Ginseng and fleece-flower root dripping pill and its preparing method

A technology of ginseng and Polygonum multiflorum, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, can solve problems such as adverse overall health level, inconvenient taking or carrying, and low dissolution rate, and is conducive to labor protection. and environmental protection, improved bioavailability, accelerated dissolution and absorption

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, the oral liquid also has the disadvantages of low drug content, difficulty in taking and measuring, inconvenient taking or carrying, etc.
[0007] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of the ginseng-shouwu dripping pills of the present invention will be further described.

[0029] Group 1: Tests with a single matrix

[0030] 1. Preparation of the drug extract: Prepare according to the preparation method 1, and obtain the dry extract powder containing the active ingredients of two traditional Chinese medicines such as red ginseng and Polygonum multiflorum for subsequent use;

[0031] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0032] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0033] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Ginseng Shouwu Dripping Pills with different specifications.

[0034] [test results]

[0...

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PUM

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Abstract

The ginseng-fleeceflower root dripping pill has the functions of invigorating liver and kidney and benefiting vital energy and blood, and is used in treating lacking of essence and blood, prematurely grey hair and beard, neurosism, amnesia, insomnia, etc. The ginseng-fleeceflower root dripping pill is prepared with red ginseng and fleeceflower root as main material, and through extracting active components and further preparation with matrix carrier, and has high bioavailability, fast acting, high effective content, high active component content and low cost.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the functions of invigorating liver and kidney, nourishing qi and blood, and is used for treating weak qi and blood, premature graying of beard and hair, neurasthenia, forgetfulness, insomnia, loss of appetite, and excessive fatigue. A pharmaceutical composition oral preparation prepared from two traditional Chinese medicines such as Radix Polygoni Multiflori as raw materials. Background technique [0002] According to the ministerial drug standard WS 3 -Ginseng Shouwu Jing prepared by the preparation method given in B-0176-90 is a kind of liver and kidney, nourishing qi and blood effects, used for the treatment of weak qi and blood, premature graying of beard and hair, neurasthenia, forgetfulness and insomnia , oral liquid for poor appetite, fatigue and other diseases, has been clinically verified and has definite curative effect. It is a commonly used drug for clinical and fa...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P1/14A61P25/20A61P43/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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