70 results about "Aneurysm treatment" patented technology

A stent for application within an aneurysm the stent comprising an elongated tubular member having a proximal end and a distal end. The stent has a proximal portion expandable from a first diameter to a second diameter. The distal end of the stent may be expandable to a third diameter, which third diameter is larger than the second diameter. The stent may be left disposed across the neck of the aneurysm.

Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm treatment and / or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.

An self-expanding frame is mounted on the distal end of a shaft. The frame is sized and configured so that it can be inserted into the cavity of an aneurysm. Suction is applied to the interior of the aneurysm through the shaft or through another catheter, and the wall of the aneurysm is collapsed onto the exterior surface of the frame. The frame is then collapsed upon further suction being applied to the interior of the aneurysm, which collapses the aneurysm wall with it. The frame folds down on itself, carrying with it the aneurysm wall. The frame is detachable from the shaft and can be left in the collapsed aneurysm.

The present invention is directed to an intravascular treatment for intracranial aneurysms. The invention consists of a patch stent and, also, a patch stent delivery system allowing one to rotate the stent to align the patch with the neck of the aneurysm. A self-expanding nitinol framework holds the patch in place, a radiopaque agent allows the patch location to be visualized and a pusher tube that is mechanically locked into the unexpanded stent is used to push the stent out of the catheter with rotational and longitudinal control necessary to align the patch with the aneurysm. A self-expanding framework is used to support a patch at the neck of the aneurysm. The patch is designed to reduce the blood circulation in the aneurysm and the stagnant blood will clot or thrombus. The thrombus will stop any current blood leakage into the brain and will dramatically reduce the possibility of future leaks or potentially deadly ruptures. Over time the thrombus will be absorbed and the volume of the aneurysm will shrink reducing pressure on surrounding tissue.

Devices for treating aneurysms are disclosed. The devices are adapted and configured to modify blood flow at the aneurysm. More specifically, the invention discloses devices for treating cerebral aneurysms using devices adapted and configured to be delivered to a blood vessel in the brain on a distal tip of a microcatheter. The aneurysm devices comprise: a device adapted to be delivered to a blood vessel aneurysm on a distal tip of a catheter and further adapted to modify blood flow at the aneurysm.

The present invention is directed to aneurysm treatment devices which are capable of being delivered to the situs of a vascular aneurysm through a catheter. The treatment devices comprise, in general, an expandable stent having fenestrations and a reactive material selectively applied to not all of the fenestrations. The reactive material has a non-reacted state and a reacted state and the reactive material in the reacted state is capable of increasing the resistance to blood flow through said fenestrations.

Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm treatment and / or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.

An aneurysm treatment device for in situ treatment of aneurysms comprises a collapsible member having a first shape wherein the first shape is an expanded geometric configuration, and a second shape, wherein the second shape is a collapsed configuration that is loadable into a catheter. The aneurysm treatment device is capable or returning to the first shape in the sac of an aneurysm upon deployment, where it occludes the aneurysm. In another embodiment an occlusion device comprises a flexible, longitudinally extending elastomeric matrix member that assumes a non-linear shape to conformally fill a targeted vascular site.

An aneurysm treatment device for in situ treatment of aneurysms comprises a collapsible member having a first shape wherein the first shape is an expanded geometric configuration, and a second shape, wherein the second shape is a collapsed configuration that is loadable into a catheter. The aneurysm treatment device is capable of returning to the first shape in the sac of an aneurysm upon deployment, where it occludes the aneurysm.

The invention is directed to an apparatus, such as a medical device, having a surface coated or covered with a decellularized extracellular matrix or having a component comprising the decellularized extracellular matrix for implantation into a subject, preferably a human. In one embodiment of the invention, a decellularized extracellular matrix is used to form a bodily implant such as a vein, an artery, an esophagus, or a ventricular restraining device. In some embodiments of the invention, the decellularized extracellular matrix is configured to be a time released therapeutic. In another embodiment of the invention, a decellularized extracellular matrix forms an aneurysm treatment device, such as an aneurysm coil, a seal, a pouch, or a filler. In a further embodiment of the invention, decellularized extracellular matrix is used to embolize lesions, tumors, or vessels. Methods for making the tissue regeneration scaffold and methods for manufacturing a coated or covered medical device having a component comprising decellularized extracellular matrix of body tissues are also provided.

Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm treatment and / or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.

An endoluminal aneurysm treatment system of an expandable bypass prosthesis and an extension prosthesis with a flared distal portion which, upon expansion, frictionally engages the proximal end of the bypass prosthesis.

The present invention is directed to aneurysm treatment devices which are capable of being delivered to the situs of a vascular aneurysm through a catheter. The treatment devices comprise, in general, a body member formed by at least one support member and a reactive material selectively applied to the at least one support member. The body member provide support mechanical support to a weakened or otherwise incompetent blood vessel. The reactive material is capable of restricting or occluding blood flow to the aneurysm, without substantially affecting blood flow through the blood vessel.

Aneurysms are treated by placing a scaffold across an aneurysmal sac to provide a blood flow lumen therethrough. An aneurysmal space surrounding the scaffold is filled with one or more expandable structures which are simultaneously or sequentially expanded to fill the aneurysmal space and reduce the risk of endoluminal leaks and scaffold migration. The expandable structures are typically inflatable and delivered by delivery catheter, optionally with an inflation tube or structure attached to the expandable structure.

Disclosed are coating compositions, processes, and designs for endowing vascular devices with thromboresistant and endothelializing properties. Also disclosed are designs of vascular devices used as aneurysm treating devices for assisting in the delivery, packing, and maintenance of embolization coils within an aneurysm, particularly a neurovascular aneurysm.

A device for occluding an aneurysm comprising: a detachable, semi-compliant, radially-expanding balloon mounted on a catheter, wherein the balloon is in fluid communication with the catheter, wherein the balloon comprises a plurality of micropores, and wherein the micropores in the balloon allow expression of a bio-adhesive fluid at a defined pressure from the inside to the outside of the balloon.

A stent device for introduction into a bifurcation aneurysm, comprising a radially expandable elongated wire mesh tube having a proximal end and a distal end. The distal end is expandable into a cone shaped portion of a larger diameter than the proximal end. A web of material is arranged across said distal end of said stent device for sealing an aneurysm at a neck portion thereof.

Disclosed is an implantable graft assembly comprising a graft secured to a expandable tubular frame, the graft only partially covering the frame and the use of the graft assembly in treating an aneurysm, especially a cerebral aneurysm. Disclosed is also a method of treating an aneurysm by deploying an implantable graft assembly. Disclosed is also the use of serous tissue for the preparation of a cerebrovascular implant, especially as a graft, especially as a component of a cerebrovascular implantable graft assembly.

Aneurysm treatment apparatus includes a steerable catheter assembly having a catheter with a steerable distal end. A pouch is disposed over the distal end of the catheter so as to be in co-axial overlying relationship therewith. A constraining sheath is disposed over a major portion of the pouch and has a proximal sheath portion which is bonded to the catheter. The sheath terminates short of the distal end of the catheter, so as to leave a distal end of the pouch exposed. The steerable catheter can be steered into an aneurysm sac and filler material fed through the catheter in order to fill chamber of the pouch. The pouch will expand from its distal end with filler material and gradually slide off the sheath as it fills the aneurysm sac. The sheath prevents the pouch from expanding proximally, and potentially adversely affecting the filling process.

An external aneurysm support scaffold is implanted around an exterior surface of an aneurysm and prevents substantial dilation or progression of the AAA. Minimally invasive delivery is used via port-access, i.e. for aortic aneurysms along the back, abdomen, or thorax, to a location externally adjacent the aneurysm, such as via laparascopic delivery. The scaffold is unwound or unfolded in-situ to extend partially (e.g. about 270 degrees) or completely circumferentially around the aneurysm. Unique delivery devices allow for deployment around the aneurysm. Gaps between an array of transverse fingers of the scaffold may accommodate branch vessels extending from the aneurismal vessel, such as aortic perforators. An agent is injected to treat an aneurysm, such as by providing support, cell retention or recruitment, and / or angiogenesis. Living cells are delivered to treat an aneurysm. An adjustable graft polymerizes in-situ to support an aneurysm conformed therewith.

An occlusion system, method, and apparatus which treats an aneurysm in a primary vessel such as an intracranial vessel. Aneurysm types treatable by means of this invention include bulge (sometimes referred to as a true aneurysm), dissecting aneurysms in which the layers of vessel wall are partially delaminated, and what are referred to a “false” aneurysm defined by a relatively small opening in the parent vessel wall fluridically coupled to a bulb-shaped sac, also defined by the vessel wall. The system includes an occlusion device configured for deployment in the parent vessel that restricts fluid flow to the aneurysm. A patch on the device covers the neck of the aneurysm. The system includes a marker in a defined relationship with the patch, which allows for axial and rotational positioning of the device.

Devices and methods for treating aneurysms are disclosed. The devices are adapted and configured to modify blood flow at the aneurysm. More specifically, the invention discloses devices and methods for treating cerebral aneurysms using devices adapted and configured to be delivered to a blood vessel in the brain on a distal tip of a microcatheter. The aneurysm devices comprise: a device adapted to be delivered to a blood vessel aneurysm on a distal tip of a catheter and further adapted to modify blood flow at the aneurysm.

An aneurysm treatment device for in situ treatment of aneurysms comprises a collapsible member having a first shape wherein the first shape is an expanded geometric configuration, and a second shape, wherein the second shape is a collapsed configuration that is loadable into a catheter. The aneurysm treatment device is capable or returning to the first shape in the sac of an aneurysm upon deployment, where it occludes the aneurysm. In another embodiment an occlusion device comprises a flexible, longitudinally extending elastomeric matrix member that assumes a non-linear shape to conformally fill a targeted vascular site.

Implants and methods used for the treatment of aneurysms are disclosed. More particularly, embodiments of an implant having a modular pattern are disclosed for the treatment of cerebral aneurysms to prevent intracranial hemorrhage and aneurysm rupture.

The present invention relates to an endoprosthesis having a plurality of web rings, pairs of which are coupled in one or more points by foot extensions protruding from at least one of the web rings. The endoprosthesis of the present invention provides a high level of flexibility and an elevated degree of scaffolding to a body lumen, and may be configured as a stent, graft, valve, occlusive device, trocar or aneurysm treatment device usable in a variety of intralumenal applications for treating vascular, coronary, biliary, esophageal, renal, urological and gastrointestinal conditions.

It is an object of the present invention to provide a polymer material, the histocompatibility of which has been improved by irradiation of ion beam, which prevents an aneurysm having a risk of rupture from actually rupturing. The present invention provides a material for treating aneurysms, which is composed of a polymer material containing carbon as a constitutional element, and which is produced by modifying at least a portion of the surface thereof by ion bombardment.

The present invention is an aneurysm treatment device for treating aneurysms of various shapes and sizes.

The present invention relates to covered endoprosthetic devices. Covered endoprosthetic devices comprise an endoprosthesis and a sheath. The sheath comprises a central portion and outer portions, wherein the central portion preferentially restricts or causes a restriction of blood flow. Blood flow can be reduced by the central portion of the sheath by varying the permeability of the sheath or by having projections on the sheath that slow blood flow. Permeability may be provided by perforations or holes in the material of the sheath or by varying the polymer structure that makes up the sheath itself. The outer portions of the sheath do not substantially reduce blood flow. Methods of using sheath-covered endoprosthetic devices of the invention to treat aneurysms, especially aneurysms in proximity to small perforator vessels or arteries, are also encompassed.

An irritant or polymer is dispensed to the inner surface area of an aneurysm to exert a contractile force on the inner surface area of the aneurysm, thereby shrinking the aneurysm. As a result, the artery wall at the aneurysm site is strengthened, the risk of rupture is decreased, and at least a partial cure for the expansion of the arterial wall at the aneurysm site is provided.