Basis-reinforcing eyesight-improving dropping pill for treating eye disease and its preparing method

A Mingmu Dropping Pill and an unknown technology are applied to the Guben Mingmu Dropping Pill for treating eye diseases and the field of preparation thereof, which can solve the problems of unfavorable improvement of patients' ability to seek medical treatment, low dissolution rate, and low drug content, and achieve improved bioavailability. effect of rapid dissolution and absorption, high degree of automation

Inactive Publication Date: 2005-12-21
重庆健能医药开发有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
The drug content of granules is also low, and it is inconvenient to take
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0032] The preparation method of Guben Mingmu Dropping Pills of the present invention will be further described with several groups of specific examples.

[0033] [Group 1: Trials with a single substrate]

[0034] 1. Raw materials: According to [Appendix], the dry powder of the mixture containing active pharmaceutical ingredients of safflower, myrobalan, safflower, clove, borneol, and bear bile powder is prepared for use;

[0035] 2. Matrix: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Polyoxyl 40 Stearate, Beta Cyclodextrin, Poloxamer, Sodium Carboxymethyl Starch, Sodium Lauryl Sulfate, Span 40, Tween 80, Stearic Acid, Sodium Stearate , glycerin gelatin, shellac;

[0036] 3. Proportion: take g or kg as the unit, by weight parts, mixed drug raw material: matrix = 1:1~1:9;

[0037] 4. Prepare Guben Mingmu Dropping Pills with different specifications according to the process given ...

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Abstract

The present invention discloses a Chinese medicine composition with the function of improving acuity of vision for curing the diseases of dim vision and red-dry eyes. Said Chinese medicine composition can be made into the oral preparation Guben Mingmu dripping pills, and is made up by using mixture containing active components of 6 Chinese medicinal materials of carthamus flower, chebule, corydalis impatiens, clove, borneol and bear's gall powder as raw material and medicinal carrier as matrix through a certain preparation process.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has the functions of regulating gaseous ulcer and improving eyesight, and is used for the treatment of diseases such as blurred vision, conjunctival congestion and dryness caused by gastroentery, especially relates to a medicinal composition containing safflower, myrobalan chebula, Violet chinensis, and cloves. An oral preparation of a pharmaceutical composition prepared from a mixture of active ingredients of six traditional Chinese medicines, borneol, bear bile powder, etc., as raw materials. Background technique [0002] According to the preparation method given in the national drug standard WS-10485 (ZD-0485)-2002, Guben Mingmu Granules is a kind of granule with the function of regulating collapse gas and improving eyesight, and is used for vision caused by collapse gas. Oral granules for the treatment of unknown, red and dry eyes and other diseases have been clinically verified a...

Claims

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Application Information

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IPC IPC(8): A61K35/413
Inventor 曲韵智
Owner 重庆健能医药开发有限公司
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