A compression stocking, a weaving process of the compression stocking, and a seamless hosiery machine applied in the process. A stocking body (2) of the compression stocking comprises a stable region (11), compression gradually-changing regions (12, 13, 14), and a compression difference region. The stable region (11) is connected to a stocking foot (3). A length parameter (LA) and a middle girth parameter (B) of the stable region (11) are set separately according to a length parameter (LA) of an ankle and a girth parameter (cB) of a thinnest part of the ankle. The interface compression in the stable region (11) is kept consistent. The compression gradually-changing regions (12, 13, 14) are located between the stable region (11) and a welt (1), the stable region (11), the compression gradually changing regions (12, 13, 14) and the welt (1) are sequentially connected from bottom to top. The interface compression in each of the compression gradually-changing regions (12, 13, 14) gradually decreases from bottom to top, the interface compression of the joint of the neighboring compression gradually-changing regions (12, 13, 14) is kept successive, and each of the compression gradually-changing regions (12, 13, 14) has a preset compression gradually-decreasing gradient. The compression difference region is located in a local region surrounded by the stable region (11) and / or the compression gradually-changing regions (12, 13, 14). The interface compression in the compression difference region may be distributed in a gradient manner or in an even manner. The compression stocking can meet requirements for the specific compression magnitude and the distribution of different parts of a lower limb.