Effervescence tablet for treating colpitis, preparation method and use thereof
An effervescent tablet and vaginitis technology, applied in the field of external effervescent tablets, can solve the problems of affecting the curative effect, bacteria easily forming drug resistance, toxic and side effects, etc., and achieve the effects of improving the therapeutic effect, protecting the self-cleaning ability of the genitals, and facilitating medication
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Embodiment 1
[0155] Coptidis 50g Nuxseed 20g Smilax 200g
[0156] Curcuma 140g Gallat 170g Pomegranate peel 140g
[0157] β-cyclodextrin 40g Sodium bicarbonate 150g Polyethylene glycol 50g
[0158] Citric acid 300g Magnesium stearate 10g Lactose 50g
[0159] Sodium carboxymethyl starch 200g
[0160] a. Crush 140 g of the raw material curcuma zedoary into a coarse powder, add 5 times the amount of water, extract the volatile oil for 0.3 hours, carry out inclusion inclusion of the volatile oil with 5 g of β-cyclodextrin, keep the temperature at 15°C, stir for 0.1 hour, suction filter, and dry for 0.2 hour, Grind finely, pass through a 20-mesh sieve, and set aside;
[0161] b. Crushing 50 g of Coptidis rhizome and 20 g of Nuxychnium chinensis into coarse powder, adding 3 times the amount of 30% ethanol to reflux extraction once for 0.1 hour, combining the filtrates, concentrating under reduced pressure to obtain extract, and set aside;
[0162] c. Combine 200 g of the raw material Smilax ...
Embodiment 2
[0167]a. Crush 250g of the raw material curcuma curcuma into coarse powder, add 8 times the amount of water, extract the volatile oil for 3 hours, carry out inclusion inclusion of the volatile oil with 20g of β-cyclodextrin, keep the temperature at 20°C, stir for 1.0 hour, filter with suction, dry and finely grind , through a 60-mesh sieve, and set aside;
[0168] b. Grinding 200 g of Coptidis Rhizome and 80 g of Nuxychnium Chinensis into coarse powder, adding 8 times the amount of 50% ethanol to reflux extraction twice, each time for 1.5 hours, combining the filtrates, concentrating under reduced pressure to an extract, and set aside;
[0169] c. Combine 350g of the raw material sarsaparilla, 260g of gall, 250g of pomegranate peel and the dregs extracted from steps a and b, add 8 times the amount of water and decoct twice for 1 hour each time, combine the filtrate, concentrate under reduced pressure, and set aside ;
[0170] d, combine step c and step b extract, mix well, sp...
Embodiment 3
[0174] a. Crush 360g of the raw material Curcuma curcuma into coarse powder, add 10 times the amount of water, extract the volatile oil for 10 hours, carry out inclusion inclusion of the volatile oil with 200g of β-cyclodextrin, keep the temperature at 25°C, stir for 2.5 hours, filter with suction, dry, and grind finely , passed through a 100-mesh sieve, and set aside;
[0175] b. Crushing 300 g of Coptidis rhizome and 100 g of Nuxychnium chinensis into coarse powder, adding 10 times the amount of 85% ethanol to reflux extraction for 3 times, each time for 2.5 hours, combining the filtrates, concentrating under reduced pressure to an extract, and set aside;
[0176] c. Combine 450g of raw materials Smilax smilax, 430g of gall, 460g of pomegranate peel with the dregs extracted from steps a and b, add 15 times the amount of water to decoct 3 times, each time for 2.5 hours, combine the filtrate, concentrate under reduced pressure, and set aside ;
[0177] d, combine step c and s...
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