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Dripping pills for reducing swelling and easing pain and its preparing method

A dripping pill and rheumatism technology, applied in non-central analgesics, medical preparations containing active ingredients, pill delivery, etc., can solve the problems that are not conducive to improving the ability of patients to seek medical treatment, unfavorable overall health level, and physical hazards of staff , to avoid the first-pass effect, improve bioavailability, and avoid gastrointestinal irritation symptoms

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0042] Now with several groups of specific examples, the preparation method of Zhengqing Fengtongning dripping pills of the present invention will be further described.

[0043] Group 1: Tests with a single matrix

[0044] 1. Drug raw material: sinomenine hydrochloride;

[0045] 2. Matrix: polyethylene glycol (2000、4000、6000、8000、10000、20000), polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0046] 3. Proportion——with g or kg as the unit, by weight parts, sinomenine hydrochloride: substrate=1:1~1:9;

[0047] 4. Then prepare according to the process of [Preparation Method] 4-7, that is, Zhengqing Fengtongning dripping pills of various specifications can be prepared.

[0048] [test results]

[0049] Test 1: In order to observe the difference in quality of Zhengqing Fengtongning dripping pills prepared when the dry powder of the drug...

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Abstract

The invention discloses a medicinal composition which has the actions of dispersing pathogenic wind and dehumidifying, promoting blood circulation, relieving pain, treating knuckle ache, rheumatism and chronic infectious arthritis. The composition has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, and less toxic and side effects. The drop pill is prepared by employing the process for preparing traditional Chinese medicinal injections.

Description

technical field [0001] The invention relates to a medicine with the functions of expelling wind and dehumidification, promoting blood circulation and dredging collaterals, clearing swelling and relieving pain, and is used for treating wind-cold-damp arthralgia syndrome, such as muscle soreness, joint swelling, pain, difficulty in flexion and extension, numbness and stiffness, and rheumatism and rheumatoid arthritis. The pharmaceutical composition for those with the above-mentioned syndromes, in particular relates to an oral preparation based on the prescription of Fangzheng Qingfengtongning Injection, a traditional Chinese medicine, which is reformed in dosage form. Background technique [0002] Zhengqing Fengtongning Injection, which is prepared according to the formula and preparation process given in the drug standard WS3-B-3171-98, is used for the treatment of wind-cold-damp arthralgia, symptoms such as muscle aches, joint swelling, pain, The traditional Chinese medicine...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K31/4748A61P19/02A61P21/00A61P29/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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