1Reduce volatilitySimplify structure and optical configurationScattering properties measurementsDiagnostics using tomographyMonitor glucoseBlood sugar
This application describes designs, implementations, and techniques for optically monitoring glucose levels of patients without taking blood samples.
Owner:TOMOPHASE
Method and apparatus for monitoring glucose levels in a biological tissue
ActiveUS20080021293A1Convenient amountLow lightDiagnostic recording/measuringSensorsBLOOD FILLEDConcentrations glucose
Owner:MASIMO CORP
Integrated blood sampling analysis system with multi-use sampling module
A simple, miniaturized, disposable acquisition and test module for monitoring glucose or other analytes successively for multiple times is described. The apparatus is designed to collect and test small volumes of blood in a single step. Many samples can be acquired and analyzed using a single disposable sampling module, minimizing the number of disposables and improving ease of use of the system.
Owner:SANOFI AVENTIS DEUT GMBH
Method and apparatus for monitoring glucose levels in a biological tissue
ActiveUS20060063988A1Different scattering propertyReduce noiseDiagnostic recording/measuringSensorsContinuous scanningConcentrations glucose
In accordance with the invention, a low coherence interferometer is used to non-invasively monitor the concentration of glucose in blood by shining a light over a surface area of human or animal tissue, continuously scanning the light over a two dimensional area of the surface, collecting the reflected light from within the tissue and constructively interfering this reflected light with light reflected along a reference path to scan the tissue in depth. Since the reflection spectrum is sensitive to glucose concentration at particular wavelengths, measurement and analysis of the reflected light provides a measure of the level of glucose in the blood. The measurement of glucose is taken from multiple depths within blood-profused tissue, and sensitivity is preferably enhanced by the use of multiple wavelengths. Noise or speckle associated with this technique is minimized by continuously scanning the illuminated tissue in area and depth.
Owner:MASIMO CORP
Personal digital assistant or organizer for monitoring glucose levels
ActiveUS20190216319A1Evaluation of blood vesselsMedical automated diagnosisAddress bookMonitor glucose
The present disclosure provides an electronic device that includes at least one sensor indicative of a physiological condition of a user, the at least one sensor worn by a patient. The electronic device can further include a location determination module configured to determine a location of a patient. The electronic device can receive a measured information from the sensor and determine if the physiological condition of the user indicates an urgent medical need. When the physiological condition of the user indicates an urgent medical need, the electronic device can contact emergency services and access and contact one or more of a contact in an electronic address book associated with the processing system. The electronic device can provide a location of the user based on information determined by the location determination module.
Owner:CERCACOR LAB INC
Methods of monitoring glucose levels in a subject and uses thereof
Methods of frequently monitoring glucose amounts and / or concentrations in a subject who is at risk for hypoglycemia, hyperglycemia, and / or glucose level fluctuations that put the subject at risk are provided. Also provided are methods of monitoring the effects of one or more pharmaceutical compositions on the levels of glucose in a subject.
Owner:ANIMAS TECH
Method and implantable system for blood-glucose concentration monitoring using parallel methodologies
ActiveUS20100280348A1Reliable calculationMeasuring blood-glucose concentration reliably and accuratelyElectrocardiographyCatheterConcentrations glucoseMonitor glucose
In an implantable medical device for monitoring glucose concentration in the blood, a blood-glucose concentration analysis is performed using correlations of blood-glucose concentration with measures of metabolic oxygen consumption including oxymetric, and / or temperature. Analysis of electrocardiographic data is used in a parallel method to detect and / or confirm the onset and / or existence and / or extent of hypoglycemia and / or hyperglycemia. Blood-glucose concentration calculation is enhanced by using the combination of the oxygen metabolism analysis and electrocardiographic analysis.
Owner:PACESETTER INC
Nanofibers with high enzyme loading for highly sensitive biosensors
ActiveUS20110229916A1High areaIncrease flexibilityBioreactor/fermenter combinationsBiological substance pretreatmentsFiberEnzyme system
The invention provides high enzyme loading nanofibers and processes utilized in their fabrication, the nanofibers suitable for use as a new class of highly sensitive and stable biosensors capable of monitoring glucose at low levels. The biosensors, comprising nanofiber enzyme materials fabricated from organic solvent-based polymer-enzyme systems, can be used effectively in non-invasive transdermal biosensing applications.
Owner:THE UNIVERSITY OF AKRON
SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
ActiveUS20070110672A1Detailed informationHigh sensitivityUltrasonic/sonic/infrasonic diagnosticsChemiluminescene/bioluminescenceMetaboliteBoronic acid
Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.
Owner:CERCACOR LAB INC
Glucose measurement utilizing non-invasive assessment methods
InactiveUS7039447B2Withdrawing sample devicesPhase-affecting property measurementsAnalyteSkin surface
This involves non-invasive glucose measurement processes for determining blood glucose level in the human body. After achieving a static level of glucose at a surface of the skin over some period of time, the glucose may then be measured by a variety of different processes. A sample of the glucose may also first be extracted from the skin and this sample may then be measured. Clearly, these processes are especially suitable for monitoring glucose levels in the human body, and is especially beneficial to users having diabetes mellitus. These procedures may be used for other analyte materials that are found in appropriate regions of the outer skin.
Owner:VIVOMEDICAL INC
Glucose Monitor and Method of Use Thereof
InactiveUS20090156915A1Avoid inconvenienceReduce riskDiagnostic recording/measuringSensorsSteering wheelDriver/operator
An apparatus for monitoring glucose comprising a processor, an indicating mechanism and sensors that are disposed proximate the skin of a person when the skin is in contact with a motor vehicle operational component such as the steering wheel. The apparatus for monitoring glucose measures the driver's glucose concentration via optical coherence tomography or other non-invasive technique, analyzes the driver's glucose concentration via the processor and displays the driver's glucose concentration via the indicator, or alternately sends an alarm signal. The method for monitoring glucose further comprises programming the processor with a range of glucose concentrations, comparing the driver's glucose concentration with the range and signaling an alert if the driver's glucose concentration is outside the range.
Owner:CROSS BILL
Optical sensor configuration and methods for monitoring glucose activity in interstitial fluid
InactiveUS20120053427A1Accurate measurementPrevent flexing of the sensorCatheterDiagnostic recording/measuringBlood Glucose MeasurementMonitor glucose
Embodiments of the invention are directed to an optical sensor for detecting blood glucose by deploying the optical sensor into the interstitial fluid. The sensor comprises a chemical indicator system capable of generating an optical signal related to the blood glucose activity. The sensor further comprises a means for generating and detecting an optical reference signal unrelated to the blood glucose activity, such that ratiometric correction of blood glucose measurements for artifacts in the optical system is enabled.
Owner:MEDTRONIC MIMIMED INC
Optical non-invasive blood monitoring system and method
ActiveUS20090043178A1Simple designLeveling precisionDiagnostic recording/measuringSensorsExtra cellular fluidRefractive index
A simple noninvasive technique that is capable of very accurate and fast blood analyte, e.g., glucose, level monitoring is provided. Fluctuation in the levels of glucose and other analytes affect the refractive index of blood and extra cellular fluid in biological tissue. Given that the propagation speed of light through a medium depends on its refractive index, continuous monitoring of analyte levels in tissue is achieved by measuring characteristics of the tissue that can be correlated to the refractive index of the tissue. For instance, the frequency or number of optical pulse circulations that are transmitted through an individual's tissue of known thickness within a certain time period can be correlated to an individual's blood glucose level.
Owner:BELOTSERKOVSKY EDWARD
Single detector infrared ATR glucose measurement system
InactiveUS20050137469A1Sufficient pressureDiagnostic recording/measuringSensorsHuman bodyGlucose Measurement
A single detector infrared ATR glucose measurement system is disclosed herein. The device uses attenuated total reflection infrared spectroscopy. Preferably, the device is used on a fingertip and compares two specific regions of a measured infrared spectrum to determine the blood glucose level of the user. A single IR detector is utilized along with an alternating filter. This device is especially suitable for monitoring glucose levels in the human body, and is especially beneficial to users having diabetes mellitus. The device and procedure may be used for other analyte materials which exhibit unique mid-IR signatures of the type described herein and that are found in appropriate regions of the outer skin.
Owner:MEDOPTIX
Method and apparatus for non-invasively monitoring concentrations of glucose or other target substances
InactiveUS20050272990A1Improve accuracyImprove reliabilityAnalysing fluids using sonic/ultrasonic/infrasonic wavesAnalysing solids using sonic/ultrasonic/infrasonic wavesMedicineAcoustic wave
A method and apparatus for non-invasively measuring concentration of a target substance such as glucose within a body by: activating a pulse source to apply to the body a series of pulses of energy highly absorbable by the target substance to generate, by the photoacoustic effect, a series of acoustic waves propagated through an acoustic channel in the body; detecting the acoustic waves to produce an electrical signal having a frequency corresponding to the frequency of the acoustic waves generated by the photoacoustic effect; controlling the pulse source to change the frequency at which the energy pulses are applied to the body such that the detector detects a whole integer number of wavelengths in the acoustic channel irrespective of variations in the target substance concentration within the body; and utilizing a measurement of the frequency, or change in frequency, of the pulses to produce a measurement of the concentration, or change in concentration, of the target substance.
Owner:NEXENSE
Systems and methods for implementing rapid response monitoring of blood concentration of a metabolite
Systems and methods for monitoring the concentration of glucose or other metabolites by way of a low-volume microdialysis-probe (10) operative in accordance with a pulsed mode of flow through a flow path (12) defined by a layered structure. Also described are a system and a method for deployment of the microdialysis probe (10) within the body and a technique for deriving a metabolite concentration of the basis of a rate of change of an optical parameter.
Owner:G SENSE LTD
Glucose measurement utilizing non-invasive assessment methods
InactiveUS20030105391A1Withdrawing sample devicesPhase-affecting property measurementsAnalyteSkin surface
This involves non-invasive glucose measurement processes for determining blood glucose level in the human body. After achieving a static level of glucose at a surface of the skin over some period of time, the glucose may then be measured by a variety of different processes. A sample of the glucose may also first be extracted from the skin and this sample may then be measured. Clearly, these processes are especially suitable for monitoring glucose levels in the human body, and is especially beneficial to users having diabetes mellitus. These procedures may be used for other analyte materials that are found in appropriate regions of the outer skin.
Owner:VIVOMEDICAL INC
Microneedles and method of manufacture
A microneedle device (200) including at least one microneedle (1) having one or more nanowires (203) on a surface of said at least one microneedle. The microneedle device is typically used in a sensor such as a sensor for monitoring glucose levels in the body and the nanowires may have a membrane (207) covering at least part of the nanowires.
Owner:SWANSEA UNIV
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