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Glossy ganoderma preparation containing main active substance of glossy ganoderma herb and preparing method thereof

An active substance, Ganoderma lucidum technology, applied in the field of Ganoderma lucidum preparations and preparations rich in the main active substances of Ganoderma lucidum whole herb, can solve the problems of low extraction rate of active ingredients, destruction of active ingredients, loss, etc., to improve health care value and ensure full absorption , the effect of promoting development

Inactive Publication Date: 2005-06-22
SHENYANG KESI TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there is a significant difference in the polysaccharide content of these two products, most of the polysaccharides still maintain a molecular weight of hundreds of thousands, and it is still difficult for middle-aged and elderly people to fully absorb them
[0019] 2) Efficient and non-destructive extraction of active ingredients
[0020] The extraction technology based on the traditional heating principle, whether it is water extraction, alcohol extraction, or alcohol-water co-extraction, has not broken through the decoction category of traditional Chinese medicine in essence. Problems such as damage and loss; microwave extraction technology can solve the problems of traditional heating extraction technology in principle, but there are still breakthroughs in industrialized device technology and how to avoid a large amount of ineffective components. Supercritical extraction can realize effective extraction of small molecules. High-purity extraction of ingredients, but not suitable for extraction of macromolecular active ingredients such as Ganoderma lucidum polysaccharides
[0021] In short, the existing processing technology is still difficult to achieve "high quality and low price" of Ganoderma lucidum preparations, and technological breakthroughs are urgently needed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The ganoderma preparation rich in ganoderma spore powder and ganoderma fruiting body main active substances is prepared as follows:

[0043] 1) Microwave softening treatment of Ganoderma lucidum spore powder:

[0044] ①2kg Ganoderma lucidum spore powder is placed in a resonant microwave cavity;

[0045] ② Take 2.8L of anhydrous acetic acid and add 1.2L of water to make 4L of acetic acid solution;

[0046] ③Take 4L of the above solution, add it to the above microwave cavity, stir well to make it evenly wet;

[0047] ④The above materials are irradiated under 1KW continuous microwave power until there is liquid reflux, that is, the organic acid solution is vaporized, and the working mode is changed to pulsed microwave power, with a duty cycle of 15 / 5 seconds and a peak power of 5KW. The working pressure of the reaction chamber is 200 mmHg) under reduced pressure distillation, and the organic acid solution is removed until there is no liquid in the microwave chamber, and ...

Embodiment 2

[0063] The difference from Example 1 is:

[0064] 2) Preparation of microwave-softened ganoderma spore powder alcohol extract: take 0.78 kg of the microwave-softened ganoderma spore powder obtained in step 1) and put it into a microwave extraction device, add 6 kg of absolute ethanol, and apply 10 kw of continuous microwave power to reaction chamber When the temperature reaches 60°C, change to pulsed microwave (microwave peak power 10kw, duty cycle: 5 / 5 seconds), turn on the vacuum pump, and keep the liquid temperature at 60°C for 1 hour;

[0065]3) Preparation of microwave-softened ganoderma lucidum spore powder water extract: take all the microwave-softened spore powder residue after step 2) and place it in a microwave extraction device, add 7kg of distilled water, and apply 8kw continuous microwave power until the water temperature reaches 70°C. Then, change to pulsed microwave (microwave peak power 10kw, duty cycle: 5 / 5 seconds), keep it for 50 minutes, and then vacuumize...

Embodiment 3

[0071] The difference from Example 2 is:

[0072] 4) Alcoholic extract of Ganoderma lucidum fruiting body: Weigh 5.5kg of crushed Ganoderma lucidum fruiting body and place it in a microwave extraction device, add 10kg of absolute ethanol, apply 20kw continuous microwave power to the reaction Cavity When the temperature reaches 60°C, change to pulsed microwave (microwave peak power 20kw, duty cycle: 1 / 1 second), turn on the vacuum pump, and keep the liquid temperature at 60°C for 50 minutes;

[0073] 5) Microwave softening treatment of Ganoderma lucidum fruiting bodies: take all the residues of Ganoderma lucidum fruiting bodies after alcohol extraction and carry out microwave softening treatment;

[0074] 6) Preparation of crude polysaccharide extracted from ganoderma lucidum fruiting bodies by microwave softening: Step 5) Place the fruiting bodies softened by microwaves in a microwave extraction device, add 10 kg of distilled water, and irradiate under 20KW continuous microwav...

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Abstract

The invention discloses a glossy ganoderma preparation containing main active substance of glossy ganoderma herb and preparing method, wherein each 100g of the ganoderma spore powder preparation comprises glossy ganoderma polysaccharides 10-50g, triterpene 3-10g, nucleosides 2-6g, amino acid 10-25g, the glossy ganoderma polysaccharide comprises polysaccharide in glossy ganoderma spore powder and polysaccharide in glossy ganoderma fruiting body by the weight ratio of 1 / 9-9 / 1.

Description

technical field [0001] The invention relates to ganoderma deep-processing products, in particular to a ganoderma preparation rich in main active substances of whole ganoderma and a preparation method thereof. Background technique [0002] Ganoderma lucidum is known as "immortal grass" in my country. Ganoderma lucidum has become a drug recorded in the National Pharmacopoeia and a new resource food approved by the state because of its rich natural medicinal ingredients and special pharmacological health effects. It provides abundant natural product resources for promoting the development of the pharmaceutical industry, food industry and light chemical industry. . [0003] In traditional Chinese medicine, Ganoderma lucidum is used to tonify the deficiency of the five viscera, balance yin and yang, and harmonize blood and qi. Ganoderma lucidum is known as the medicine for all diseases". Modern medicine has conducted extensive research on the characteristics, chemical basis, a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61P1/16A61P3/10A61P7/06A61P9/10A61P11/00A61P19/10A61P25/00A61P29/00A61P31/12A61P35/00A61P37/02A61P43/00
Inventor 张劲松李明天
Owner SHENYANG KESI TECH DEV
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